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相关论文: Robustness of FCS (Fluorescence Correlation Spectr…

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Fluorescence Correlation Spectroscopy (FCS) is widely used to detect and quantify diffusion processes at the molecular level. The molecules of which diffusion is studied are marked with fluorescent dyes. It is commonly maintained that this…

生物物理 · 物理学 2018-06-12 Mathias Lechelon , Marco Pettini

The random motion of molecules in living cells has consistently been reported to deviate from standard Brownian motion, a behavior coined as ``anomalous diffusion''. Fluorescence Correlation Spectroscopy (FCS) is a powerful method to…

We present a new method that combines fluorescence correlation spectroscopy (FCS) on the microsecond time scale with fluorescence antibunching measurements on the nanosecond time scale for measuring photophysical rate constants of…

化学物理 · 物理学 2022-03-28 Damir Sakhapov , Ingo Gregor , Narain Karedla , Jörg Enderlein

Fluorescence Correlation Spectroscopy (FCS) is a powerful single-molecule technique which allows for measuring motion (diffusion, flow), concentration, and molecular interaction kinetics of fluorescent molecules from picomolar to micromolar…

We present a comprehensive investigation of polymer diffusion in the semidilute regime by fluorescence correlation spectroscopy (FCS) and dynamic light scattering (DLS). Using single-labeled polystyrene chains, FCS leads to the…

We derive the statistics of the signals generated by shape fluctuations of large molecules studied by feedback tracking microscopy. We account for the influence of intramolecular dynamics on the response of the tracking system, and derive a…

光学 · 物理学 2015-05-13 Kevin McHale , Hideo Mabuchi

A continuous time random walk (CTRW) model with waiting times following the Levy-stable distribution with exponential cut-off in equilibrium is a simple theoretical model giving rise to normal, yet non-Gaussian diffusion. The distribution…

数据分析、统计与概率 · 物理学 2017-05-31 S. M. J. Khadem , I. M. Sokolov

Fluorescence Correlation Spectroscopy (FCS) yields measurement parameters (number of molecules, diffusion time) that characterize the concentration and kinetics of fluorescent molecules within a supposedly known observation volume. Absolute…

生物物理 · 物理学 2011-12-23 Charles Edouard Leroux , Irène Wang , Jacques Derouard , Antoine Delon

Diffusion of tracer dye molecules in water confined to nanoscale is an important subject with a direct bearing on many technological applications. It is not yet clear however, if the dynamics of water in hydrophilic as well as hydrophobic…

软凝聚态物质 · 物理学 2022-01-19 Shivprasad Patil , V. J. Ajith

Many cell signaling pathways involve the diffusion of messengers that bind/unbind to intracellular components. Quantifying their net transport rate under different conditions, then requires having separate estimates of their free diffusion…

亚细胞过程 · 定量生物学 2017-06-21 Lorena Sigaut , Cecilia Villarruel , María Laura Ponce , Silvina Ponce Dawson

Light emission from solid-state quantum emitters is inherently prone to environmental decoherence, which results in an inhomogeneous line broadening and in the deterioration of photon indistinguishability. Here we employ photon correlation…

The role of disorder on physical systems has been widely studied in the macroscopic and microscopic world. While static disorder is well understood in many cases, the impact of time-dependent disorder on quantum gases is still poorly…

量子气体 · 物理学 2024-01-26 Silvia Hiebel , Benjamin Nagler , Sian Barbosa , Jennifer Koch , Artur Widera

Diffuse correlation spectroscopy (DCS) is an emerging noninvasive technique that measures the tissue blood flow, by using near-infrared coherent point-source illumination to detect spectral changes. While machine learning has demonstrated…

机器学习 · 计算机科学 2024-02-02 Xi Chen , Xingda Li

Ultrafast spectroscopy is an emerging technique with great promise in the study of quantum materials, as it makes it possible to track similarities and correlations that are not evident near equilibrium. Thus far, however, the way in which…

Determining the number of fluorescent entities that are coupled to a given molecule (DNA, protein, etc.) is a key point of numerous biological studies, especially those based on a single molecule approach. Reliable methods are important, in…

Graphene's fluorescence quenching is studied as a function of distance. Transverse decay channels, full retardation and graphene-field coupling to all orders are included, extending previous instantaneous results. For neutral graphene, a…

介观与纳米尺度物理 · 物理学 2011-11-03 G. Gómez-Santos , T. Stauber

The diffusion of macromolecules in cells and in complex fluids is often found to deviate from simple Fickian diffusion. One explanation offered for this behavior is that molecular crowding renders diffusion anomalous, where the mean-squared…

软凝聚态物质 · 物理学 2016-05-18 Daniel S. Banks , Charmaine Tressler , Robert D. Peters , Felix Höfling , Cécile Fradin

The application of diffusion transformers is suffering from their significant inference costs. Recently, feature caching has been proposed to solve this problem by reusing features from previous timesteps, thereby skipping computation in…

In this article, we analyze different factors that affect the diffusion behavior of small tracer particles (as they are used e.g.in fluorescence correlation spectroscopy (FCS)) in the polymer network of a hydrogel and perform simulations of…

软凝聚态物质 · 物理学 2011-03-15 Fatemeh Tabatabaei , Olaf Lenz , Christian Holm

A ubiquitous observation in crowded cell membranes is that molecular transport does not follow Fickian diffusion but exhibits subdiffusion. The microscopic origin of such a behaviour is not understood and highly debated. Here we discuss the…

软凝聚态物质 · 物理学 2011-02-15 Felix Höfling , Karl-Ulrich Bamberg , Thomas Franosch
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