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Family history is considered a risk factor for many diseases because it implicitly captures shared genetic, environmental and lifestyle factors. Finland's nationwide electronic health record (EHR) system spanning multiple generations…

应用统计 · 统计学 2024-03-08 Sophie Wharrie , Zhiyu Yang , Andrea Ganna , Samuel Kaski

To overcome the limitations of manual administrative coding in geriatric Cardiovascular Risk Management, this study introduces an automated classification framework leveraging unstructured Electronic Health Records (EHRs). Using a dataset…

The increased adoption of Electronic Health Records(EHRs) has brought changes to the way the patient care is carried out. The rich heterogeneous and temporal data space stored in EHRs can be leveraged by machine learning models to capture…

机器学习 · 计算机科学 2019-04-11 Maria Bampa

Successful health risk prediction demands accuracy and reliability of the model. Existing predictive models mainly depend on mining electronic health records (EHR) with advanced deep learning techniques to improve model accuracy. However,…

机器学习 · 计算机科学 2021-04-27 Chacha Chen , Junjie Liang , Fenglong Ma , Lucas M. Glass , Jimeng Sun , Cao Xiao

The breadth, scale, and temporal granularity of modern electronic health records (EHR) systems offers great potential for estimating personalized and contextual patient health trajectories using sequential deep learning. However, learning…

Heart failure (HF) is a major cause of mortality. Accurately monitoring HF progress and adjust therapies are critical for improving patient outcomes. An experienced cardiologist can make accurate HF stage diagnoses based on combination of…

机器学习 · 计算机科学 2021-03-23 Shuyu Lu , Ruoyu Chen , Wei Wei , Xinghua Lu

The self-attention mechanism, which equips with a strong capability of modeling long-range dependencies, is one of the extensively used techniques in the sequential recommendation field. However, many recent studies represent that current…

信息检索 · 计算机科学 2023-05-18 Xinyu Du , Huanhuan Yuan , Pengpeng Zhao , Jianfeng Qu , Fuzhen Zhuang , Guanfeng Liu , Victor S. Sheng

This paper introduces an innovative Electronic Health Record (EHR) foundation model that integrates Polygenic Risk Scores (PRS) as a foundational data modality, moving beyond traditional EHR-only approaches to build more holistic health…

The temporal complexity of electronic health record (EHR) data presents significant challenges for predicting clinical outcomes using machine learning. This paper proposes ChronoFormer, an innovative transformer based architecture…

机器学习 · 计算机科学 2025-04-11 Yuanyun Zhang , Shi Li

Single-cell RNA sequencing (scRNA-seq) has revolutionized biological discovery, providing an unbiased picture of cellular heterogeneity in tissues. While scRNA-seq has been used extensively to provide insight into both healthy systems and…

基因组学 · 定量生物学 2020-03-16 Neal G. Ravindra , Arijit Sehanobish , Jenna L. Pappalardo , David A. Hafler , David van Dijk

Sepsis is a life-threatening condition that seriously endangers millions of people over the world. Hopefully, with the widespread availability of electronic health records (EHR), predictive models that can effectively deal with clinical…

机器学习 · 计算机科学 2019-10-16 Luchen Liu , Haoxian Wu , Zichang Wang , Zequn Liu , Ming Zhang

Learning from longitudinal electronic health records is limited if it does not capture the temporal trajectories of the patient's state in a clinical setting. Graph models allow us to capture the hidden dependencies of the multivariate…

机器学习 · 计算机科学 2025-03-31 Munib Mesinovic , Soheila Molaei , Peter Watkinson , Tingting Zhu

Electronic healthcare records (EHR) contain a huge wealth of data that can support the prediction of clinical outcomes. EHR data is often stored and analysed using clinical codes (ICD10, SNOMED), however these can differ across registries…

机器学习 · 计算机科学 2024-12-03 Elizabeth Remfry , Rafael Henkin , Michael R Barnes , Aakanksha Naik

In critical care, intensivists are required to continuously monitor high dimensional vital signs and lab measurements to detect and diagnose acute patient conditions. This has always been a challenging task. In this study, we propose a…

机器学习 · 计算机科学 2019-01-15 Ziyuan Pan , Hao Du , Kee Yuan Ngiam , Fei Wang , Ping Shum , Mengling Feng

Disease progression models are widely used to inform the diagnosis and treatment of many progressive diseases. However, a significant limitation of existing models is that they do not account for health disparities that can bias the…

机器学习 · 计算机科学 2025-05-01 Erica Chiang , Divya Shanmugam , Ashley N. Beecy , Gabriel Sayer , Deborah Estrin , Nikhil Garg , Emma Pierson

Massive electronic health records (EHRs) enable the success of learning accurate patient representations to support various predictive health applications. In contrast, doctor representation was not well studied despite that doctors play…

机器学习 · 计算机科学 2019-11-26 Siddharth Biswal , Cao Xiao , Lucas M. Glass , Elizabeth Milkovits , Jimeng Sun

Deep learning models exhibit state-of-the-art performance for many predictive healthcare tasks using electronic health records (EHR) data, but these models typically require training data volume that exceeds the capacity of most healthcare…

机器学习 · 计算机科学 2018-10-24 Edward Choi , Cao Xiao , Walter F. Stewart , Jimeng Sun

Clinical prediction from structured electronic health records (EHRs) is challenging due to high dimensionality, heterogeneity, class imbalance, and distribution shift. While tabular in-context learning (TICL) and retrieval-augmented methods…

In this paper we study the problem of predicting clinical diagnoses from textual Electronic Health Records (EHR) data. We show the importance of this problem in medical community and present comprehensive historical review of the problem…

计算与语言 · 计算机科学 2020-09-29 Pavel Blinov , Manvel Avetisian , Vladimir Kokh , Dmitry Umerenkov , Alexander Tuzhilin

Early detection of chronic diseases is beneficial to healthcare by providing a golden opportunity for timely interventions. Although numerous prior studies have successfully used machine learning (ML) models for disease diagnoses, they…

计算机与社会 · 计算机科学 2024-10-07 Di Wang , Yidan Hu , Eng Sing Lee , Hui Hwang Teong , Ray Tian Rui Lai , Wai Han Hoi , Chunyan Miao