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Diffusion models have had a profound impact on many application areas, including those where data are intrinsically infinite-dimensional, such as images or time series. The standard approach is first to discretize and then to apply…

机器学习 · 统计学 2025-06-09 Jakiw Pidstrigach , Youssef Marzouk , Sebastian Reich , Sven Wang

Pyrosequencing is emerging as one of the important next-generation sequencing technologies. We derive the statistical distributions of this technique in terms of nucleotide probabilities of the target sequences. We give exact distributions…

基因组学 · 定量生物学 2024-05-28 Yong Kong

Recent advances in computer vision have shown promising results in image generation. Diffusion probabilistic models in particular have generated realistic images from textual input, as demonstrated by DALL-E 2, Imagen and Stable Diffusion.…

We consider the analysis of high dimensional data given in the form of a matrix with columns consisting of observations and rows consisting of features. Often the data is such that the observations do not reside on a regular grid, and the…

机器学习 · 统计学 2017-08-22 Gal Mishne , Ronen Talmon , Israel Cohen , Ronald R. Coifman , Yuval Kluger

Many mathematical modelling tasks (such as in Economics and Finance) are informed by data that is "found" rather than being the result of carefully designed experiments. This often results in data series that are short, noisy,…

数学软件 · 计算机科学 2025-11-18 Stephen Wright , Colin Paterson

We developed a novel direct algorithm to derive the mass-ratio distribution (MRD) of short-period binaries from an observed sample of single-lined spectroscopic binaries (SB1). The algorithm considers a class of parameterized MRDs and finds…

天体物理仪器与方法 · 物理学 2017-10-18 Sahar Shahaf , Tsevi Mazeh , Simchon Faigler

We derive an efficient stochastic algorithm for inverse problems that present an unknown linear forcing term and a set of nonlinear parameters to be recovered. It is assumed that the data is noisy and that the linear part of the problem is…

数值分析 · 数学 2019-09-17 Darko Volkov

Elliptical distribution is a basic assumption underlying many multivariate statistical methods. For example, in sufficient dimension reduction and statistical graphical models, this assumption is routinely imposed to simplify the data…

统计理论 · 数学 2024-12-16 Yin Tang , Bing Li

The aim of this paper is to discuss both higher-order asymptotic expansions and skewed approximations for the Bayesian Discrepancy Measure for testing precise statistical hypotheses. In particular, we derive results on third-order…

统计方法学 · 统计学 2025-05-02 Elena Bortolato , Francesco Bertolino , Monica Musio , Laura Ventura

Visual microscopic study of diseased tissue by pathologists has been the cornerstone for cancer diagnosis and prognostication for more than a century. Recently, deep learning methods have made significant advances in the analysis and…

图像与视频处理 · 电气工程与系统科学 2022-09-30 Puria Azadi Moghadam , Sanne Van Dalen , Karina C. Martin , Jochen Lennerz , Stephen Yip , Hossein Farahani , Ali Bashashati

Construction of a scaffold structure that supports a desired motif, conferring protein function, shows promise for the design of vaccines and enzymes. But a general solution to this motif-scaffolding problem remains open. Current…

生物大分子 · 定量生物学 2023-03-21 Brian L. Trippe , Jason Yim , Doug Tischer , David Baker , Tamara Broderick , Regina Barzilay , Tommi Jaakkola

Typical success-rate prediction models for tapping exclude targets near screen edges; however, design constraints often force such placements. Additionally, in scrollable UIs any element can move close to an edge. In this work, we model how…

人机交互 · 计算机科学 2026-02-27 Nobuhito Kasahara , Shota Yamanaka , Homei Miyashita

We introduce the \textsc{Tailed-Uniform} proposal distribution for generating training simulations in simulation-based inference. Instead of sampling parameters uniformly within bounded regions, we extend the distribution beyond prior…

天体物理仪器与方法 · 物理学 2026-01-27 Chaipat Tirapongprasert , Matthew Ho

Protein design with desirable properties has been a significant challenge for many decades. Generative artificial intelligence is a promising approach and has achieved great success in various protein generation tasks. Notably, diffusion…

The transversity distribution for $u$ and $d$ quarks is usually extracted from data on spin asymmetries in Semi Inclusive Deep Inelastic Scattering (SIDIS): however, due to its chiral odd nature, it has to be coupled to another chiral odd…

高能物理 - 唯象学 · 物理学 2020-11-18 M. Anselmino , R. Kishore , A. Mukherjee

The hierarchical and recursive expressive capability of rooted trees is applicable to represent statistical models in various areas, such as data compression, image processing, and machine learning. On the other hand, such hierarchical…

机器学习 · 计算机科学 2022-01-25 Yuta Nakahara , Shota Saito , Akira Kamatsuka , Toshiyasu Matsushima

The assumption of normality in data has been considered in the field of statistical analysis for a long time. However, in many practical situations, this assumption is clearly unrealistic. It has recently been suggested that the use of…

统计计算 · 统计学 2016-11-25 Reinaldo B. Arellano-Valle , Javier E. Contreras-Reyes

A significant obstacle in the development of robust machine learning models is covariate shift, a form of distribution shift that occurs when the input distributions of the training and test sets differ while the conditional label…

机器学习 · 统计学 2021-11-17 Nilesh Tripuraneni , Ben Adlam , Jeffrey Pennington

This work proposes a statistical model for crossover trials with multiple skewed responses measured in each period. A 3 $\times$ 3 crossover trial data where different drug doses were administered to subjects with a history of seasonal…

统计方法学 · 统计学 2026-04-09 Savita Pareek , Kalyan Das , Siuli Mukhopadhyay

Skewed probit regression is but one example of a statistical model that generalizes a simpler model, like probit regression. All skew-symmetric distributions and link functions arise from symmetric distributions by incorporating a skewness…

统计方法学 · 统计学 2020-09-22 Janet van Niekerk , Haavard Rue