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There is large consent that successful training of deep networks requires many thousand annotated training samples. In this paper, we present a network and training strategy that relies on the strong use of data augmentation to use the…

计算机视觉与模式识别 · 计算机科学 2015-05-19 Olaf Ronneberger , Philipp Fischer , Thomas Brox

Segmentation of cell nuclei in microscopy images is a prevalent necessity in cell biology. Especially for three-dimensional datasets, manual segmentation is prohibitively time-consuming, motivating the need for automated methods.…

计算机视觉与模式识别 · 计算机科学 2020-02-10 Peter Hirsch , Dagmar Kainmueller

The automated segmentation and tracking of macrophages during their migration are challenging tasks due to their dynamically changing shapes and motions. This paper proposes a new algorithm to achieve automatic cell tracking in time-lapse…

图像与视频处理 · 电气工程与系统科学 2023-01-03 Seol Ah Park , Tamara Sipka , Zuzana Kriva , George Lutfalla , Mai Nguyen-Chi , Karol Mikula

In this paper we present a methodology that uses convolutional neural networks (CNNs) for segmentation by iteratively growing predicted mask regions in each coordinate direction. The CNN is used to predict class probability scores in a…

图像与视频处理 · 电气工程与系统科学 2020-09-25 John Lagergren , Erica Rutter , Kevin Flores

Tracking living cells in video sequence is difficult, because of cell morphology and high similarities between cells. Tracking-by-detection methods are widely used in multi-cell tracking. We perform multi-cell tracking based on the cell…

计算机视觉与模式识别 · 计算机科学 2019-06-27 Zibin Zhou , Fei Wang , Wenjuan Xi , Huaying Chen , Peng Gao , Chengkang He

This paper presents a method for time-lapse 3D cell analysis. Specifically, we consider the problem of accurately localizing and quantitatively analyzing sub-cellular features, and for tracking individual cells from time-lapse 3D confocal…

计算机视觉与模式识别 · 计算机科学 2022-08-18 Jiaxiang Jiang , Amil Khan , S. Shailja , Samuel A. Belteton , Michael Goebel , Daniel B. Szymanski , B. S. Manjunath

With the advent of convolutional neural networks~(CNN), supervised learning methods are increasingly being used for whole brain segmentation. However, a large, manually annotated training dataset of labeled brain images required to train…

计算机视觉与模式识别 · 计算机科学 2019-03-05 Amod Jog , Andrew Hoopes , Douglas N. Greve , Koen Van Leemput , Bruce Fischl

We present a novel method for cell segmentation in microscopy images which is inspired by the Generative Adversarial Neural Network (GAN) approach. Our framework is built on a pair of two competitive artificial neural networks, with a…

计算机视觉与模式识别 · 计算机科学 2018-09-14 Assaf Arbelle , Tammy Riklin Raviv

Accurate automatic segmentation of brain anatomy from $T_1$-weighted~($T_1$-w) magnetic resonance images~(MRI) has been a computationally intensive bottleneck in neuroimaging pipelines, with state-of-the-art results obtained by unsupervised…

计算机视觉与模式识别 · 计算机科学 2018-08-01 Amod Jog , Bruce Fischl

Analyzing the dynamic changes of cellular morphology is important for understanding the various functions and characteristics of live cells, including stem cells and metastatic cancer cells. To this end, we need to track all points on the…

计算机视觉与模式识别 · 计算机科学 2023-03-16 Junbong Jang , Kwonmoo Lee , Tae-Kyun Kim

Cell segmentation is essential in biomedical research for analyzing cellular morphology and behavior. Deep learning methods, particularly convolutional neural networks (CNNs), have revolutionized cell segmentation by extracting intricate…

图像与视频处理 · 电气工程与系统科学 2024-08-27 Boyuan Peng , Jiaju Chen , P. Bilha Githinji , Ijaz Gul , Qihui Ye , Minjiang Chen , Peiwu Qin , Xingru Huang , Chenggang Yan , Dongmei Yu , Jiansong Ji , Zhenglin Chen

Semantic segmentation of microscopic cell images using deep learning is an important technique, however, it requires a large number of images and ground truth labels for training. To address the above problem, we consider an efficient…

计算机视觉与模式识别 · 计算机科学 2023-04-18 Sota Kato , Kazuhiro Hotta

Automatic cell segmentation in microscopy images works well with the support of deep neural networks trained with full supervision. Collecting and annotating images, though, is not a sustainable solution for every new microscopy database…

计算机视觉与模式识别 · 计算机科学 2020-07-06 Youssef Dawoud , Julia Hornauer , Gustavo Carneiro , Vasileios Belagiannis

Object segmentation and structure localization are important steps in automated image analysis pipelines for microscopy images. We present a convolution neural network (CNN) based deep learning architecture for segmentation of objects in…

计算机视觉与模式识别 · 计算机科学 2019-01-24 Shan E Ahmed Raza , Linda Cheung , Muhammad Shaban , Simon Graham , David Epstein , Stella Pelengaris , Michael Khan , Nasir M. Rajpoot

Convolutional neural networks (CNNs) have achieved state-of-the-art performance for automatic medical image segmentation. However, they have not demonstrated sufficiently accurate and robust results for clinical use. In addition, they are…

Efficient organ segmentation is the precondition of various quantitative analysis. Segmenting the pancreas from abdominal CT images is a challenging task because of its high anatomical variability in shape, size and location. What's more,…

计算机视觉与模式识别 · 计算机科学 2020-03-10 Jinchan He , Xiaxia Yu , Chudong Cai , Yi Gao

Cell tracking is a key computational task in live-cell microscopy, but fully automated analysis of high-throughput imaging requires reliable and, thus, uncertainty-aware data analysis tools, as the amount of data recorded within a single…

计算机视觉与模式识别 · 计算机科学 2025-03-13 Richard D. Paul , Johannes Seiffarth , David Rügamer , Hanno Scharr , Katharina Nöh

Melanoma is a life-threatening form of skin cancer when left undiagnosed at the early stages. Although there are more cases of non-melanoma cancer than melanoma cancer, melanoma cancer is more deadly. Early detection of melanoma is crucial…

图像与视频处理 · 电气工程与系统科学 2020-05-15 Shreshth Saini , Divij Gupta , Anil Kumar Tiwari

Cell tracking and segmentation assist biologists in extracting insights from large-scale microscopy time-lapse data. Driven by local accuracy metrics, current tracking approaches often suffer from a lack of long-term consistency and the…

计算机视觉与模式识别 · 计算机科学 2025-06-30 Timo Kaiser , Maximilian Schier , Bodo Rosenhahn

The throughput of electron microscopes has increased significantly in recent years, enabling detailed analysis of cell morphology and ultrastructure. Analysis of neural circuits at single-synapse resolution remains the flagship target of…

计算机视觉与模式识别 · 计算机科学 2019-08-07 Constantin Pape , Alex Matskevych , Adrian Wolny , Julian Hennies , Giula Mizzon , Marion Louveaux , Jacob Musser , Alexis Maizel , Detlev Arendt , Anna Kreshuk