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Criticality can be exactly demonstrated in certain models of brain activity, yet it remains challenging to identify in empirical data. We trained a fully connected deep neural network to learn the phases of an excitable model unfolding on…

神经元与认知 · 定量生物学 2022-06-13 Hernan Bocaccio , Enzo Tagliazucchi

Neural circuits are able to perform computations under very diverse conditions and requirements. The required computations impose clear constraints on their fine-tuning: a rapid and maximally informative response to stimuli in general…

The relation between large-scale brain structure and function is an outstanding open problem in neuroscience. We approach this problem by studying the dynamical regime under which realistic spatio-temporal patterns of brain activity emerge…

神经元与认知 · 定量生物学 2014-05-27 Ariel Haimovici , Enzo Tagliazucchi , Pablo Balenzuela , Dante R. Chialvo

Dynamic functional connectivity (DFC) analysis has been widely applied to functional magnetic resonance imaging (fMRI) data to reveal time-varying dynamic changes of brain states. The sliding window method is by far the most popular DFC…

机器学习 · 计算机科学 2024-11-07 Yongjie Duan , Vince D. Calhoun , Zhiying Long

Being permanently confronted with an uncertain world, brains have faced evolutionary pressure to represent this uncertainty in order to respond appropriately. Often, this requires visiting multiple interpretations of the available…

Neural computation is associated with the emergence, reconfiguration and dissolution of cell assemblies in the context of varying oscillatory states. Here, we describe the complex spatio-temporal dynamics of cell assemblies through temporal…

神经元与认知 · 定量生物学 2020-01-20 Nicola Pedreschi , Christophe Bernard , Wesley Clawson , Pascale Quilichini , Alain Barrat , Demian Battaglia

Demystifying effective connectivity among neuronal populations has become the trend to understand the brain mechanisms of Parkinson's disease, schizophrenia, mild traumatic brain injury, and many other unlisted neurological diseases.…

定量方法 · 定量生物学 2019-09-27 Po-Ya Hsu

Complex functional brain network analyses have exploded over the last eight years, gaining traction due to their profound clinical implications. The application of network science (an interdisciplinary offshoot of graph theory) has…

统计方法学 · 统计学 2013-10-28 Sean L. Simpson , F. DuBois Bowman , Paul J. Laurienti

The experimental study of neural networks requires simultaneous measurements of a massive number of neurons, while monitoring properties of the connectivity, synaptic strengths and delays. Current technological barriers make such a mission…

神经元与认知 · 定量生物学 2016-01-12 Amir Goldental , Pinhas Sabo , Shira Sardi , Roni Vardi , Ido Kanter

Artificial neural networks built from two-state neurons are powerful computational substrates, whose computational ability is well understood by analogy with statistical mechanics. In this work, we introduce similar analogies in the context…

神经与进化计算 · 计算机科学 2010-09-29 Paul Merolla , Tristan Ursell , John Arthur

The functional computation of the human brain arises from the collective behaviour of the underlying neural network. The emerging technology enables the recording of population activity in neurons, and the theory of neural networks is…

生物物理 · 物理学 2025-08-29 Yoshiaki Horiike , Shin Fujishiro

Whole-brain computational modeling based on structural connectivity has shown great promise in successfully simulating fMRI BOLD signals with temporal co-activation patterns that are highly similar to empirical functional connectivity…

神经元与认知 · 定量生物学 2019-11-14 Neda Kaboodvand , Martijn P van den Heuvel , Peter Fransson

To understand how neural networks process information, it is important to investigate how neural network dynamics varies with respect to different stimuli. One challenging task is to design efficient statistical approaches to analyze…

神经元与认知 · 定量生物学 2018-11-30 Zhi-Qin John Xu , Douglas Zhou , David Cai

The Neural Tangent Kernel (NTK) offers a powerful tool to study the functional dynamics of neural networks. In the so-called lazy, or kernel regime, the NTK remains static during training and the network function is linear in the static…

机器学习 · 计算机科学 2025-07-28 Yuzhi Liu , Zixuan Chen , Zirui Zhang , Yufei Liu , Giulia Lanzillotta

Identifying the spatio-temporal network structure of brain activity from multi-neuronal data streams is one of the biggest challenges in neuroscience. Repeating patterns of precisely timed activity across a group of neurons is potentially…

神经元与认知 · 定量生物学 2009-03-03 Casey Diekman , Kohinoor Dasgupta , Vijay Nair , P. S. Sastry , K. P. Unnikrishnan

Contemporary neuroscience has embraced network science to study the complex and self-organized structure of the human brain; one of the main outstanding issues is that of inferring from measure data, chiefly functional Magnetic Resonance…

最优化与控制 · 数学 2017-03-31 Giulia Prando , Mattia Zorzi , Alessandra Bertoldo , Alessandro Chiuso

Most generally, dynamic functional connectivity (FC) refers to the non-instantaneous couplings across timeseries from a set of brain areas, here as measured by fMRI. This is in contrast to static FC, which is defined as purely instantaneous…

神经元与认知 · 定量生物学 2023-01-10 Christine Ahrends , Diego Vidaurre

The relative timing of action potentials in neurons recorded from local cortical networks often shows a non-trivial dependence, which is then quantified by cross-correlation functions. Theoretical models emphasize that such spike train…

神经元与认知 · 定量生物学 2017-06-28 Taskin Deniz , Stefan Rotter

Networks constitute fundamental organizational structures across biological systems, although conventional graph-theoretic analyses capture exclusively pairwise interactions, thereby omitting the intricate higher-order relationships that…

定量方法 · 定量生物学 2025-12-23 Sixtus Dakurah

Global brain activity self-organizes into discrete patterns characterized by distinct behavioral observables and modes of information processing. The human thalamocortical system is a densely connected network where local neural activation…