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Despite decades of clinical research, sepsis remains a global public health crisis with high mortality, and morbidity. Currently, when sepsis is detected and the underlying pathogen is identified, organ damage may have already progressed to…

Sepsis is a life-threatening host response to infection associated with high mortality, morbidity, and health costs. Its management is highly time-sensitive since each hour of delayed treatment increases mortality due to irreversible organ…

机器学习 · 计算机科学 2020-10-16 Michael Moor , Max Horn , Bastian Rieck , Damian Roqueiro , Karsten Borgwardt

Sepsis, characterized by a dysregulated immune response to infection, results in significant mortality, morbidity, and healthcare costs. The timely prediction of sepsis progression is crucial for reducing adverse outcomes through early…

机器学习 · 计算机科学 2026-01-01 Alireza Rafiei , Farshid Hajati , Alireza Rezaee , Amirhossien Panahi , Shahadat Uddin

Sepsis is a life-threatening organ malfunction caused by the host's inability to fight infection, which can lead to death without proper and immediate treatment. Therefore, early diagnosis and medical treatment of sepsis in critically ill…

机器学习 · 计算机科学 2023-04-14 Kevin Ewig , Xiangwen Lin , Tucker Stewart , Katherine Stern , Grant O'Keefe , Ankur Teredesai , Juhua Hu

Sepsis is a life-threatening condition that requires rapid detection and treatment to prevent progression to severe sepsis, septic shock, or multi-organ failure. Despite advances in medical technology, it remains a major challenge for…

机器学习 · 计算机科学 2025-11-11 Atharva Thakur , Shruti Dhumal

Current machine learning models aiming to predict sepsis from Electronic Health Records (EHR) do not account for the heterogeneity of the condition, despite its emerging importance in prognosis and treatment. This work demonstrates the…

定量方法 · 定量生物学 2020-11-24 Zina Ibrahim , Honghan Wu , Ahmed Hamoud , Lukas Stappen , Richard Dobson , Andrea Agarossi

This study proposes the use of Machine Learning models to predict the early onset of sepsis using deidentified clinical data from Montefiore Medical Center in Bronx, NY, USA. A supervised learning approach was adopted, wherein an XGBoost…

Sepsis, a critical condition from the body's response to infection, poses a major global health crisis affecting all age groups. Timely detection and intervention are crucial for reducing healthcare expenses and improving patient outcomes.…

机器学习 · 计算机科学 2024-07-12 MohammadAmin Ansari Khoushabar , Parviz Ghafariasl

Employing a machine learning approach we predict, up to 24 hours prior, a diagnosis of severe sepsis. Strongly predictive models are possible that use only text reports from the Electronic Health Record (EHR), and omit structured numerical…

计算机与社会 · 计算机科学 2017-12-01 Phil Culliton , Michael Levinson , Alice Ehresman , Joshua Wherry , Jay S. Steingrub , Stephen I. Gallant

Machine learning has been widely used in healthcare applications to approximate complex models, for clinical diagnosis, prognosis, and treatment. As deep learning has the outstanding ability to extract information from time series, its true…

机器学习 · 计算机科学 2022-11-14 Ke Liao , Wei Wang , Armagan Elibol , Lingzhong Meng , Xu Zhao , Nak Young Chong

Sepsis is the leading cause of death in non-coronary intensive care units. Moreover, a delay of antibiotic treatment of patients with severe sepsis by only few hours is associated with increased mortality. This insight makes accurate models…

We study multiple rule-based and machine learning (ML) models for sepsis detection. We report the first neural network detection and prediction results on three categories of sepsis. We have used the retrospective Medical Information Mart…

机器学习 · 计算机科学 2019-03-07 Avijit Mitra , Khalid Ashraf

We design and implement a temporal convolutional network model to predict sepsis onset. Our model is trained on data extracted from MIMIC III database, based on a retrospective analysis of patients admitted to intensive care unit who did…

机器学习 · 计算机科学 2022-06-01 Xing Wang , Yuntian He

Sepsis is a life-threatening condition with organ dysfunction and is a leading cause of death and critical illness worldwide. Even a few hours of delay in the treatment of sepsis results in increased mortality. Early detection of sepsis…

Sepsis is a major public health concern due to its high morbidity, mortality, and cost. Its clinical outcome can be substantially improved through early detection and timely intervention. By leveraging publicly available datasets, machine…

Sepsis is a syndrome that develops in the body in response to the presence of an infection. Characterized by severe organ dysfunction, sepsis is one of the leading causes of mortality in Intensive Care Units (ICUs) worldwide. These…

机器学习 · 计算机科学 2023-11-20 Tucker Stewart , Katherine Stern , Grant O'Keefe , Ankur Teredesai , Juhua Hu

Sepsis is a life threatening condition that requires timely detection in intensive care settings. Traditional machine learning approaches, including Naive Bayes, Support Vector Machine (SVM), Random Forest, and XGBoost, often rely on manual…

机器学习 · 计算机科学 2025-09-03 Hejiang Cai , Di Wu , Ji Xu , Xiang Liu , Yiziting Zhu , Xin Shu , Yujie Li , Bin Yi

Background: While machine learning (ML) models are rapidly emerging as promising screening tools in critical care medicine, the identification of homogeneous subphenotypes within populations with heterogeneous conditions such as pediatric…

Sepsis, a dysregulated immune system response to infection, is among the leading causes of morbidity, mortality, and cost overruns in the Intensive Care Unit (ICU). Early prediction of sepsis can improve situational awareness amongst…

机器学习 · 计算机科学 2019-08-14 Supreeth P. Shashikumar , Christopher Josef , Ashish Sharma , Shamim Nemati

Sepsis is a severe condition responsible for many deaths in the United States and worldwide, making accurate prediction of outcomes crucial for timely and effective treatment. Previous studies employing machine learning faced limitations in…

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