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We report new statistical time-series analysis tools providing significant improvements in the rapid, precision extraction of discrete state dynamics from large databases of experimental observations of molecular machines. By building…

Developmental constraints have been postulated to limit the space of feasible phenotypes and thus shape animal evolution. These constraints have been suggested to be the strongest during either early or mid-embryogenesis, which corresponds…

种群与进化 · 定量生物学 2013-03-14 Barbara Piasecka , Pawel Lichocki , Sebastien Moretti , Sven Bergmann , Marc Robinson-Rechavi

In vivo measurement of the mechanical properties of thin-walled soft tissues (e.g., mitral valve, artery and bladder) and in situ mechanical characterization of thin-walled artificial soft biomaterials in service are of great challenge and…

软凝聚态物质 · 物理学 2020-09-02 Guo-Yang Li , Qiong He , Robert Mangan , Guoqiang Xu , Chi Mo , Jianwen Luo , Michel Destrade , Yanping Cao

State estimation in multi-layer turbulent flow fields with only a single layer of partial observation remains a challenging yet practically important task. Applications include inferring the state of the deep ocean by exploiting surface…

流体动力学 · 物理学 2025-09-30 Zhongrui Wang , Nan Chen , Di Qi

Liquid mixtures can separate into phases with distinct composition. This phenomenon has recently come back to prominence due to its role in complex biological liquids, such as the cytoplasm, which contain thousands of components. For simple…

统计力学 · 物理学 2025-12-11 Rodrigo Braz Teixeira , Izaak Neri , Pablo Sartori

In active systems, whose constituents have non-equilibrium dynamics at local level, fluid-fluid phase separation is widely observed. Examples include the formation of membraneless organelles within cells; the clustering of self-propelled…

软凝聚态物质 · 物理学 2025-07-11 M. E. Cates , C. Nardini

We present a computational live bacteria detection system that periodically captures coherent microscopy images of bacterial growth inside a 60 mm diameter agar-plate and analyzes these time-lapsed holograms using deep neural networks for…

The combination of microwave and microfluidic technologies has the potential to enable wireless monitoring and interaction with bioparticles, facilitating in this way the exploration of a still largely uncharted territory at the…

系统与控制 · 电气工程与系统科学 2022-09-21 Cesar Palacios , Marc Jofre , Lluis Jofre , Jordi Romeu , Luis Jofre-Roca

Task-oriented grasping (TOG) is essential for robots to perform manipulation tasks, requiring grasps that are both stable and compliant with task-specific constraints. Humans naturally grasp objects in a task-oriented manner to facilitate…

机器人学 · 计算机科学 2025-03-04 Dehao Huang , Wenlong Dong , Chao Tang , Hong Zhang

We present eMAGPIE (extended Multilevel-Adaptive-Guided Ptychographic Iterative Engine), a stochastic multigrid method for blind ptychographic phase retrieval that jointly recovers the object and the probe. We recast the task as the…

数值分析 · 数学 2025-11-04 Borong Zhang , Junjing Deng , Yi Jiang , Zichao Wendy Di

Diffusion-based microfluidic gradient generators (DMGGs) are essential for various in-vitro studies due to their ability to provide a convection-free concentration gradient. However, these systems, often referred to as membrane-based DMGGs,…

流体动力学 · 物理学 2025-03-05 Vahid Khandan , Ryan C. Chiechi , Elisabeth Verpoorte , Klaus Mathwig

The detection of terrestrial planets by Darwin/TPF missions will require extremely high quality wavefronts. Single-mode fibers have proven to be powerful beam cleaning components in the near-infrared, but are currently not available in the…

天体物理学 · 物理学 2007-05-23 P. Borde , G. Perrin , A. Amy-Klein , C. Daussy , G. Maze

Antimicrobial susceptibility testing (AST) is a standard clinical procedure used to quantify antimicrobial resistance (AMR). Currently, the gold standard method requires incubation for 18-24 h and subsequent inspection for growth by a…

In this paper, we propose, analyze, and test a new fully discrete, efficient, decoupled, stable, and practically second-order time-stepping algorithm for computing MHD ensemble flow averages under uncertainties in the initial conditions and…

数值分析 · 数学 2021-01-19 Muhammad Mohebujjaman

The challenge to fully exploit the potential of existing and upcoming scientific instruments like large single-dish radio telescopes is to process the collected massive data effectively and efficiently. As a "quasi 2D stencil computation"…

分布式、并行与集群计算 · 计算机科学 2022-07-12 Hao Wang , Ce Yu , Jian Xiao , Shanjiang Tang , Min Long , Ming Zhu

(abridged) We present a detailed derivation of a simple hydrodynamic two-fluid model, which aims at the description of the phase separation of non-entangled polymer solutions, where viscoelastic effects play a role. It is directly based…

This paper studies the thermo-poroelasticity model. By introducing an intermediate variable, we transform the original three-field model into a four-field model. Building upon this four-field model, we present both a coupled finite element…

数值分析 · 数学 2025-07-23 Mingchao Cai , Jingzhi Li , Ziliang Li , Qiang Liu

Extraction of Electrocardiography (ECG or EKG) signals of mother and baby is a challenging task, because one single device is used and it receives a mixture of multiple heart beats. In this paper, we would like to design a filter to…

计算机视觉与模式识别 · 计算机科学 2014-11-07 Wei Wang

Contemporary robots in precision agriculture focus primarily on automated harvesting or remote sensing to monitor crop health. Comparatively less work has been performed with respect to collecting physical leaf samples in the field and…

机器人学 · 计算机科学 2022-08-11 Merrick Campbell , Amel Dechemi , Konstantinos Karydis

Electroencephalogram (EEG) signals are often corrupted with unintended artifacts which need to be removed for extracting meaningful clinical information from them. Typically a priori knowledge of the nature of the artifacts is needed for…

医学物理 · 物理学 2018-03-02 Valentina Bono , Saptarshi Das , Wasifa Jamal , Koushik Maharatna