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Early detection of Parkinson's disease (PD) is important which can enable early initiation of therapeutic interventions and management strategies. However, methods for early detection still remain an unmet clinical need in PD. In this…

应用统计 · 统计学 2018-10-04 R Prashanth , Sumantra Dutta Roy

Multiscale modelling presents a multifaceted perspective into understanding the mechanisms of the brain and how neurodegenerative disorders like Parkinson's disease (PD) manifest and evolve over time. In this study, we propose a novel…

神经元与认知 · 定量生物学 2025-09-18 Aaron Herrera , Hina Shaheen

While convolutional neural networks (CNNs) have been successfully applied to many challenging classification applications, they typically require large datasets for training. When the availability of labeled data is limited, data…

计算机视觉与模式识别 · 计算机科学 2017-11-10 Terry Taewoong Um , Franz Michael Josef Pfister , Daniel Pichler , Satoshi Endo , Muriel Lang , Sandra Hirche , Urban Fietzek , Dana Kulić

The reliable segmentation of retinal vasculature can provide the means to diagnose and monitor the progression of a variety of diseases affecting the blood vessel network, including diabetes and hypertension. We leverage the power of…

图像与视频处理 · 电气工程与系统科学 2019-07-23 Ali Hatamizadeh , Hamid Hosseini , Zhengyuan Liu , Steven D. Schwartz , Demetri Terzopoulos

Atypical Parkinsonian Disorders (APD), also known as Parkinson-plus syndrome, are a group of neurodegenerative diseases that include progressive supranuclear palsy (PSP) and multiple system atrophy (MSA). In the early stages, overlapping…

计算机视觉与模式识别 · 计算机科学 2026-04-16 Mengyu Li , Ingibjörg Kristjánsdóttir , Thilo van Eimeren , Kathrin Giehl , Lotta M. Ellingsen , the ASAP Neuroimaging Initiative

Imaging-based early diagnosis of Alzheimer Disease (AD) has become an effective approach, especially by using nuclear medicine imaging techniques such as Positron Emission Topography (PET). In various literature it has been found that PET…

机器学习 · 计算机科学 2021-03-24 Jiaming Guo , Wei Qiu , Xiang Li , Xuandong Zhao , Ning Guo , Quanzheng Li

Parkinson's disease is a progressive and slowly developing neurodegenerative disease, characterized by dopaminergic neuron loss in the substantia nigra region of the brain. Despite extensive research by scientists, there is not yet a cure…

定量方法 · 定量生物学 2024-08-31 Pratham Kankariya , Rachita Rode , Kevin Mudaliar , Pranali Hatode

Alzheimer's Disease (AD) is a progressive neurodegenerative disease. Amnestic mild cognitive impairment (MCI) is a common first symptom before the conversion to clinical impairment where the individual becomes unable to perform activities…

计算机视觉与模式识别 · 计算机科学 2017-10-16 Donghuan Lu , Karteek Popuri , Weiguang Ding , Rakesh Balachandar , Mirza Faisal Beg

In the field of medical imaging, the advent of deep learning, especially the application of convolutional neural networks (CNNs) has revolutionized the analysis and interpretation of medical images. Nevertheless, deep learning methods…

计算机视觉与模式识别 · 计算机科学 2025-04-28 Xin Li , Wenhui Zhu , Peijie Qiu , Oana M. Dumitrascu , Amal Youssef , Yalin Wang

Alzheimer's disease is a progressive neurodegenerative disorder that primarily affects cognitive functions such as memory, thinking, and behavior. In this disease, there is a critical phase, mild cognitive impairment, that is really…

信号处理 · 电气工程与系统科学 2024-04-02 Arezoo Borji , Taha-Hossein Hejazi , Abbas Seifi

In recent days, Convolutional Neural Networks (CNN) have demonstrated impressive performance in medical image analysis. However, there is a lack of clear understanding of why and how the Convolutional Neural Network performs so well for…

图像与视频处理 · 电气工程与系统科学 2019-12-30 Jyoti Islam , Yanqing Zhang

3D image scans are an assessment tool for neurological damage in Parkinson's disease (PD) patients. This diagnosis process can be automatized to help medical staff through Decision Support Systems (DSSs), and Convolutional Neural Networks…

We present InceptoFormer, a multi-signal neural framework designed for Parkinson's Disease (PD) severity evaluation via gait dynamics analysis. Our architecture introduces a 1D adaptation of the Inception model, which we refer to as…

计算机视觉与模式识别 · 计算机科学 2025-08-07 Safwen Naimi , Arij Said , Wassim Bouachir , Guillaume-Alexandre Bilodeau

Diabetic retinopathy is one of the most threatening complications of diabetes that leads to permanent blindness if left untreated. One of the essential challenges is early detection, which is very important for treatment success.…

机器学习 · 计算机科学 2020-03-06 Borys Tymchenko , Philip Marchenko , Dmitry Spodarets

Parkinson's disease (PD) is a highly heterogeneous disease, including which motor symptoms are dominating. Imaging biomarkers that support subtype stratification could also improve biological understanding and study design, and enable…

Parkinson's disease (PD), a neurodegenerative disorder, often manifests as speech and voice dysfunction. While utilizing voice data for PD detection has great potential in clinical applications, the widely used deep learning models…

机器学习 · 计算机科学 2023-09-26 Yicheng Wang , Xiaotian Han , Leisheng Yu , Na Zou

Early diagnosis of melanoma, which can save thousands of lives, relies heavily on the analysis of dermoscopic images. One crucial diagnostic criterion is the identification of unusual pigment network (PN). However, distinguishing between…

图像与视频处理 · 电气工程与系统科学 2026-01-21 M. A. Rasel , Sameem Abdul Kareem , Unaizah Obaidellah

Convolutional neural networks (CNNs) show impressive performance for image classification and detection, extending heavily to the medical image domain. Nevertheless, medical experts are sceptical in these predictions as the nonlinear…

计算机视觉与模式识别 · 计算机科学 2017-06-30 Waleed M. Gondal , Jan M. Köhler , René Grzeszick , Gernot A. Fink , Michael Hirsch

Early and accurate classification of retinal diseases is critical to counter vision loss and for guiding clinical management of retinal diseases. In this study, we proposed a deep learning method for retinal disease classification utilizing…

计算机视觉与模式识别 · 计算机科学 2026-02-24 Mohammad Tahmid Noor , Shayan Abrar , Jannatul Adan Mahi , Md Parvez Mia , Asaduzzaman Hridoy , Samanta Ghosh

Gait analysis, an expanding research area, employs non invasive sensors and machine learning techniques for a range of applicatio ns. In this study, we concentrate on gait analysis for detecting cognitive decline in Parkinson's disease (PD)…

信号处理 · 电气工程与系统科学 2023-06-13 Abdullah Alharthi