相关论文: Heterogeneous Angular Spectrum Approach for Trans-…
During the first years of life, the human brain undergoes dynamic spatially-heterogeneous changes, involving differentiation of neuronal types, dendritic arborization, axonal ingrowth, outgrowth and retraction, synaptogenesis, and…
Acoustic impedance mismatches between soft tissues and bones are known to result in strong aberrations in optoacoustic and ultrasound images. Of particular importance are the severe distortions introduced by the human skull, impeding…
Transcranial ultrasound applications require accurate simulations to predict intracranial acoustic pressure fields. The current gold standard typically consists of calculating a longitudinal ultrasound wave propagation using a fluid skull…
Ultrasound brain imaging remains challenging due to the large difference in sound speed between the skull and brain tissues and the difficulty of coupling large probes to the skull. This work aims to achieve quantitative transcranial…
Acoustic holography in the megahertz frequency range can impact numerous applications, including manufacturing, non-destructive testing, and transcranial ultrasound. However, designing lens topologies for complex acoustic holograms in the…
Transcranial focused ultrasound (FUS) is a non-invasive technique for therapy and study of brain neural activation. Here we report on the design and characterization of a new MR-guided FUS transducer for neuromodulation in non-human…
The goal of unsupervised anomaly segmentation (UAS) is to detect the pixel-level anomalies unseen during training. It is a promising field in the medical imaging community, e.g, we can use the model trained with only healthy data to segment…
Objective. While ultrasound is largely established for use in diagnostic imaging and heating therapies, its application for neuromodulation is relatively new and not well understood. The objective of the present study was to investigate…
Compared to single-source imaging systems, dual-source imaging systems equipped with two cross-distributed scanning beams significantly enhance temporal resolution and capture more comprehensive object scanning information. Nevertheless,…
Hyperspectral imaging (HSI) holds great potential for healthcare due to its rich spectral information. However, acquiring HSI data remains costly and technically demanding. Hyperspectral image reconstruction offers a practical solution by…
Transcranial focused ultrasound stimulation (TUS) holds promise for non-invasive neural modulation in treating neurological disorders. Most clinically relevant targets are deep within the brain (near or at its geometric center), surrounded…
High-resolution optical microscopy has transformed biological imaging, yet its resolution and contrast deteriorate with depth due to multiple light scattering. Conventional correction strategies typically approximate the medium as one or a…
Transcranial ultrasound simulations are increasingly used to predict in situ exposure parameters for ultrasound therapies in the brain. However, there can be considerable uncertainty in estimating the acoustic medium properties of the skull…
Identifying what aspects of brain activity are responsible for conscious perception remains one of the most challenging problems in science. While progress has been made through psychophysical studies employing EEG and fMRI, research would…
The prevalence of Autism Spectrum Disorder (ASD) has surged rapidly over the past decade, posing significant challenges in communication, behavior, and focus for affected individuals. Current diagnostic techniques, though effective, are…
The purpose of this work is to demonstrate a robust and clinically validated method for correcting sound speed aberrations in medical ultrasound. We propose a correction method that calculates focusing delays directly from the observed…
Transient brain-wide neuroimaging on a microscopic scale is pivotal for brain research, yet current modalities face challenges in meeting such spatiotemporal requirements. Functional ultrasound (fUS) enables transient neurovascular imaging…
Currently, every 1 in 54 children have been diagnosed with Autism Spectrum Disorder (ASD), which is 178% higher than it was in 2000. An early diagnosis and treatment can significantly increase the chances of going off the spectrum and…
Ultrasound imaging systems rely on accurate point spread function (PSF) estimation to support advanced image quality enhancement techniques such as deconvolution and speckle reduction. Phase aberration, caused by sound speed inhomogeneity…
The standard technique used by commercial medical ultrasound systems to form B-mode images is delay and sum (DAS) beamforming. However, DAS often results in limited image resolution and contrast, which are governed by the center frequency…