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Component network meta-analysis (CNMA) models are an extension of standard network meta-analysis (NMA) models which account for the use of multicomponent treatments in the network. This article contributes innovatively to several…

统计方法学 · 统计学 2025-07-23 Augustine Wigle , Audrey Béliveau

Background: Comparative effectiveness research using network meta-analysis can present a hierarchy of competing treatments, from the least to most preferable option. However, the research question associated with the hierarchy of multiple…

Network meta-analysis (NMA) of rare events has attracted little attention in the literature. Until recently, networks of interventions with rare events were analyzed using the inverse-variance NMA approach. However, when events are rare the…

统计方法学 · 统计学 2021-09-22 Theodoros Evrenoglou , Ian White , Sivem Afach , Dimitris Mavridis , Anna Chaimani

Neural network models have become the leading solution for a large variety of tasks, such as classification, language processing, protein folding, and others. However, their reliability is heavily plagued by adversarial inputs: small input…

机器学习 · 计算机科学 2022-10-04 Natan Levy , Guy Katz

Network meta-analysis (NMA) combines direct and indirect comparisons across a connected treatment network to estimate relative treatment effects. However, there is a lack of exact contribution decompositions that reproduce NMA estimates,…

统计方法学 · 统计学 2026-04-27 Chong Wang , Yanqi Zhang , Zhezhen Jin , Annette O'Connor

Asymmetry of in/out-degree distribution is a widespread phenomenon in real-world complex networks. This paper put forward the concept of Edge Asymmetry(EA) to quantify this feature. We designed an EA-based strategy to attack six kinds of…

物理与社会 · 物理学 2018-02-06 Lei Wang , Xincheng Wang

Network meta-analysis (NMA) has been used to answer a range of clinical questions about the preferable intervention for a given condition. Although the effectiveness and safety of pharmacological agents depend on the dose administered, NMA…

Random-effects meta-analyses are very commonly used in medical statistics. Recent methodological developments include multivariate (multiple outcomes) and network (multiple treatments) meta-analysis. Here we provide a new model and…

统计方法学 · 统计学 2017-08-16 Dan Jackson , Sylwia Bujkiewicz , Martin Law , Richard D Riley , Ian White

Network alignment is a problem of finding the node mapping between similar networks. It links the data from separate sources and is widely studied in bioinformation and social network fields. The critical difference between network…

社会与信息网络 · 计算机科学 2021-07-26 Hailong Li , Naiyue Chen

The reliability of the results of network meta-analysis (NMA) lies in the plausibility of key assumption of transitivity. This assumption implies that the effect modifiers' distribution is similar across treatment comparisons. Transitivity…

统计方法学 · 统计学 2023-10-06 Georgios Seitidis , Stavros Nikolakopoulos , Ioannis Ntzoufras , Dimitris Mavridis

Network analysis provides powerful tools to learn about a variety of social systems. However, most analyses implicitly assume that the considered relational data is error-free, reliable and accurately reflects the system to be analysed.…

社会与信息网络 · 计算机科学 2022-01-12 Felix I. Stamm , Leonie Neuhäuser , Florian Lemmerich , Michael T. Schaub , Markus Strohmaier

Real networks often have severe degree heterogeneity, with the maximum, average, and minimum node degrees differing significantly. This paper examines the impact of degree heterogeneity on statistical limits of network data analysis.…

统计理论 · 数学 2024-07-24 Zheng Tracy Ke , Jingming Wang

While standard meta-analysis pools the results from randomized trials that compare two treatments, network meta-analysis aggregates the results of randomized trials comparing a wider variety of treatment options. However, it is unclear…

统计方法学 · 统计学 2016-08-15 Mireille E. Schnitzer , Russell J. Steele , Michèle Bally , Ian Shrier

The surrounding of a vertex in a network can be more or less symmetric. We derive measures of a specific kind of symmetry of a vertex which we call degree symmetry -- the property that many paths going out from a vertex have overlapping…

数据分析、统计与概率 · 物理学 2007-05-23 Petter Holme

Decisions based upon pairwise comparisons of multiple treatments are naturally performed in terms of the mean survival of the selected study arms or functions thereof. However, synthesis of treatment comparisons is usually performed on…

应用统计 · 统计学 2025-12-11 Anastasios Apsemidis , Dimitris Mavridis , Nikolaos Demiris

There has been a transition from broad to more specific research questions in the practice of network meta-analysis (NMA). Such convergence is also taking place in the context of individual registrational trials, following the recent…

应用统计 · 统计学 2026-05-07 Antonio Remiro-Azócar , Anders Gorst-Rasmussen

Explicit modelling of between-study heterogeneity is essential in network meta-analysis (NMA) to ensure valid inference and avoid overstating precision. While the additive random-effects (RE) model is the conventional approach, the…

统计方法学 · 统计学 2026-01-21 Xinlei Xu , Caitlin H Daly , Audrey Béliveau

The stability of networks is greatly influenced by their degree distributions and in particular by their broadness. Networks with broader degree distributions are usually more robust to random failures but less robust to localized attacks.…

物理与社会 · 物理学 2015-09-23 Xin Yuan , Shuai Shao , H. Eugene Stanley , Shlomo Havlin

Dropout Regularization, serving to reduce variance, is nearly ubiquitous in Deep Learning models. We explore the relationship between the dropout rate and model complexity by training 2,000 neural networks configured with random…

机器学习 · 计算机科学 2021-08-30 Christopher Sun , Jai Sharma , Milind Maiti

This article discusses the properties of extremes of degree sequences calculated from network data. We introduce the notion of a normalized degree, in order to permit a comparison of degree sequences between networks with differing numbers…

统计方法学 · 统计学 2012-10-17 Sofia C. Olhede , Patrick J. Wolfe