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Despite decades of clinical research, sepsis remains a global public health crisis with high mortality, and morbidity. Currently, when sepsis is detected and the underlying pathogen is identified, organ damage may have already progressed to…
Sepsis, characterized by a dysregulated immune response to infection, results in significant mortality, morbidity, and healthcare costs. The timely prediction of sepsis progression is crucial for reducing adverse outcomes through early…
Sepsis is a life-threatening host response to infection associated with high mortality, morbidity, and health costs. Its management is highly time-sensitive since each hour of delayed treatment increases mortality due to irreversible organ…
Sepsis is a life threatening medical condition that occurs when the body has an extreme response to infection, leading to widespread inflammation, organ failure, and potentially death. Because sepsis can worsen rapidly, early detection is…
Sepsis is a life-threatening condition that requires rapid detection and treatment to prevent progression to severe sepsis, septic shock, or multi-organ failure. Despite advances in medical technology, it remains a major challenge for…
Sepsis is the leading cause of death in non-coronary intensive care units. Moreover, a delay of antibiotic treatment of patients with severe sepsis by only few hours is associated with increased mortality. This insight makes accurate models…
The disease trajectory for clinical sepsis, in terms of temporal cytokine and phenotypic dynamics, can be interpreted as a random dynamical system. The ability to make accurate predictions about patient state from clinical measurements has…
Sepsis is a poorly understood and potentially life-threatening complication that can occur as a result of infection. Early detection and treatment improves patient outcomes, and as such it poses an important challenge in medicine. In this…
Sepsis is a life-threatening condition affecting over 48.9 million people globally and causing 11 million deaths annually. Despite medical advancements, predicting sepsis remains a challenge due to non-specific symptoms and complex…
Sepsis poses a major global health threat, accounting for millions of deaths annually and significant economic costs. Accurately predicting the risk of mortality in sepsis patients enables early identification, promotes the efficient…
We study multiple rule-based and machine learning (ML) models for sepsis detection. We report the first neural network detection and prediction results on three categories of sepsis. We have used the retrospective Medical Information Mart…
Sepsis is a life-threatening disease with high morbidity, mortality and healthcare costs. The early prediction and administration of antibiotics and intravenous fluids is considered crucial for the treatment of sepsis and can save…
Sepsis is a life-threatening organ malfunction caused by the host's inability to fight infection, which can lead to death without proper and immediate treatment. Therefore, early diagnosis and medical treatment of sepsis in critically ill…
Sepsis, a critical condition from the body's response to infection, poses a major global health crisis affecting all age groups. Timely detection and intervention are crucial for reducing healthcare expenses and improving patient outcomes.…
We present a scalable end-to-end classifier that uses streaming physiological and medication data to accurately predict the onset of sepsis, a life-threatening complication from infections that has high mortality and morbidity. Our proposed…
Sepsis is a life threatening condition that requires timely detection in intensive care settings. Traditional machine learning approaches, including Naive Bayes, Support Vector Machine (SVM), Random Forest, and XGBoost, often rely on manual…
Sepsis is a severe condition responsible for many deaths in the United States and worldwide, making accurate prediction of outcomes crucial for timely and effective treatment. Previous studies employing machine learning faced limitations in…
The timeliness of detection of a sepsis event in progress is a crucial factor in the outcome for the patient. Machine learning models built from data in electronic health records can be used as an effective tool for improving this…
Sepsis is the leading cause of in-hospital mortality in the USA. Early sepsis onset prediction and diagnosis could significantly improve the survival of sepsis patients. Existing predictive models are usually trained on high-quality data…
Sepsis is a syndrome that develops in the body in response to the presence of an infection. Characterized by severe organ dysfunction, sepsis is one of the leading causes of mortality in Intensive Care Units (ICUs) worldwide. These…