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相关论文: Beyond $R_0$: Heterogeneity in secondary infection…

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When controlling an emerging outbreak of an infectious disease it is essential to know the key epidemiological parameters, such as the basic reproduction number $R_0$ and the control effort required to prevent a large outbreak. These…

种群与进化 · 定量生物学 2016-04-18 Pieter Trapman , Frank Ball , Jean-Stéphane Dhersin , Viet Chi Tran , Jacco Wallinga , Tom Britton

The basic reproduction number R0 -- the number of individuals directly infected by an infectious person in an otherwise susceptible population -- is arguably the most widely used estimator of how severe an epidemic outbreak can be. This…

种群与进化 · 定量生物学 2016-03-18 Petter Holme , Naoki Masuda

A social (sexual) network is modeled by an extension of the configuration model to the situation where edges have weights, e.g. reflecting the number of sex-contacts between the individuals. An epidemic model is defined on the network such…

概率论 · 数学 2011-12-21 Tom Britton , David Lindenstrand

In the face of an infectious disease, a key epidemiological measure is the basic reproduction number, which quantifies the average secondary infections caused by a single case in a susceptible population. In practice, the effective…

物理与社会 · 物理学 2025-03-11 Xin-Jian Xu , Song-Jie He , Li-Jie Zhang

When an infectious disease strikes a population, the number of newly reported cases is often the only available information that one can obtain during early stages of the outbreak. An important goal of early outbreak analysis is to obtain a…

定量方法 · 定量生物学 2013-05-30 Bahman Davoudi , Babak Pourbohloul , Joel Miller , Rafael Meza , Lauren Ancel Meyers , David J. D. Earn

The basic reproduction number, $R_0$ is an important and widely used concept in the study of infectious diseases. We briefly review the recent trend of calculating the average of various $R_0$ estimates in systematic reviews aimed at…

种群与进化 · 定量生物学 2021-12-13 Pratyush K. Kollepara , Joel C. Miller

Accurate epidemic forecasting requires models that account for the layered and heterogeneous nature of real social interactions. The basic reproduction number $\mathcal R_0$ calculated from models that assume homogeneous mixing or…

We study the SIR model of epidemics on positively correlated heterogeneous networks with population variability, and explore the dependence of the final outbreak size on the network heterogeneity strength and basic reproduction number $R_0$…

统计力学 · 物理学 2023-06-16 Alexander Leibenzon , Michael Assaf

The basic reproduction number of a networked epidemic model, denoted $R_0$, can be computed from a network's topology to quantify epidemic spread. However, disclosure of $R_0$ risks revealing sensitive information about the underlying…

社会与信息网络 · 计算机科学 2025-06-23 Bo Chen , Baike She , Calvin Hawkins , Alex Benvenuti , Brandon Fallin , Philip E. Paré , Matthew Hale

The basic reproduction number ($R_0$) is an epidemiological metric that represents the average number of new infections caused by a single infectious individual in a completely susceptible population. The methodology for calculating this…

代数拓扑 · 数学 2025-12-05 Trevor Reckell , Beckett Sterner , Petar Jevtić

The basic reproduction number $R_0$ is a fundamental quantity in epidemiological modeling, reflecting the typical number of secondary infections that arise from a single infected individual. While $R_0$ is widely known to scientists,…

最优化与控制 · 数学 2022-09-05 Kevin D. Smith , Francesco Bullo

A key parameter in models for the spread of infectious diseases is the basic reproduction number $R_0$, which is the expected number of secondary cases a typical infected primary case infects during its infectious period in a large mostly…

种群与进化 · 定量生物学 2017-09-05 Kristoffer Spricer , Pieter Trapman

Many infectious diseases can lead to re-infection. We examined the relationship between the prevalence of repeat infection and the basic reproductive number (R0). First we solved a generic, deterministic compartmental model of re-infection…

种群与进化 · 定量生物学 2019-03-15 Joshua Feldman , Sharmistha Mishra

The basic and effective reproduction numbers are widely used metrics for characterizing the dynamics of infectious disease epidemics. However, the interpretation of these numbers is based on the assumption of homogeneous mixing and may not…

种群与进化 · 定量生物学 2026-03-24 Zahra Ghadiri , Jari Saramäki , Takayuki Hiraoka

The basic reproduction number, $R_0$, is a well-known quantifier of epidemic spread. However, a class of existing methods for estimating $R_0$ from incidence data early in the epidemic can lead to an over-estimation of this quantity. In…

种群与进化 · 定量生物学 2024-03-27 Wajid Ali , Christopher E. Overton , Robert R. Wilkinson , Kieran J. Sharkey

For a heterogeneous host population, the basic reproduction number of an infectious disease, $\cR_0$, is defined as the spectral radius of the next generation operator (NGO). The threshold properties of the basic reproduction number are…

种群与进化 · 定量生物学 2025-04-29 Horst R Thieme

In this paper we first introduce the general stochastic epidemic model for the spread of infectious diseases. Then we give methods for inferring model parameters such as the basic reproduction number $R_0$ and vaccination coverage $v_c$…

统计方法学 · 统计学 2014-11-14 Tom Britton , Federica Giardina

Branching processes are widely used to model evolutionary and population dynamics as well as the spread of infectious diseases. To characterize the dynamics of their growth or spread, the basic reproduction number $R_0$ has received…

种群与进化 · 定量生物学 2021-09-02 Johannes Pausch , Rosalba Garcia-Millan , Gunnar Pruessner

The correct evaluation of the reproductive number $R$ for COVID-19 -- which characterizes the average number of secondary cases generated by each typical primary case -- is central in the quantification of the potential scope of the…

应用统计 · 统计学 2021-04-15 Claire Donnat , Susan Holmes

A general stochastic model for susceptible -> infective -> recovered (SIR) epidemics in non homogeneous populations is considered. The heterogeneity is a very important aspect here since it allows more realistic but also more complex…

种群与进化 · 定量生物学 2020-08-13 Zeynep Gökçe İşlier , Wolfgang Hörmann , Refik Güllü
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