相关论文: Modeling the Heterogeneity in COVID-19's Reproduct…

In this paper we analyze the effects of commuting and social inequalities for the epidemic development of the novel coronavirus (COVID-19). With this aim we consider a SEIRD (susceptible, exposed, infected, recovered and dead by disease)…

We propose a general Bayesian approach to modeling epidemics such as COVID-19. The approach grew out of specific analyses conducted during the pandemic, in particular an analysis concerning the effects of non-pharmaceutical interventions…

The reproductive number R_0 (and its value after initial disease emergence R) has long been used to predict the likelihood of pathogen invasion, to gauge the potential severity of an epidemic, and to set policy around interventions.…

Coronavirus COVID-19 spreads through the population mostly based on social contact. To gauge the potential for widespread contagion, to cope with associated uncertainty and to inform its mitigation, more accurate and robust modelling is…

The role of epidemiological models is crucial for informing public health officials during a public health emergency, such as the COVID-19 pandemic. However, traditional epidemiological models fail to capture the time-varying effects of…

In this article, we consider a dynamic epidemiology model for the spread of the COVID-19 infection. Starting from the classical SEIR model, the model is modified so as to better describe characteristic features of the underlying pathogen…

A major difficulty to estimate $R$ (the effective reproducing number) of COVID-19 is that most cases of COVID-19 infection are mild or asymptomatic, therefore true number of infection is difficult to determine. This paper estimates the…

OBJECTIVES: Estimates of the basic reproduction number (R0) of COVID-19 vary across countries. This paper aims to characterise the spatial variability in R0 across the first six months of the global COVID-19 outbreak, and to explore social…

The expected number of secondary infections arising from each index case, referred to as the reproduction or $R$ number, is a vital summary statistic for understanding and managing epidemic diseases. There are many methods for estimating…

The basic reproductive number -- $R_0$ -- is one of the most common and most commonly misapplied numbers in public health. Although often used to compare outbreaks and forecast pandemic risk, this single number belies the complexity that…

The ongoing Coronavirus disease 2019 (COVID-19) is a major crisis that has significantly affected the healthcare sector and global economies, which made it the main subject of various fields in scientific and technical research. To properly…

The spread of COVID-19 has been greatly impacted by regulatory policies and behavior patterns that vary across counties, states, and countries. Population-level dynamics of COVID-19 can generally be described using a set of ordinary…

A primary quantity of interest in the study of infectious diseases is the average number of new infections that an infected person produces. This so-called reproduction number has significant implications for the disease progression. There…

Comparing how different populations have suffered under COVID-19 is a core part of ongoing investigations into how public policy and social inequalities influence the number of and severity of COVID-19 cases. But COVID-19 incidence can vary…

A well-known characteristic of pandemics such as COVID-19 is the high level of transmission heterogeneity in the infection spread: not all infected individuals spread the disease at the same rate and some individuals (superspreaders) are…

This paper deals with the problem of estimating variables in nonlinear models for the spread of disease and its application to the COVID-19 epidemic. First unconstrained methods are revisited and they are shown to correspond to the…

Standard epidemiological models for COVID-19 employ variants of compartment (SIR) models at local scales, implicitly assuming spatially uniform local mixing. Here, we examine the effect of employing more geographically detailed diffusion…

We investigate the problem of estimating the distribution of the individual reproduction number governing the COVID-19 pandemic. Under the assumption that this random variable follows a Negative Binomial distribution, we focus on…

Modeling the spread of COVID-19 is crucial for informing public health policy. All models for COVID-19 epidemiology rely on parameters describing the dynamics of the infection process. The meanings of epidemiological parameters like R_0,…

Timely prediction of the COVID-19 progression is not possible without a comprehensive understanding of environmental factors that may affect the infection transmissibility. Studies addressing parameters that may influence COVID-19…