相关论文: Bistability and oscillations in cooperative microt…
The microtubule cytoskeleton is comprised of dynamic, polarized filaments that facilitate transport within the cell. Polarized microtubule arrays are key to facilitating cargo transport in long cells such as neurons. Microtubules also…
Multistability is an inseparable feature of many physical, chemical and biological systems which are driven far from equilibrium. In these nonequilibrium systems, stochastic dynamics often induces switching between distinct states on…
Protoplanetary discs may become dynamically unstable due to structure induced by an embedded giant planet. In this thesis, I discuss the stability of such systems and explore the consequence of instability on planetary migration. I begin…
In this work, we experimentally investigate the dynamics of pairs of opto-thermally driven, mechanically coupled, doubly clamped, silicon micromechanical oscillators, and numerically investigate the dynamics of the corresponding…
We examine the dynamics of resonance locking in detached, tidally interacting binary systems. In a resonance lock, a given stellar or planetary mode is trapped in a highly resonant state for an extended period of time, during which the spin…
We investigate the dynamics of an active gel of bundled microtubules that is driven by clusters of kinesin molecular motors. Upon the addition of ATP, the coordinated action of thousands of molecular motors drives the gel to a highly…
The behaviour of semi-dilute wormlike micelle solutions under vertical vibrations is investigated using classical measurements of the Faraday instability threshold along with two new experiments based on particle imaging velocimetry and…
In this paper we study noise-induced bistability in a specific circuit with many biological implications, namely a single-step enzymatic cycle described by Michaelis Menten equations with quasi-steady state assumption. We study the system…
Context: The Circular Restricted Three-Body Problem provides a fundamental framework for understanding resonant dynamics in binary star systems. Aims: We develop a unified Hamiltonian formulation for mean-motion resonances that encompasses…
We consider the dynamics of a periodic chain of N coupled overdamped particles under the influence of noise. Each particle is subjected to a bistable local potential, to a linear coupling with its nearest neighbours, and to an independent…
Cilia and flagella are highly conserved slender organelles that exhibit a variety of rhythmic beating patterns from non-planar cone-like motions to planar wave-like deformations. Although their internal structure, composed of a…
The dynamics of microcapsules in steady shear flow was studied using a theoretical approach based on three variables: The Taylor deformation parameter $\alpha_{\rm D}$, the inclination angle $\theta$, and the phase angle $\phi$ of the…
We introduce a stochastic lattice gas model including two particle species and two parallel lanes. One lane with exclusion interaction and directed motion and the other lane without exclusion and unbiased diffusion, mimicking a micotubule…
In this study, a two-state mechanochemical model is presented to describe the dynamic instability of microtubules (MTs) in cells. The MTs switches between two states, assembly state and disassembly state. In assembly state, the growth of…
During cell division paired (sister) chromosomes are observed to perform approximate saw-tooth oscillations across the cell mid-plane. Experimental data suggests that these oscillations are regulated through intersister tension. We propose…
Robust oscillations play crucial roles in a wide variety of biological processes and are often generated by deterministic mechanisms. However, stochastic fluctuations often generate complex perturbations of these deterministic oscillations,…
We propose a two-dimensional model for the organization of stabilized microtubules driven by molecular motors in an unconfined geometry. In this model two kinds of dynamics are competing. The first one is purely diffusive, with an…
The apparent stability of population oscillations in ecological systems is a long-standing puzzle. A generic solution for this problem is suggested here. The stabilizing mechanism involves the combined effect of spatial migration,…
Stall cells are spanwise-periodic flow structures that spontaneously form on airfoils operating near stall, fundamentally altering the aerodynamic loading distribution. Despite decades of experimental observations, a complete theoretical…
Microtubules, the primary components of the chromosome segregation machinery, are stabilized by longitudinal and lateral non-covalent bonds between the tubulin subunits. However, the thermodynamics of these bonds and the microtubule…