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Variance reduction for causal inference in the presence of network interference is often achieved through either outcome modeling, typically analyzed under unit-randomized Bernoulli designs, or clustered experimental designs, typically…

统计方法学 · 统计学 2026-01-19 Matthew Eichhorn , Samir Khan , Johan Ugander , Christina Lee Yu

Consider a situation with two treatments, the first of which is randomized but the second is not, and the multifactor version of this. Interest is in treatment effects, defined using standard factorial notation. We define estimators for the…

统计方法学 · 统计学 2022-02-09 Nicole E. Pashley , Kristen B. Hunter , Katy McKeough , Donald B. Rubin , Tirthankar Dasgupta

e consider the experimental design problem in an online environment, an important practical task for reducing the variance of estimates in randomized experiments which allows for greater precision, and in turn, improved decision making. In…

统计方法学 · 统计学 2022-03-07 David Arbour , Drew Dimmery , Tung Mai , Anup Rao

Observational studies are valuable tools for inferring causal effects in the absence of controlled experiments. However, these studies may be biased due to the presence of some relevant, unmeasured set of covariates. One approach to…

统计方法学 · 统计学 2026-02-17 William Bekerman , Abhinandan Dalal , Carlo del Ninno , Dylan S. Small

An important step for any causal inference study design is understanding the distribution of the treated and control subjects in terms of measured baseline covariates. However, not all baseline variation is equally important. In the…

统计方法学 · 统计学 2021-07-02 Rachael C. Aikens , Michael Baiocchi

Generalized causal effect estimands, including the Mann-Whitney parameter and causal net benefit, provide flexible summaries of treatment effects in randomized experiments with non-Gaussian or multivariate outcomes. We develop a unified…

统计方法学 · 统计学 2026-02-27 Xinyuan Chen , Fan Li

In this paper, we discuss causal inference on the efficacy of a treatment or medication on a time-to-event outcome with competing risks. Although the treatment group can be randomized, there can be confoundings between the compliance and…

统计方法学 · 统计学 2016-12-06 Cheng Zheng , Ran Dai , Parameswaran Hari , Mei-Jie Zhang

How should researchers analyze randomized experiments in which the main outcome is latent and measured in multiple ways but each measure contains some degree of error? We first identify a critical study-specific noncomparability problem in…

计量经济学 · 经济学 2026-01-13 Jiawei Fu , Donald P. Green

Randomized experiments in which the treatment of a unit can affect the outcomes of other units are becoming increasingly common in healthcare, economics, and in the social and information sciences. From a causal inference perspective, the…

统计方法学 · 统计学 2017-02-14 Daniel L. Sussman , Edoardo M. Airoldi

Researchers often turn to block randomization to increase the precision of their inference or due to practical considerations, such as in multisite trials. However, if the number of treatments under consideration is large it might not be…

统计方法学 · 统计学 2025-08-26 Taehyeon Koo , Nicole E. Pashley

A fundamental issue in causal inference for Big Observational Data is confounding due to covariate imbalances between treatment groups. This can be addressed by designing the data prior to analysis. Existing design methods, developed for…

统计方法学 · 统计学 2022-03-17 Yumin Zhang , Arman Sabbaghi

This paper considers the estimation of treatment effects in randomized experiments with complex experimental designs, including cases with interference between units. We develop a design-based estimation theory for arbitrary experimental…

计量经济学 · 经济学 2025-05-27 Haoge Chang

We consider a potential outcomes model in which interference may be present between any two units but the extent of interference diminishes with spatial distance. The causal estimand is the global average treatment effect, which compares…

统计方法学 · 统计学 2022-09-16 Michael P. Leung

We present an optimized rerandomization design procedure for a non-sequential treatment-control experiment. Randomized experiments are the gold standard for finding causal effects in nature. But sometimes random assignments result in…

统计方法学 · 统计学 2021-01-26 Adam Kapelner , Abba M. Krieger , Michael Sklar , David Azriel

This paper provides a design-based framework for variance (bound) estimation in experimental analysis. Results are applicable to virtually any combination of experimental design, linear estimator (e.g., difference-in-means, OLS, WLS) and…

统计方法学 · 统计学 2021-09-21 Joel A. Middleton

Randomized experiments on a network often involve interference between connected units; i.e., a situation in which an individual's treatment can affect the response of another individual. Current approaches to deal with interference, in…

统计方法学 · 统计学 2017-05-17 Guillaume Basse , Edoardo Airoldi

Causal inference with observational studies often suffers from unmeasured confounding, yielding biased estimators based on the unconfoundedness assumption. Sensitivity analysis assesses how the causal conclusions change with respect to…

统计方法学 · 统计学 2024-04-01 Sizhu Lu , Peng Ding

This paper extends the design-based framework to settings with multi-way cluster dependence, and shows how multi-way clustering can be justified when clustered assignment and clustered sampling occurs on different dimensions, or when either…

计量经济学 · 经济学 2023-09-06 Luther Yap

Causal inference, as a major research area in statistics and data science, plays a central role across diverse fields such as medicine, economics, education, and the social sciences. Design-based causal inference begins with randomized…

统计方法学 · 统计学 2025-12-01 Xin Lu , Wanjia Fu , Hongzi Li , Haoyang Yu , Honghao Zhang , Ke Zhu , Hanzhong Liu

Many scientific questions in biomedical, environmental, and psychological research involve understanding the effects of multiple factors on outcomes. While factorial experiments are ideal for this purpose, randomized controlled treatment…

统计方法学 · 统计学 2025-12-03 Ruoqi Yu , Peng Ding