相关论文: Heterogeneous Angular Spectrum Approach for Trans-…
High resolution transcranial ultrasound imaging in humans has been a persistent challenge for ultrasound due to the imaging degradation effects from aberration and reverberation. These mechanisms depend strongly on skull morphology and they…
Imaging the human brain vasculature with high spatial and temporal resolution remains challenging in the clinic today. Transcranial ultrasound is scarcely used for cerebrovascular imaging, due to low sensitivity and strong phase aberrations…
Transcranial ultrasound therapy uses focused acoustic energy to induce therapeutic bioeffects in the brain. Ultrasound must be transmitted through the skull, which is highly attenuating and heterogeneous, causing beam distortion, reducing…
The angular spectrum approach (ASA)---a fast, frequency domain method for calculation of the acoustic field---enables passive source localization and modeling forward propagation in homogeneous media with high computational efficiency. Here…
Acoustic holographic lenses, also known as acoustic holograms, can change the phase of a transmitted wavefront in order to shape and construct complex ultrasound pressure fields, often for focusing the acoustic energy on a target region.…
Transcranial focused ultrasound (tFUS) offers noninvasive access to deep brain circuits but remains limited by skull-induced phase aberration, acoustic impedance mismatch, and poor volumetric control of intracranial pressure fields.…
Skull-induced aberrations remain a major drawback of transcranial ultrasound localization microscopy (ULM), degrading sensitivity and spatial accuracy through microbubble mislocalization, false detections, and imaging artifacts, such as…
Traumatic brain injury studies on the living human brain are experimentally infeasible. We present a simulation approach that models ultrasound propagation in the human brain while it is moving due to the complex shear shock wave…
Ultrasound vortices have rapidly expanded their applications to areas like particle trapping, contactless manipulation, acoustic communications. In ultrasonic imaging and therapy involving bone tissues, these vortex beams offer intriguing…
Transcranial ultrasound (TUS) has emerged as a promising tool in clinical and research settings due to its potential to modulate neuronal activity, open the blood-brain barrier, facilitate targeted drug delivery via nanoparticles, and…
We report 3D-printed acoustic holographic lenses for the formation of ultrasonic fields of complex spatial distribution inside the skull. Using holographic lenses, we experimentally, numerically and theoretically produce acoustic beams…
The correction of the aberration of transcranial focused ultrasounds is a relevant issue for enhancing various non-invasive medical treatments. Emission through multi-element phased arrays has been the most widely accepted method to reduce…
In ultrasound imaging, propagation of an acoustic wavefront through heterogeneous media causes phase aberrations that degrade the coherence of the reflected wavefront, leading to reduced image resolution and contrast. Adaptive imaging…
Transcranial ultrasound imaging is currently limited by attenuation and aberration induced by the skull. First used in contrast-enhanced ultrasound (CEUS), highly echoic microbubbles allowed for the development of novel imaging modalities…
Transcranial focused ultrasound (tFUS) is an emerging modality for non-invasive brain stimulation and therapeutic intervention, offering millimeter-scale spatial precision and the ability to target deep brain structures. However, the…
A plethora of machine learning methods have been applied to imaging data, enabling the construction of clinically relevant imaging signatures of neurological and neuropsychiatric diseases. Oftentimes, such methods don't explicitly model the…
Transcranial ultrasound is more and more used for therapy and imaging of the brain. However, the skull is a highly attenuating and aberrating medium, with different structures and acoustic properties between samples and even within a…
Increasing the volume of training data can enable the auxiliary diagnostic algorithms for Autism Spectrum Disorder (ASD) to learn more accurate and stable models. However, due to the significant heterogeneity and domain shift in rs-fMRI…
Focusing waves inside inhomogeneous media is a fundamental problem for imaging. Spatial variations of wave velocity can strongly distort propagating wavefronts and degrade image quality. Adaptive focusing can compensate for such aberration,…
Conventional ultrasound (US) imaging employs the delay and sum (DAS) receive beamforming with dynamic receive focus for image reconstruction due to its simplicity and robustness. However, the DAS beamforming follows a geometrical method of…