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An adjoint-based shape optimization method for solid bodies subjected to both rarefied and continuum gas flows is proposed. The gas-kinetic BGK equation with the diffuse-reflection boundary condition is used to describe the multiscale gas…

计算物理 · 物理学 2025-01-03 Ruifeng Yuan , Lei Wu

Numerical simulations of cardiovascular mass transport pose significant challenges due to the wide range of P\'eclet numbers and backflow at Neumann boundaries. In this paper we present and discuss several numerical tools to address these…

Control flow graphs (CFGs) are essential tools for understanding program behavior, yet the size of real-world CFGs makes them difficult to interpret. With thousands of nodes and edges, sophisticated graph drawing algorithms are required to…

人机交互 · 计算机科学 2025-11-10 Philipp Schaad , Tal Ben-Nun , Torsten Hoefler

We address the problem of controlling Connected and Automated Vehicles (CAVs) in conflict areas of a traffic network subject to hard safety constraints. It has been shown that such problems can be solved through a combination of tractable…

机器人学 · 计算机科学 2023-06-06 Ehsan Sabouni , H. M. Sabbir Ahmad , Wei Xiao , Christos G. Cassandras , Wenchao Li

Connected and automated vehicle (CAV) technology is providing urban transportation managers tremendous opportunities for better operation of urban mobility systems. However, there are significant challenges in real-time implementation, as…

最优化与控制 · 数学 2020-10-13 Xi Lin , Meng Li , Zuo-jun Max Shen , Yafeng Yin , Fang He

This article concerns the problem of computing solutions to state-constrained optimal control problems whose trajectory is affected by a flow field. This general mathematical framework is particularly pertinent to the requirements…

最优化与控制 · 数学 2022-06-30 Roman Chertovskih , Nathalie T. Khalil , Dmitry Karamzin , Fernando Lobo Pereira

Cardiovascular disease affects millions of people worldwide and its social and economic cost clearly motivates scientific research. Computer simulation can lead to a better understanding of cardiac physiology, and for pathology presents…

生物物理 · 物理学 2023-02-27 Toby Simpson

Numerical simulations are a valuable research and layout tool for fluid flow problems, yet repeated evaluations of parametrized problems, necessary to solve optimization problems, can be very costly. One option to speed up this process is…

流体动力学 · 物理学 2025-02-28 Marian Staggl , Wolfgang Sanz , Paul Pieringer

There has been intensive work on the parameterized complexity of the typically NP-hard task to edit undirected graphs into graphs fulfilling certain given vertex degree constraints. In this work, we lift the investigations to the case of…

Strokes are still one of the leading causes for death after heart diseases and cancer in all over the world. Most strokes happen because an artery that carries blood uphill from the heart to the head gets clogged. Most of the time, as with…

组织与器官 · 定量生物学 2020-02-03 Nurullah Arslan , Kazim Besirli , Gurcan Comert , Omer F Beyca

This work develops a rigorous numerical framework for solving time-dependent Optimal Control Problems (OCPs) governed by partial differential equations, with a particular focus on biomedical applications. The approach deals with…

Computational Fluid Dynamics (CFD) is used to assist in designing artificial valves and planning procedures, focusing on local flow features. However, assessing the impact on overall cardiovascular function or predicting longer-term…

High-fidelity control of qubits requires precisely tuned control parameters. Typically, these parameters are found through a series of bootstrapped calibration experiments which successively acquire more accurate information about a…

量子物理 · 物理学 2018-03-09 Julian Kelly , Peter O'Malley , Matthew Neeley , Hartmut Neven , John M. Martinis

Aiming at the limitations of traditional medical decision system in processing large-scale heterogeneous medical data and realizing highly personalized recommendation, this paper introduces a personalized medical decision algorithm…

机器学习 · 计算机科学 2024-05-29 Yafeng Yan , Shuyao He , Zhou Yu , Jiajie Yuan , Ziang Liu , Yan Chen

We present a real-time safety filter for motion planning, including those that are learning-based, using Control Barrier Functions (CBFs) to provide formal guarantees for collision avoidance with road boundaries. A key feature of our…

机器人学 · 计算机科学 2026-03-25 Jianye Xu , Chang Che , Bassam Alrifaee

A data-driven Reduced Order Model (ROM) based on a Proper Orthogonal Decomposition - Radial Basis Function (POD-RBF) approach is adopted in this paper for the analysis of blood flow dynamics in a patient-specific case of Atrial Fibrillation…

Through legislation and technical advances users gain more control over how their data is processed, and they expect online services to respect their privacy choices and preferences. However, data may be processed for many different…

数据库 · 计算机科学 2024-03-19 Dorota Filipczuk , Enrico H. Gerding , George Konstantinidis

Blood flow imaging provides important information for hemodynamic behavior within the vascular system and plays an essential role in medical diagnosis and treatment planning. However, obtaining high-quality flow images remains a significant…

数值分析 · 数学 2026-04-02 Han Zhang , Xue-Cheng Tai , Jean-Michel Morel , Raymond H. Chan

Clinical pathways outline standardized processes in the delivery of care for a specific disease. Patient journeys through the healthcare system, though, can deviate substantially from these pathways. Given the positive benefits of clinical…

Diffusion and flow-matching have emerged as powerful methodologies for generative modeling, with remarkable success in capturing complex data distributions and enabling flexible guidance at inference time. Many downstream applications,…

机器学习 · 计算机科学 2026-04-28 Zeyang Li , Kaveh Alim , Navid Azizan