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While most classic studies of function in experimental neuroscience have focused on the coding properties of individual neurons, recent developments in recording technologies have resulted in an increasing emphasis on the dynamics of neural…

机器学习 · 计算机科学 2021-11-02 Anne Draelos , Pranjal Gupta , Na Young Jun , Chaichontat Sriworarat , John Pearson

To understand possible strategies of temporal spike coding in the central nervous system, we study functional neuromimetic models of visual processing for static images. We will first present the retinal model which was introduced by Van…

神经元与认知 · 定量生物学 2007-05-23 Laurent Perrinet , Manuel Samuelides , Simon Thorpe

Understanding the functioning of a neural system in terms of its underlying circuitry is an important problem in neuroscience. Recent developments in electrophysiology and imaging allow one to simultaneously record activities of hundreds of…

数据库 · 计算机科学 2008-03-11 Debprakash Patnaik , P. S. Sastry , K. P. Unnikrishnan

This paper studies change-points in human brain functional connectivity (FC) and seeks patterns that are common across multiple subjects under identical external stimulus. FC relates to the similarity of fMRI responses across different…

神经元与认知 · 定量生物学 2020-03-05 Mengyu Dai , Zhengwu Zhang , Anuj Srivastava

Understanding how the brain learns to compute functions reliably, efficiently and robustly with noisy spiking activity is a fundamental challenge in neuroscience. Most sensory and motor tasks can be described as dynamical systems and could…

神经元与认知 · 定量生物学 2017-05-24 Sophie Denève , Alireza Alemi , Ralph Bourdoukan

In the last century, most sensorimotor studies of cortical neurons relied on average firing rates. Rate coding is efficient for fast sensorimotor processing that occurs within a few seconds. Much less is known about the neural mechanisms…

神经元与认知 · 定量生物学 2026-05-01 Terrence J. Sejnowski

Human creativity originates from brain cortical networks that are specialized in idea generation, processing, and evaluation. The concurrent verbalization of our inner thoughts during the execution of a design task enables the use of…

计算与语言 · 计算机科学 2025-01-22 Danko D. Georgiev , Georgi V. Georgiev

We propose a hierarchically modular, dynamical neural network model whose architecture minimizes a specifically designed energy function and defines its temporal characteristics. The model has an internal and an external space that are…

神经元与认知 · 定量生物学 2026-04-16 Kazuyoshi Tsutsumi , Ernst Niebur

Functional magnetic resonance imaging (fMRI) technology is popularly used in many fields for studying how the brain reacts to mental stimuli. The identification of optimal fMRI experimental designs is crucial for rendering precise…

统计理论 · 数学 2015-10-30 Ching-Shui Cheng , Ming-Hung Kao

We conduct an imaging genetics study to explore how effective brain connectivity in the default mode network (DMN) may be related to genetics within the context of Alzheimer's disease and mild cognitive impairment. We develop an analysis of…

There is growing interest in understanding how the structural interconnections among brain regions change with the occurrence of neurological diseases. Diffusion weighted MRI imaging has allowed researchers to non-invasively estimate a…

应用统计 · 统计学 2015-10-20 Daniele Durante , Madelaine Daianu , Neda Jahanshad , Paul M. Thompson , David B. Dunson

Synaptic plasticity and neuron cross-talk are some of the important key mechanisms underlying formation of dynamic clusters of active neurons. The essence of this study is to model and decipher the mechanism of emergence of a task-specific…

神经元与认知 · 定量生物学 2021-08-03 Jasleen Gund , R. K. Brojen Singh

Simultaneous behavioral and electrophysiological recordings call for new methods to reveal the interactions between neural activity and behavior. A milestone would be an interpretable model of the co-variability of spiking activity and…

神经元与认知 · 定量生物学 2023-12-04 Christos Sourmpis , Carl Petersen , Wulfram Gerstner , Guillaume Bellec

Causal relations among neuronal populations of the brain are studied through the so-called effective connectivity (EC) network. The latter is estimated from EEG or fMRI measurements, by inverting a generative model of the corresponding…

系统与控制 · 计算机科学 2018-02-16 Giulia Prando , Mattia Zorzi , Alessandra Bertoldo , Alessandro Chiuso

The co-occurrence of action potentials of pairs of neurons within short time intervals is known since long. Such synchronous events can appear time-locked to the behavior of an animal and also theoretical considerations argue for a…

神经元与认知 · 定量生物学 2022-05-17 Moritz Helias , Tom Tetzlaff , Markus Diesmann

Dynamic models of signaling networks allow the formulation of hypotheses on the topology and kinetic rate laws characterizing a given molecular network, in-depth exploration and confrontation with kinetic biological data. Despite its…

How the information microscopically processed by individual neurons is integrated and used in organizing the behavior of an animal is a central question in neuroscience. The coherence of neuronal dynamics over different scales has been…

无序系统与神经网络 · 物理学 2020-03-11 Takashi Hayakawa , Tomoki Fukai

Emerging technologies and applications make the network unprecedentedly complex and heterogeneous, leading physical network practices to be costly and risky. The digital twin network (DTN) can ease these burdens by virtually enabling users…

网络与互联网体系结构 · 计算机科学 2022-06-02 Linbo Hui , Mowei Wang , Liang Zhang , Lu Lu , Yong Cui

Data-driven brain parcellations aim to provide a more accurate representation of an individual's functional connectivity, since they are able to capture individual variability that arises due to development or disease. This renders…

神经元与认知 · 定量生物学 2017-03-30 Sofia Ira Ktena , Salim Arslan , Sarah Parisot , Daniel Rueckert

Cross-correlations in the activity in neural networks are commonly used to characterize their dynamical states and their anatomical and functional organizations. Yet, how these latter network features affect the spatiotemporal structure of…

神经元与认知 · 定量生物学 2018-09-26 Ran Darshan , Carl van Vreeswijk , David Hansel
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