中文
相关论文

相关论文: The weakest link bridging germinal center B cells …

200 篇论文

The immune system normally protects the human host against death by infection. However, when an immune response is mistakenly directed at self antigens, autoimmune disease can occur. We describe a model of protein evolution to simulate the…

种群与进化 · 定量生物学 2009-11-11 Jun Sun , David J. Earl , Michael W. Deem

The eukaryotic cell membrane is connected to a dense actin rich cortex. We present FCS and STED experiments showing that dense membrane bound actin networks have severe influence on lipid phase separation. A minimal actin cortex was bound…

软凝聚态物质 · 物理学 2018-10-17 Alf Honigmann , Sina Sadeghi , Jan Keller , Stefan W. Hell , Christian Eggeling , Richard Vink

Cell adhesion, a fundamental process of cell biology is involved in the embryo development and in numerous pathologies especially those related to cancers. We constrained cells to adhere on extracellular matrix proteins patterned in a micro…

生物物理 · 物理学 2009-08-25 Herve Guillou , Benoit Vianay , Jacques Chaussy , Marc R. Block

We propose a novel mechanism of cell motility, which relies on the coupling of actin polymerization at the cell membrane to geometric confinement. We consider a polymerizing viscoelastic cytoskeletal gel confined in a narrow channel, and…

软凝聚态物质 · 物理学 2009-02-13 R. J. Hawkins , M. Piel , G. Faure-Andre , A. M. Lennon-Dumenil , J. F. Joanny , J. Prost , R. Voituriez

A well-known lower bound widely used in the massive MIMO literature hinges on channel hardening, i.e., the phenomenon for which, thanks to the large number of antennas, the effective channel coefficients resulting from beamforming tend to…

信息论 · 计算机科学 2017-10-27 Giuseppe Caire

We establish a relationship between decay centrality and two widely used and computationally cheaper measures of centrality, namely degree and closeness. We show that for low values of the decay parameter the nodes with maximum decay…

社会与信息网络 · 计算机科学 2017-01-05 Nikolas Tsakas

Two mobile users communicate with a central decoder via two base stations. Communication between the mobile users and the base stations takes place over a Gaussian interference channel with constant channel gains or quasi-static fading.…

信息论 · 计算机科学 2013-01-30 Roy Karasik , Osvaldo Simeone , Shlomo Shamai

The binding affinity between the T-cell receptors (TCRs) and antigenic peptides mainly determines immunological recognition. It is not a trivial task that T cells identify the digital sequences of peptide amino acids by simply relying on…

细胞行为 · 定量生物学 2024-02-14 Jin Xu , Junghyo Jo

The rigidity of elastic networks depends sensitively on their internal connectivity and the nature of the interactions between constituents. Particles interacting via central forces undergo a zero-temperature rigidity-percolation transition…

软凝聚态物质 · 物理学 2011-12-08 Chase P. Broedersz , Xiaoming Mao , T. C. Lubensky , F. C. MacKintosh

F-ABC is introduced, using universal sufficient statistics, unlike previous ABC papers, e.g. Bernton et al. (2019), and avoiding in the approximate posterior artifacts due to a Kernel. The nature of matching tolerance is examined and…

统计方法学 · 统计学 2020-07-14 Yannis G. Yatracos

We study "buried" active galactic nuclei (AGNs) almost fully covered by circumnuclear material in ultra-/luminous infrared galaxies (U/LIRGs), which show weak ionized lines from narrow line regions. Employing an indicator of [O IV] 25.89-um…

Mechanical coupling between a cell and substrate relies on focal adhesions, clusters of adhesion proteins linking stress fibers (bundles of actin proteins) inside the cell with surrounding tissue. Focal adhesions have been demonstrated to…

软凝聚态物质 · 物理学 2007-05-23 Thomas Bickel , Robijn Bruinsma

We present an exhaustive study of Andreev crystals (ACs) -- quasi-one-dimensional superconducting wires with a periodic distribution of magnetic regions. The exchange field in these regions is assumed to be much smaller than the Fermi…

超导电性 · 物理学 2021-08-18 Mikel Rouco , F Sebastian Bergeret , Ilya V Tokatly

Coordinated multipoint (CoMP) communications are considered for the fifth-generation (5G) small-cell networks as a tool to improve the high data rates and the cell-edge throughput. The average achievable rates of the small-cell base…

网络与互联网体系结构 · 计算机科学 2017-08-25 Fen Bin , Jiaqi Chen , Xiaohu Ge , Wei Xiang

Cell adhesion proteins are transmembrane proteins that bind cells to their environment. These proteins typically cluster into disk-shaped or linear structures. Here we show that such clustering patterns spontaneously emerge when the protein…

软凝聚态物质 · 物理学 2023-07-10 Shao-Zhen Lin , Rishita Changede , Michael P. Sheetz , Jacques Prost , Jean-Francois Rupprecht

Negative compressibility generated by many-body effects in 2D electronic systems can enhance gate capacitance. We observe capacitance enhancement in a newly emerged 2D layered material, atomically thin black phosphorus (BP). The…

介观与纳米尺度物理 · 物理学 2016-04-05 Yingying Wu , Xiaolong Chen , Zefei Wu , Shuigang Xu , Tianyi Han , Jiangxiazi Lin , Yuan Cai , Yuheng He , Chun Cheng , Ning Wang

In many social complex systems, in which agents are linked by non-linear interactions, the history of events strongly influences the whole network dynamics. However, a class of "commonly accepted beliefs" seems rarely studied. In this…

Our traditional notion of a cell is changing dramatically given the increasing degree of heterogeneity in 4G and emerging 5G systems. Rather than belonging to a specific cell, a device would choose the most suitable connection from the…

网络与互联网体系结构 · 计算机科学 2014-10-28 Katerina Smiljkovikj , Hisham Elshaer , Petar Popovski , Federico Boccardi , Mischa Dohler , Liljana Gavrilovska , Ralf Irmer

Simple growth mechanisms have been proposed to explain the emergence of seemingly universal network structures. The widely-studied model of preferential attachment assumes that new nodes are more likely to connect to highly connected nodes.…

物理与社会 · 物理学 2016-03-09 Chung Yin Leung , Joshua S. Weitz

Alzheimer's disease is the most common neurodegenerative disease. The aim of this study is to infer structural changes in brain connectivity resulting from disease progression using cortical thickness measurements from a cohort of…