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Two non-intrusive uncertainty propagation approaches are proposed for the performance analysis of engineering systems described by expensive-to-evaluate deterministic computer models with parameters defined as interval variables. These…

信号处理 · 电气工程与系统科学 2022-02-15 Alice Cicirello , Filippo Giunta

Missing data is a common problem in medical research, and is commonly addressed using multiple imputation. Although traditional imputation methods allow for valid statistical inference when data are missing at random (MAR), their…

Hierarchical learning models, such as mixture models and Bayesian networks, are widely employed for unsupervised learning tasks, such as clustering analysis. They consist of observable and hidden variables, which represent the given data…

机器学习 · 统计学 2018-01-08 Keisuke Yamazaki

As one of the most commonly seen data challenges, missing data, in particular, multiple, non-monotone missing patterns, complicates estimation and inference due to the fact that missingness mechanisms are often not missing at random, and…

统计方法学 · 统计学 2025-04-21 Jianing Dong , Raymond K. W. Wong , Kwun Chuen Gary Chan

Missing data is a common problem in real-world settings and particularly relevant in healthcare applications where researchers use Electronic Health Records (EHR) and results of observational studies to apply analytics methods. This issue…

机器学习 · 统计学 2018-12-04 Dimitris Bertsimas , Agni Orfanoudaki , Colin Pawlowski

Mental disorders impact the lives of millions of people globally, not only impeding their day-to-day lives but also markedly reducing life expectancy. This paper addresses the persistent challenge of predicting mortality in patients with…

机器学习 · 计算机科学 2023-10-19 Sean Kim , Samuel Kim

Large-scale pretraining has transformed modeling of language and other data types, but its potential remains underexplored in healthcare with structured electronic health records (EHRs). We present a novel generative pretraining strategy…

Assessing the practical identifiability of epidemic models is essential for determining whether parameters can be meaningfully estimated from observed data. Monte Carlo (MC) methods provide an accessible and intuitive framework; however,…

统计方法学 · 统计学 2025-10-01 Chiara Mattamira , Olivia Prosper Feldman

International comparisons of hierarchical time series data sets based on survey data, such as annual country-level estimates of school enrollment rates, can suffer from large amounts of missing data due to differing coverage of surveys…

统计方法学 · 统计学 2025-03-31 Daphne H. Liu , Adrian E. Raftery

Missing values are largely inevitable in gene expression microarray studies. Data sets often have significant omissions due to individuals dropping out of experiments, errors in data collection, image corruptions, and so on. Missing data…

定量方法 · 定量生物学 2018-09-18 Marie Li

Evaluating the clinical similarities between pairwise patients is a fundamental problem in healthcare informatics. A proper patient similarity measure enables various downstream applications, such as cohort study and treatment comparative…

机器学习 · 统计学 2019-02-12 Zihao Zhu , Changchang Yin , Buyue Qian , Yu Cheng , Jishang Wei , Fei Wang

Survival models are used in various fields, such as the development of cancer treatment protocols. Although many statistical and machine learning models have been proposed to achieve accurate survival predictions, little attention has been…

机器学习 · 计算机科学 2020-03-26 Hrushikesh Loya , Pranav Poduval , Deepak Anand , Neeraj Kumar , Amit Sethi

Uncertainty estimation has been widely studied in medical image segmentation as a tool to provide reliability, particularly in deep learning approaches. However, previous methods generally lack effective supervision in uncertainty…

计算机视觉与模式识别 · 计算机科学 2025-10-15 Yuzhu Li , An Sui , Fuping Wu , Xiahai Zhuang

This paper aims to build an estimate of an unknown density of the data with measurement error as a linear combination of functions from a dictionary. Inspired by the penalization approach, we propose the weighted Elastic-net penalized…

统计理论 · 数学 2020-07-07 Xiaowei Yang , Huiming Zhang , Haoyu Wei , Shouzheng Zhang

Missing value imputation is an important practical problem. There is a large body of work on it, but there does not exist any work that formulates the problem in a structured output setting. Also, most applications have constraints on the…

机器学习 · 计算机科学 2013-11-12 Rahul Kidambi , Vinod Nair , Sundararajan Sellamanickam , S. Sathiya Keerthi

Medical multimodal learning faces significant challenges with missing modalities prevalent in clinical practice. Existing approaches assume equal contribution of modality and random missing patterns, neglecting inherent uncertainty in…

机器学习 · 计算机科学 2026-01-30 Linxiao Gong , Yang Liu , Lianlong Sun , Yulai Bi , Jing Liu , Xiaoguang Zhu

Electronic medical records (EMR) contain longitudinal information about patients that can be used to analyze outcomes. Typically, studies on EMR data have worked with established variables that have already been acknowledged to be…

机器学习 · 计算机科学 2017-11-30 Prithwish Chakraborty , Vishrawas Gopalakrishnan , Sharon M. H. Alford , Faisal Farooq

A major challenge in embedding or visualizing clinical patient data is the heterogeneity of variable types including continuous lab values, categorical diagnostic codes, as well as missing or incomplete data. In particular, in EHR data,…

Electronic healthcare records (EHR) contain a huge wealth of data that can support the prediction of clinical outcomes. EHR data is often stored and analysed using clinical codes (ICD10, SNOMED), however these can differ across registries…

机器学习 · 计算机科学 2024-12-03 Elizabeth Remfry , Rafael Henkin , Michael R Barnes , Aakanksha Naik

Electronic health records (EHRs) offer great promises for advancing precision medicine and, at the same time, present significant analytical challenges. Particularly, it is often the case that patient-level data in EHRs cannot be shared…

统计方法学 · 统计学 2022-07-04 Changgee Chang , Zhiqi Bu , Qi Long