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In a mathematical model of interacting biological organisms, where external interventions may alter behavior over time, traditional models that assume fixed parameters usually do not capture the evolving dynamics. In oncology, this is…

机器学习 · 计算机科学 2025-12-18 Kayode Olumoyin , Lamees El Naqa , Katarzyna Rejniak

Open-domain dialogue generation suffers from the data insufficiency problem due to the vast size of potential responses. In this paper, we propose to explore potential responses by counterfactual reasoning. Given an observed response, the…

机器学习 · 计算机科学 2020-10-12 Qingfu Zhu , Weinan Zhang , Ting Liu , William Yang Wang

Time series models with recurrent neural networks (RNNs) can have high accuracy but are unfortunately difficult to interpret as a result of feature-interactions, temporal-interactions, and non-linear transformations. Interpretability is…

机器学习 · 计算机科学 2021-09-17 Asif Rahman , Yale Chang , Jonathan Rubin

Since sequential information plays an important role in modeling user behaviors, various sequential recommendation methods have been proposed. Methods based on Markov assumption are widely-used, but independently combine several most recent…

信息检索 · 计算机科学 2016-09-20 Qiang Liu , Shu Wu , Diyi Wang , Zhaokang Li , Liang Wang

The widespread availability of electronic health records (EHRs) promises to usher in the era of personalized medicine. However, the problem of extracting useful clinical representations from longitudinal EHR data remains challenging. In…

机器学习 · 计算机科学 2017-01-27 Zhengping Che , Yu Cheng , Zhaonan Sun , Yan Liu

Although numerous complex algorithms for treatment effect estimation have been developed in recent years, their effectiveness remains limited when handling insufficiently labeled training sets due to the high cost of labeling the effect…

机器学习 · 计算机科学 2025-05-09 Hechuan Wen , Tong Chen , Mingming Gong , Li Kheng Chai , Shazia Sadiq , Hongzhi Yin

This work presents CounterNet, a novel end-to-end learning framework which integrates Machine Learning (ML) model training and the generation of corresponding counterfactual (CF) explanations into a single end-to-end pipeline.…

机器学习 · 计算机科学 2023-06-23 Hangzhi Guo , Thanh Hong Nguyen , Amulya Yadav

Designed as extremely deep architectures, deep residual networks which provide a rich visual representation and offer robust convergence behaviors have recently achieved exceptional performance in numerous computer vision problems. Being…

计算机视觉与模式识别 · 计算机科学 2017-04-13 T. Hoang Ngan Le , Chi Nhan Duong , Ligong Han , Khoa Luu , Marios Savvides , Dipan Pal

Recurrent events, characterized by the repeated occurrence of the same event in an individual, are a common type of data in medical research. Motivated by cancer recurrences, we aim to estimate the optimal individualized treatment regime…

统计方法学 · 统计学 2025-02-18 Zi-Shu Zhan , Jin-Lun Zhang , Chen Shi , Xiao-Han Xu , Chun-Quan Ou

Over the long history of machine learning, which dates back several decades, recurrent neural networks (RNNs) have been used mainly for sequential data and time series and generally with 1D information. Even in some rare studies on 2D…

计算机视觉与模式识别 · 计算机科学 2021-03-05 Nguyen Huu Phong , Bernardete Ribeiro

Identifying topics of discussions in online health communities (OHC) is critical to various applications, but can be difficult because topics of OHC content are usually heterogeneous and domain-dependent. In this paper, we provide a…

计算与语言 · 计算机科学 2016-04-08 Shaodian Zhang , Edouard Grave , Elizabeth Sklar , Noemie Elhadad

Despite significant medical advancements, cancer remains the second leading cause of death, with over 600,000 deaths per year in the US. One emerging field, pathway analysis, is promising but still relies on manually derived wet lab data,…

机器学习 · 计算机科学 2025-09-17 Rishab Parthasarathy , Achintya Bhowmik

With the ongoing rise of machine learning, the need for methods for explaining decisions made by artificial intelligence systems is becoming a more and more important topic. Especially for image classification tasks, many state-of-the-art…

机器学习 · 计算机科学 2022-05-10 Silvan Mertes , Tobias Huber , Katharina Weitz , Alexander Heimerl , Elisabeth André

Stress testing poses a causal question: how would portfolio credit losses change if the macroeconomy followed an adverse counterfactual path? Yet standard practice remains predictive and might be therefore vulnerable to omitted-variable…

人工智能 · 计算机科学 2026-05-19 Yu Wang , Xiangchen Liu , Siguang Li

Speech enhancement has benefited from the success of deep learning in terms of intelligibility and perceptual quality. Conventional time-frequency (TF) domain methods focus on predicting TF-masks or speech spectrum,via a naive convolution…

音频与语音处理 · 电气工程与系统科学 2021-04-16 Liming Zhou , Yongyu Gao , Ziluo Wang , Jiwei Li , Wenbin Zhang

Quantifying uncertainty in predictions or, more generally, estimating the posterior conditional distribution, is a core challenge in machine learning and statistics. We introduce Convex Nonparanormal Regression (CNR), a conditional…

机器学习 · 统计学 2021-09-15 Yonatan Woodbridge , Gal Elidan , Ami Wiesel

Computed tomography (CT) is critical for various clinical applications, e.g., radiotherapy treatment planning and also PET attenuation correction. However, CT exposes radiation during acquisition, which may cause side effects to patients.…

计算机视觉与模式识别 · 计算机科学 2016-12-19 Dong Nie , Roger Trullo , Caroline Petitjean , Su Ruan , Dinggang Shen

Clinical risk prediction is a valuable tool for guiding healthcare interventions toward those most likely to benefit. Yet, evaluating the pairing of a risk prediction model with an intervention using randomized controlled trials presents…

统计方法学 · 统计学 2025-10-31 Valerie Odeh-Couvertier , Gabriel Zayas-Caban , Brian Patterson , Amy Cochran

In this paper, we address the challenge of performing counterfactual inference with observational data via Bayesian nonparametric regression adjustment, with a focus on high-dimensional settings featuring multiple actions and multiple…

机器学习 · 计算机科学 2022-11-22 Alberto Caron , Gianluca Baio , Ioanna Manolopoulou

Dynamic treatment recommendation systems based on large-scale electronic health records (EHRs) become a key to successfully improve practical clinical outcomes. Prior relevant studies recommend treatments either use supervised learning…

机器学习 · 计算机科学 2018-09-18 Lu Wang , Wei Zhang , Xiaofeng He , Hongyuan Zha
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