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The understanding of neural activity patterns is fundamentally linked to an understanding of how the brain's network architecture shapes dynamical processes. Established approaches rely mostly on deviations of a given network from certain…

神经元与认知 · 定量生物学 2014-09-19 Marc-Thorsten Huett , Marcus Kaiser , Claus C. Hilgetag

Networks involved in information processing often have their nodes arranged hierarchically, with the majority of connections occurring in adjacent levels. However, despite being an intuitively appealing concept, the hierarchical…

神经元与认知 · 定量生物学 2024-07-02 Anand Pathak , Shakti N. Menon , Sitabhra Sinha

Connectivity patterns of relevance in neuroscience and systems biology can be encoded in hierarchical modular networks (HMNs). Moreover, recent studies highlight the role of hierarchical modular organization in shaping brain activity…

无序系统与神经网络 · 物理学 2017-11-22 Ali Safari , Paolo Moretti , Miguel A. Muñoz

Complex networks encountered in biology are often characterized by significant structural diversity. Whether it be differences in the three-dimensional structure of allosteric proteins, or the variation among the micro-scale structures of…

物理与社会 · 物理学 2020-08-19 Jason W. Rocks , Andrea J. Liu , Eleni Katifori

The human brain has been studied at multiple scales, from neurons, circuits, areas with well defined anatomical and functional boundaries, to large-scale functional networks which mediate coherent cognition. In a recent work, we addressed…

生物物理 · 物理学 2012-05-17 Lazaros K. Gallos , Mariano Sigman , Hernan A. Makse

Networks have in recent years emerged as an invaluable tool for describing and quantifying complex systems in many branches of science. Recent studies suggest that networks often exhibit hierarchical organization, where vertices divide into…

机器学习 · 统计学 2008-11-05 Aaron Clauset , Cristopher Moore , M. E. J. Newman

The brain can be considered as a system that dynamically optimizes the structure of anatomical connections based on the efficiency requirements of functional connectivity. To illustrate the power of this principle in organizing the…

神经元与认知 · 定量生物学 2024-02-07 Carlos Calvo Tapia , Valeriy A. Makarov Slizneva , Cees van Leeuwen

Real-world networks often benefit from capturing both local and global interactions. Inspired by multi-modal analysis in brain imaging, where structural and functional connectivity offer complementary views of network organization, we…

神经与进化计算 · 计算机科学 2025-08-11 Yang Li , Luopeiwen Yi , Tananun Songdechakraiwut

The brain is a complex organ characterized by heterogeneous patterns of structural connections supporting unparalleled feats of cognition and a wide range of behaviors. New noninvasive imaging techniques now allow these patterns to be…

神经元与认知 · 定量生物学 2020-04-03 Christopher W. Lynn , Danielle S. Bassett

The relationship of network structure and dynamics is one of most extensively investigated problems in the theory of complex systems of the last years. Understanding this relationship is of relevance to a range of disciplines -- from…

Activity in coupled systems is often oscillatory, for example, the firing pattern of neuronal populations. Whereas these oscillations have been studied predominantly in local circuits, here we show how the topology of large-scale networks,…

神经元与认知 · 定量生物学 2014-05-15 Marcus Kaiser

Intrinsic brain activity is characterized by highly structured co-activations between different regions, whose origin is still under debate. In this paper, we address the question whether it is possible to unveil how the underlying…

The organization in brain networks shows highly modular features with weak inter-modular interaction. The topology of the networks involves emergence of modules and sub-modules at different levels of constitution governed by fractal laws.…

Large-scale white matter pathways crisscrossing the cortex create a complex pattern of connectivity that underlies human cognitive function. Generative mechanisms for this architecture have been difficult to identify in part because little…

神经元与认知 · 定量生物学 2015-06-16 Florian Klimm , Danielle S. Bassett , Jean M. Carlson , Peter J. Mucha

Neuronal networks constitute a special class of dynamical systems, as they are formed by individual geometrical components, namely the neurons. In the existing literature, relatively little attention has been given to the influence of…

神经元与认知 · 定量生物学 2015-05-13 Sebastian Ahnert , Luciano da Fontoura Costa

The brain is immensely complex, with diverse components and dynamic interactions building upon one another to orchestrate a wide range of functions and behaviors. Understanding patterns of these complex interactions and how they are…

神经元与认知 · 定量生物学 2024-08-06 Suman Kulkarni , Dani S. Bassett

The relationship between network topology and system dynamics has significant implications for unifying our understanding of the interplay among metabolic, gene-regulatory, and ecosystem network architecures. Here we analyze the stability…

种群与进化 · 定量生物学 2015-06-17 Cameron Smith , Raymond S. Puzio , Aviv Bergman

The human brain is a complex system, and understanding its mechanisms has been a long-standing challenge in neuroscience. The study of the functional connectome, which maps the functional connections between different brain regions, has…

神经与进化计算 · 计算机科学 2025-04-14 Tananun Songdechakraiwut , Yutong Wu

The relation between large-scale brain structure and function is an outstanding open problem in neuroscience. We approach this problem by studying the dynamical regime under which realistic spatio-temporal patterns of brain activity emerge…

神经元与认知 · 定量生物学 2014-05-27 Ariel Haimovici , Enzo Tagliazucchi , Pablo Balenzuela , Dante R. Chialvo

Network control theory has recently emerged as a promising approach for understanding brain function and dynamics. By operationalizing notions of control theory for brain networks, it offers a fundamental explanation for how brain dynamics…

定量方法 · 定量生物学 2020-03-20 Shikuang Deng , Shi Gu
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