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In recent years, volumetric modulated arc therapy (VMAT) has been becoming a more and more important radiation technique widely used in clinical application for cancer treatment. One of the key problems in VMAT is treatment plan…

医学物理 · 物理学 2016-01-06 Yu Yang , Bin Dong , Zaiwen Wen

This paper deals with operational models for integrated shift and task scheduling problem. Staff scheduling problem is a special case of this with staff requirements as given input to the problem. Both problems become hard to solve when the…

最优化与控制 · 数学 2022-08-17 G S R Murthy , T R Lalita

Stochastic resetting, the procedure of stopping and re-initializing random processes, has recently emerged as a powerful tool for accelerating processes ranging from queuing systems to molecular simulations. However, its usefulness is…

统计力学 · 物理学 2025-03-18 Tommer D. Keidar , Ofir Blumer , Barak Hirshberg , Shlomi Reuveni

Health policy decisions regarding patient treatment strategies require consideration of both treatment effectiveness and cost. Optimizing treatment rules with respect to effectiveness may result in prohibitively expensive strategies; on the…

统计方法学 · 统计学 2021-10-20 Nicholas Illenberger , Andrew J. Spieker , Nandita Mitra

A dynamic treatment regime is a sequence of medical decisions that adapts to the evolving clinical status of a patient over time. To facilitate personalized care, it is crucial to assess the probability of each available treatment option…

统计方法学 · 统计学 2024-11-05 Jiefeng Bi , Matteo Borrotti , Bernardo Nipoti

In the Home Service Assignment, Routing, and Appointment scheduling (H-SARA) problem, a set of homogeneous service teams must visit a set of customers. The home service provider needs to decide how many teams to hire (i.e., sizing problem),…

最优化与控制 · 数学 2021-09-21 Daniel Yamín , Daniel Barahona , Alfaima L. Solano-Blanco

Problem Definition: Managing inpatient flow in large hospital systems is challenging due to the complexity of assigning randomly arriving patients -- either waiting for primary units or being overflowed to alternative units. Current…

最优化与控制 · 数学 2026-05-08 Jingjing Sun , Jim Dai , Pengyi Shi

The distributed operating room (OR) scheduling problem aims to find an assignment of surgeries to ORs across collaborating hospitals that share their waiting lists and ORs. We propose a stochastic extension of this problem where surgery…

最优化与控制 · 数学 2020-10-06 Cheng Guo , Merve Bodur , Dionne M. Aleman , David R. Urbach

This paper considers the scheduling of stochastic jobs on parallel identical machines to minimize the expected total weighted completion time. While this is a classical problem with a significant body of research on approximation algorithms…

数据结构与算法 · 计算机科学 2026-01-27 Benjamin Moseley , Kirk Pruhs , Marc Uetz , Rudy Zhou

Tanker water systems play critical role in providing adequate service to meet potable water demands in the face of acute water crisis in many cities globally. Managing tanker movements among the supply and demand sides requires an efficient…

In radiation therapy, mathematical methods have been used for optimizing treatment planning for delivery of sufficient dose to the cancerous cells while keeping the dose to critical surrounding structures minimal. This optimization problem…

医学物理 · 物理学 2015-06-16 Hamed Yarmand , David Craft

We propose a hybrid algorithmic strategy for complex stochastic optimization problems, which combines the use of scenario trees from multistage stochastic programming with machine learning techniques for learning a policy in the form of a…

最优化与控制 · 数学 2019-10-25 Boris Defourny , Damien Ernst , Louis Wehenkel

In this paper, we develop mixed integer linear programming models to compute near-optimal policy parameters for the non-stationary stochastic lot sizing problem under Bookbinder and Tan's static-dynamic uncertainty strategy. Our models…

最优化与控制 · 数学 2014-09-18 Roberto Rossi , Onur A. Kilic , S. Armagan Tarim

Purpose: To develop a multi-criteria optimization framework for image guided radiotherapy. Methods: An algorithm is proposed for a multi-criteria framework for the purpose of patient setup verification decision processes. Optimal patient…

医学物理 · 物理学 2011-08-16 Brian Winey , James Balter

Our research has shown that schedules can be built mimicking a human scheduler by using a set of rules that involve domain knowledge. This chapter presents a Bayesian Optimization Algorithm (BOA) for the nurse scheduling problem that…

神经与进化计算 · 计算机科学 2010-07-05 Jingpeng Li , Uwe Aickelin

We develop a quadratic regularization approach for the solution of high-dimensional multistage stochastic optimization problems characterized by a potentially large number of time periods/stages (e.g. hundreds), a high-dimensional resource…

最优化与控制 · 数学 2017-02-28 Tsvetan Asamov , Warren B. Powell

The availability of downstream resources plays is critical in planning the admission of elective surgery patients. The most crucial one is inpatient beds. To ensure bed availability, hospitals may use machine learning (ML) models to predict…

机器学习 · 计算机科学 2025-07-30 Pieter Smet , Martina Doneda , Ettore Lanzarone , Giuliana Carello

Stochastic optimisation algorithms are the de facto standard for machine learning with large amounts of data. Handling only a subset of available data in each optimisation step dramatically reduces the per-iteration computational costs,…

数值分析 · 数学 2024-12-19 Matthias J. Ehrhardt , Zeljko Kereta , Jingwei Liang , Junqi Tang

We consider the problem of scheduling appointments for a finite customer population to a service facility with customer no-shows, to minimize the sum of customer waiting time and server overtime costs. Since appointments need to be…

最优化与控制 · 数学 2017-08-22 Mor Armony , Rami Atar , Harsha Honnappa

This paper introduces a node formulation for multistage stochastic programs with endogenous (i.e., decision-dependent) uncertainty. Problems with such structure arise when the choices of the decision maker determine a change in the…

最优化与控制 · 数学 2021-03-05 Giovanni Pantuso