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Degeneration and adaptation are two competing sides of the same coin called resilience in the progressive processes of brain aging or diseases. Degeneration accumulates during brain aging and other cerebral activities, causing structural…

We study the question of how concepts that have structure get represented in the brain. Specifically, we introduce a model for hierarchically structured concepts and we show how a biologically plausible neural network can recognize these…

人工智能 · 计算机科学 2024-02-28 Nancy Lynch , Frederik Mallmann-Trenn

Biological neural networks define the brain function and intelligence of humans and other mammals, and form ultra-large, spatial, structured graphs. Their neuronal organization is closely interconnected with the spatial organization of the…

A fundamental question in neuroscience is how structure and function of neural systems are related. We study this interplay by combining a familiar auto-associative neural network with an evolving mechanism for the birth and death of…

适应与自组织系统 · 物理学 2019-04-26 Ana P. Millán , J. J. Torres , S. Johnson , J. Marro

The relation between large-scale brain structure and function is an outstanding open problem in neuroscience. We approach this problem by studying the dynamical regime under which realistic spatio-temporal patterns of brain activity emerge…

神经元与认知 · 定量生物学 2014-05-27 Ariel Haimovici , Enzo Tagliazucchi , Pablo Balenzuela , Dante R. Chialvo

Memory information in the brain is commonly believed to be stored in the synapse. However, a recent groundbreaking electrophysiology research has raised the possibility that memory information may actually be stored inside the neuron…

神经元与认知 · 定量生物学 2021-01-26 James Tee , Desmond P. Taylor

Neural electrical activity is fundamental to brain function, underlying a range of cognitive and behavioral processes, including movement, perception, decision-making, and consciousness. Abnormal patterns of neural signaling often indicate…

神经元与认知 · 定量生物学 2025-09-03 Zhizhang Yuan , Fanqi Shen , Meng Li , Yuguo Yu , Chenhao Tan , Yang Yang

This chapter sheds light on the synaptic organization of the brain from the perspective of computational neuroscience. It provides an introductory overview on how to account for empirical data in mathematical models, implement such models…

Evolution and its intelligence element present thrill and challenges in its exploration. Yet, how species have memory, retrieve them and maintain continuity are the fundamental questions. Most of the phenomenon can only be hypothesised by…

神经元与认知 · 定量生物学 2024-07-09 Anil Kumar Sharma , Asha Sharma

Cognitive function is driven by dynamic interactions between large-scale neural circuits or networks, enabling behavior. Fundamental principles constraining these dynamic network processes have remained elusive. Here we use network control…

神经元与认知 · 定量生物学 2015-10-28 Shi Gu , Fabio Pasqualetti , Matthew Cieslak , Scott T. Grafton , Danielle S. Bassett

Redundancy is a ubiquitous property of the nervous system. This means that vastly different configurations of cellular and synaptic components can enable the same neural circuit functions. However, until recently very little brain disorder…

神经元与认知 · 定量生物学 2021-02-08 Beatriz E. P. Mizusaki , Cian O'Donnell

Understanding how the brain learns to compute functions reliably, efficiently and robustly with noisy spiking activity is a fundamental challenge in neuroscience. Most sensory and motor tasks can be described as dynamical systems and could…

神经元与认知 · 定量生物学 2017-05-24 Sophie Denève , Alireza Alemi , Ralph Bourdoukan

It has been proposed that there is a wave excitation in animal brains, whose role is to represent three dimensional local space in a working memory. Evidence for the wave comes from the mammalian thalamus, the central body of the insect…

神经元与认知 · 定量生物学 2024-08-12 Robert Worden

This is the first in a series of connected papers discussing the problem of a dynamically reconfigurable universal learning neurocomputer that could serve as a computational model for the whole human brain. The whole series is entitled "The…

人工智能 · 计算机科学 2007-05-23 Victor Eliashberg

How intelligence arises from the brain is a central problem in science. A crucial aspect of intelligence is dealing with uncertainty -- developing good predictions about one's environment, and converting these predictions into decisions.…

神经元与认知 · 定量生物学 2024-06-13 Max Dabagia , Daniel Mitropolsky , Christos H. Papadimitriou , Santosh S. Vempala

Neuroscientists often describe neural activity as a representation of something, or claim to have found evidence for a neural representation. But what do these statements mean? The reasons to call some neural activity a representation and…

神经元与认知 · 定量生物学 2021-04-29 Ben Baker , Benjamin Lansdell , Konrad Kording

The human body is a complex organism whose gross mechanical properties are enabled by an interconnected musculoskeletal network controlled by the nervous system. The nature of musculoskeletal interconnection facilitates stability, voluntary…

The human brain is ultimately responsible for all thoughts and movements that the body produces. This allows humans to successfully interact with their environment. If the brain is not functioning properly many abilities of human can be…

神经元与认知 · 定量生物学 2018-07-09 Esmaeil Seraj

The brain as an astonishingly remarkable device has been studied from various angles. It is now well known that neurons are the seat of all activities of the brain function. The dynamical properties pertaining to a single neuron and a…

神经元与认知 · 定量生物学 2007-05-23 I. Mitra

It is still not fully understood exactly how neural networks are able to solve the complex tasks that have recently pushed AI research forward. We present a novel method for determining how information is structured inside a neural network.…

神经与进化计算 · 计算机科学 2019-02-04 Peter E. Lillian , Richard Meyes , Tobias Meisen