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相关论文: A Knowledge Graph-based Approach for Exploring the…

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Omics data analysis is crucial for studying complex diseases, but its high dimensionality and heterogeneity challenge classical statistical and machine learning methods. Graph neural networks have emerged as promising alternatives, yet the…

Increasing rates of opioid drug abuse and heightened prevalence of online support communities underscore the necessity of employing data mining techniques to better understand drug addiction using these rapidly developing online resources.…

社会与信息网络 · 计算机科学 2019-03-12 John Lu , Sumati Sridhar , Ritika Pandey , Mohammad Al Hasan , George Mohler

Thanks to the increasing availability of drug-drug interactions (DDI) datasets and large biomedical knowledge graphs (KGs), accurate detection of adverse DDI using machine learning models becomes possible. However, it remains largely an…

机器学习 · 计算机科学 2021-05-10 Yue Yu , Kexin Huang , Chao Zhang , Lucas M. Glass , Jimeng Sun , Cao Xiao

There have been more than 850,000 confirmed cases and over 48,000 deaths from the human coronavirus disease 2019 (COVID-19) pandemic, caused by novel severe acute respiratory syndrome coronavirus (SARS-CoV-2), in the United States alone.…

定量方法 · 定量生物学 2020-05-25 Xiangxiang Zeng , Xiang Song , Tengfei Ma , Xiaoqin Pan , Yadi Zhou , Yuan Hou , Zheng Zhang , George Karypis , Feixiong Cheng

Motivation: Drug repurposing is a viable solution for reducing the time and cost associated with drug development. However, thus far, the proposed drug repurposing approaches still need to meet expectations. Therefore, it is crucial to…

机器学习 · 计算机科学 2024-05-21 Ali Gharizadeh , Karim Abbasi , Amin Ghareyazi , Mohammad R. K. Mofrad , Hamid R. Rabiee

Background: Discovering potential drug-drug interactions (DDIs) is a long-standing challenge in clinical treatments and drug developments. Recently, deep learning techniques have been developed for DDI prediction. However, they generally…

机器学习 · 计算机科学 2024-03-20 Yaqing Wang , Zaifei Yang , Quanming Yao

Information extraction and data mining in biochemical literature is a daunting task that demands resource-intensive computation and appropriate means to scale knowledge ingestion. Being able to leverage this immense source of technical…

The exponential growth in scholarly publications necessitates advanced tools for efficient article retrieval, especially in interdisciplinary fields where diverse terminologies are used to describe similar research. Traditional…

Recent advances and achievements of artificial intelligence (AI) as well as deep and graph learning models have established their usefulness in biomedical applications, especially in drug-drug interactions (DDIs). DDIs refer to a change in…

Even for a conservative estimate, 80% of enterprise data reside in unstructured files, stored in data lakes that accommodate heterogeneous formats. Classical search engines can no longer meet information seeking needs, especially when the…

计算与语言 · 计算机科学 2024-06-06 Qiang Sun , Yuanyi Luo , Wenxiao Zhang , Sirui Li , Jichunyang Li , Kai Niu , Xiangrui Kong , Wei Liu

According to NSDUH (National Survey on Drug Use and Health), 20 million Americans consumed drugs in the past few 30 days. Combating illicit drug use is of great interest to public health and law enforcement agencies. Despite of the…

社会与信息网络 · 计算机科学 2016-11-28 Yiheng Zhou , Numair Sani , Jiebo Luo

The rising rate of drug-related deaths in the United States, largely driven by fentanyl, requires timely and accurate surveillance. However, critical overdose data are often buried in free-text coroner reports, leading to delays and…

Biomedical knowledge graphs (BKGs) have emerged as powerful tools for organizing and leveraging the vast and complex data found across the biomedical field. Yet, current reviews of BKGs often limit their scope to specific domains or…

计算与语言 · 计算机科学 2025-01-23 Yuxing Lu , Sin Yee Goi , Xukai Zhao , Jinzhuo Wang

Most existing knowledge graphs (KGs) in academic domains suffer from problems of insufficient multi-relational information, name ambiguity and improper data format for large-scale machine processing. In this paper, we present AceKG, a new…

信息检索 · 计算机科学 2018-08-08 Ruijie Wang , Yuchen Yan , Jialu Wang , Yuting Jia , Ye Zhang , Weinan Zhang , Xinbing Wang

The purpose of this work is to describe the Orkg-Leaderboard software designed to extract leaderboards defined as Task-Dataset-Metric tuples automatically from large collections of empirical research papers in Artificial Intelligence (AI).…

计算与语言 · 计算机科学 2023-05-19 Salomon Kabongo , Jennifer D'Souza , Sören Auer

Opioid related aberrant behaviors (ORABs) present novel risk factors for opioid overdose. This paper introduces a novel biomedical natural language processing benchmark dataset named ODD, for ORAB Detection Dataset. ODD is an…

Electronic Health Records (EHRs) and routine documentation practices play a vital role in patients' daily care, providing a holistic record of health, diagnoses, and treatment. However, complex and verbose EHR narratives overload healthcare…

Biomedical knowledge graphs (BioMedKGs) are essential infrastructures for biomedical and healthcare big data and artificial intelligence (AI), facilitating natural language processing, model development, and data exchange. For decades,…

Drug combination therapy is a well-established strategy for disease treatment with better effectiveness and less safety degradation. However, identifying novel drug combinations through wet-lab experiments is resource intensive due to the…

机器学习 · 计算机科学 2023-01-18 Zhihang Hu , Qinze Yu , Yucheng Guo , Taifeng Wang , Irwin King , Xin Gao , Le Song , Yu Li

Sharing and reusing research artifacts, such as datasets, publications, or methods is a fundamental part of scientific activity, where heterogeneity of resources and metadata and the common practice of capturing information in unstructured…

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