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Recent advances in transformer architectures have revolutionised natural language processing, but their application to healthcare domains presents unique challenges. Patient timelines are characterised by irregular sampling, variable…

计算与语言 · 计算机科学 2025-05-26 Linglong Qian , Zina Ibrahim

Transformer-based models have improved predictive modeling on longitudinal electronic health records through large-scale self-supervised pretraining. However, most EHR transformer architectures treat each clinical encounter as an unordered…

机器学习 · 计算机科学 2026-03-17 Krish Tadigotla

Objective: In modern healthcare, accurately predicting diseases is a crucial matter. This study introduces a novel approach using graph neural networks (GNNs) and a Graph Transformer (GT) to predict the incidence of heart failure (HF) on a…

机器学习 · 计算机科学 2025-06-23 Heloisa Oss Boll , Ali Amirahmadi , Amira Soliman , Stefan Byttner , Mariana Recamonde-Mendoza

Large clinical datasets derived from insurance claims and electronic health record (EHR) systems are valuable sources for precision medicine research. These datasets can be used to develop models for personalized prediction of risk or…

统计方法学 · 统计学 2021-10-20 Liang Liang , Jue Hou , Hajime Uno , Kelly Cho , Yanyuan Ma , Tianxi Cai

We develop an unsupervised probabilistic model for heterogeneous Electronic Health Record (EHR) data. Utilizing a mixture model formulation, our approach directly models sequences of arbitrary length, such as medications and laboratory…

机器学习 · 计算机科学 2022-09-02 Alan D. Kaplan , John D. Greene , Vincent X. Liu , Priyadip Ray

With the rise of medical foundation models and the growing availability of imaging data, scalable pretraining techniques offer a promising way to identify imaging biomarkers predictive of future disease risk. While current self-supervised…

Deep learning methods exhibit promising performance for predictive modeling in healthcare, but two important challenges remain: -Data insufficiency:Often in healthcare predictive modeling, the sample size is insufficient for deep learning…

机器学习 · 计算机科学 2017-04-04 Edward Choi , Mohammad Taha Bahadori , Le Song , Walter F. Stewart , Jimeng Sun

Chronic kidney disease (CKD) is a significant public health challenge, often progressing to end-stage renal disease (ESRD) if not detected and managed early. Early intervention, warranted by silent disease progression, can significantly…

机器学习 · 计算机科学 2024-11-19 Zachary Dana , Ahmed Ammar Naseer , Botros Toro , Sumanth Swaminathan

Chronic Kidney Disease (CKD) is a major global health issue which is affecting million people around the world and with increasing rate of mortality. Mitigation of progression of CKD and better patient outcomes requires early detection.…

The advent of the Internet era has led to an explosive growth in the Electronic Health Records (EHR) in the past decades. The EHR data can be regarded as a collection of clinical events, including laboratory results, medication records,…

机器学习 · 计算机科学 2019-11-14 Zichang Wang , Haoran Li , Luchen Liu , Haoxian Wu , Ming Zhang

Electronic Health Records (EHR) are high-dimensional data with implicit connections among thousands of medical concepts. These connections, for instance, the co-occurrence of diseases and lab-disease correlations can be informative when…

机器学习 · 计算机科学 2021-03-29 Weicheng Zhu , Narges Razavian

With the increased availability of large databases of electronic health records (EHRs) comes the chance of enhancing health risks screening. Most post-marketing detections of adverse drug reaction (ADR) rely on physicians' spontaneous…

应用统计 · 统计学 2018-01-29 Maryan Morel , Emmanuel Bacry , Stéphane Gaïffas , Agathe Guilloux , Fanny Leroy

The availability of a large amount of electronic health records (EHR) provides huge opportunities to improve health care service by mining these data. One important application is clinical endpoint prediction, which aims to predict whether…

人工智能 · 计算机科学 2018-11-20 Luchen Liu , Jianhao Shen , Ming Zhang , Zichang Wang , Jian Tang

Deep learning-based predictive models, leveraging Electronic Health Records (EHR), are receiving increasing attention in healthcare. An effective representation of a patient's EHR should hierarchically encompass both the temporal…

机器学习 · 计算机科学 2024-05-08 Jiayuan Chen , Changchang Yin , Yuanlong Wang , Ping Zhang

Early detection of Alzheimer's disease (AD) is crucial because its neurodegenerative effects are irreversible, and neuropathologic and social-behavioral risk factors accumulate years before diagnosis. Identifying higher-risk individuals…

机器学习 · 计算机科学 2025-10-14 Xi Mao , Zhendong Wang , Jingyu Li , Lingchao Mao , Utibe Essien , Hairong Wang , Xuelei Sherry Ni

Acute kidney injury (AKI) commonly occurs in hospitalized patients and can lead to serious medical complications. In order to optimally predict AKI before it develops at any time during a hospital stay, we present a novel framework in which…

定量方法 · 定量生物学 2019-02-28 Rohit J. Kate , Noah Pearce , Debesh Mazumdar , Vani Nilakantan

The era of big data has made vast amounts of clinical data readily available, particularly in the form of electronic health records (EHRs), which provides unprecedented opportunities for developing data-driven diagnostic tools to enhance…

机器学习 · 计算机科学 2025-03-06 Zekai Wang , Tieming Liu , Bing Yao

Increasing volume of Electronic Health Records (EHR) in recent years provides great opportunities for data scientists to collaborate on different aspects of healthcare research by applying advanced analytics to these EHR clinical data. A…

机器学习 · 计算机科学 2019-10-01 Najibesadat Sadati , Milad Zafar Nezhad , Ratna Babu Chinnam , Dongxiao Zhu

Wearable sensor based human activity recognition is a challenging problem due to difficulty in modeling spatial and temporal dependencies of sensor signals. Recognition models in closed-set assumption are forced to yield members of known…

计算机视觉与模式识别 · 计算机科学 2024-04-24 M Tanjid Hasan Tonmoy , Saif Mahmud , A K M Mahbubur Rahman , M Ashraful Amin , Amin Ahsan Ali

Traditional diagnosis of chronic diseases involves in-person consultations with physicians to identify the disease. However, there is a lack of research focused on predicting and developing application systems using clinical notes and blood…

软件工程 · 计算机科学 2024-06-27 Chun-Chieh Liao , Wei-Ting Kuo , I-Hsuan Hu , Yen-Chen Shih , Jun-En Ding , Feng Liu , Fang-Ming Hung