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相关论文: Bounding Causes of Effects with Mediators

200 篇论文

Causal mediation analysis (CMA) is a powerful method to dissect the total effect of a treatment into direct and mediated effects within the potential outcome framework. This is important in many scientific applications to identify the…

机器学习 · 计算机科学 2023-06-14 Ziyang Jiang , Yiling Liu , Michael H. Klein , Ahmed Aloui , Yiman Ren , Keyu Li , Vahid Tarokh , David Carlson

The increase in the use of mobile and wearable devices now allows dense assessment of mediating processes over time. For example, a pharmacological intervention may have an effect on smoking cessation via reductions in momentary withdrawal…

统计方法学 · 统计学 2022-11-18 Donna L. Coffman , John J. Dziak , Kaylee Litson , Yajnaseni Chakraborti , Megan E. Piper , Runze Li

Principal stratification (PS) is a commonly used approach for understanding the mechanisms through which a treatment affects an outcome. The goal of this work is to extend the PS framework to studies with continuous treatments, which…

统计方法学 · 统计学 2025-05-20 Joseph Antonelli , Minxuan Wu , Fabrizia Mealli , Brenden Beck , Alessandra Mattei

Probabilities of causation provide explanatory information on the observed occurrence (causal necessity) and non-occurrence (causal sufficiency) of events. Here, we adapt these probabilities (probability of necessity, probability of…

定量方法 · 定量生物学 2025-04-28 Bronner P. Gonçalves

Causal effect estimation has been studied by many researchers when only observational data is available. Sound and complete algorithms have been developed for pointwise estimation of identifiable causal queries. For non-identifiable causal…

机器学习 · 统计学 2023-06-26 Ziwei Jiang , Lai Wei , Murat Kocaoglu

The problem of individualization is recognized as crucial in almost every field. Identifying causes of effects in specific events is likewise essential for accurate decision making. However, such estimates invoke counterfactual…

统计方法学 · 统计学 2021-05-04 Scott Mueller , Ang Li , Judea Pearl

Mediation analysis is difficult when the number of potential mediators is larger than the sample size. In this paper we propose new inference procedures for the indirect effect in the presence of high-dimensional mediators for linear…

统计方法学 · 统计学 2019-10-29 Ruixuan Rachel Zhou , Liewei Wang , Sihai Dave Zhao

In settings where interference is present, direct effects are commonly defined as the average effect of a unit's treatment on their own outcome while fixing the treatment status or probability among interfering units, and spillover effects…

统计方法学 · 统计学 2025-06-10 Fei Fang , Edoardo M Airoldi , Laura Forastiere

Researchers are often interested in learning not only the effect of treatments on outcomes, but also the pathways through which these effects operate. A mediator is a variable that is affected by treatment and subsequently affects outcome.…

统计方法学 · 统计学 2021-12-22 Jeremiah Jones , Ashkan Ertefaie , Robert L. Strawderman

Factorial experiments are ubiquitous in the social and biomedical sciences, but when units fail to comply with each assigned factors, identification and estimation of the average treatment effects become impossible without strong…

统计方法学 · 统计学 2025-08-06 Matthew Blackwell , Nicole E. Pashley

Many epidemiological questions concern potential interventions to alter the pathways presumed to mediate an association. For example, we consider a study that investigates the benefit of interventions in young adulthood for ameliorating the…

统计方法学 · 统计学 2020-07-14 Margarita Moreno-Betancur , Paul Moran , Denise Becker , George C Patton , John B Carlin

Suppose that we are interested in the average causal effect of a binary treatment on an outcome when this relationship is confounded by a binary confounder. Suppose that the confounder is unobserved but a nondifferential proxy of it is…

统计方法学 · 统计学 2020-08-25 Jose M. Peña

In response to the unique challenge created by high-dimensional mediators in mediation analysis, this paper presents a novel procedure for testing the nullity of the mediation effect in the presence of high-dimensional mediators. The…

统计方法学 · 统计学 2025-05-28 Yinan Lin , Zijian Guo , Baoluo Sun , Zhenhua Lin

Using observed language to understand interpersonal interactions is important in high-stakes decision making. We propose a causal research design for observational (non-experimental) data to estimate the natural direct and indirect effects…

计算与语言 · 计算机科学 2021-09-17 Katherine A. Keith , Douglas Rice , Brendan O'Connor

Causal analysis may be affected by selection bias, which is defined as the systematic exclusion of data from a certain subpopulation. Previous work in this area focused on the derivation of identifiability conditions. We propose instead a…

机器学习 · 统计学 2022-08-03 Marco Zaffalon , Alessandro Antonucci , Rafael Cabañas , David Huber , Dario Azzimonti

In most medical research, the average treatment effect is used to evaluate a treatment's performance. However, precision medicine requires knowledge of individual treatment effects: What is the difference between a unit's measurement under…

统计计算 · 统计学 2022-08-30 Mingyang Cai , Stef van Buuren , Gerko Vink

Observational studies are often used to understand relationships between exposures and outcomes. They do not, however, allow conclusions about causal relationships to be drawn unless statistical techniques are used to account for the…

统计方法学 · 统计学 2021-07-20 Andreas Markoulidakis , Peter Holmans , Philip Pallmann , Monica Busse , Beth Ann Griffin

Causal effect estimation is important for many tasks in the natural and social sciences. We design algorithms for the continuous partial identification problem: bounding the effects of multivariate, continuous treatments when unmeasured…

机器学习 · 统计学 2023-05-18 Kirtan Padh , Jakob Zeitler , David Watson , Matt Kusner , Ricardo Silva , Niki Kilbertus

We examine the problem of causal response estimation for complex objects (e.g., text, images, genomics). In this setting, classical \emph{atomic} interventions are often not available (e.g., changes to characters, pixels, DNA base-pairs).…

机器学习 · 计算机科学 2021-06-11 Limor Gultchin , David S. Watson , Matt J. Kusner , Ricardo Silva

An informed sender communicates with an uninformed receiver through a sequence of uninformed mediators; agents' utilities depend on receiver's action and the state. For any number of mediators, the sender's optimal value is characterized.…

理论经济学 · 经济学 2022-09-13 Itai Arieli , Yakov Babichenko , Fedor Sandomirskiy