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The process of morphogenesis, which can be defined as an evolution of the form of an organism, is one of the most intriguing mysteries in the life sciences. It is clear, that gene expression patterns cannot explain the development of the…

其他定量生物学 · 定量生物学 2013-07-23 Nadya Morozova , Mikhail Shubin

We analyze a one dimensional version of a model of morphogen transport, a biological process governing cell differentiation. The model was proposed by Hufnagel et al. to describe the forming of morphogen gradient in the wing imaginal disc…

偏微分方程分析 · 数学 2014-12-17 Marcin Malogrosz

The broadcasting models on a d-ary tree T arise in many contexts such as biology, information theory, statistical physics and computer science. We consider the k-colouring model, i.e. the root of T is assigned an arbitrary colour and,…

离散数学 · 计算机科学 2013-11-08 Charilaos Efthymiou

Machine learning models can assist with metamaterials design by approximating computationally expensive simulators or solving inverse design problems. However, past work has usually relied on black box deep neural networks, whose reasoning…

机器学习 · 计算机科学 2022-10-04 Zhi Chen , Alexander Ogren , Chiara Daraio , L. Catherine Brinson , Cynthia Rudin

Color constancy is a fundamental ability of many biological visual systems and a crucial step in computer imaging systems. Bio-inspired modeling offers a promising way to elucidate the computational principles underlying color constancy and…

计算机视觉与模式识别 · 计算机科学 2026-04-23 Kai-Fu Yang , Fu-Ya Luo , Yong-Jie Li

The process of morphogenesis is an evolution of the shape of an organism together with the differentiation of its parts. This process encompasses numerous biological processes ranging from embryogenesis to regeneration following crisis such…

其他定量生物学 · 定量生物学 2019-09-23 N. Bessonov , O. Butuzova , A. Minarsky , R. Penner , C. Soule , A. Tosenberger , N. Morozova

Communication is essential for coordination among humans and animals. Therefore, with the introduction of intelligent agents into the world, agent-to-agent and agent-to-human communication becomes necessary. In this paper, we first study…

多智能体系统 · 计算机科学 2021-03-04 Varun Bhatt , Michael Buro

Automatically associating ICD codes with electronic health data is a well-known NLP task in medical research. NLP has evolved significantly in recent years with the emergence of pre-trained language models based on Transformers…

计算与语言 · 计算机科学 2023-04-07 Yakini Tchouka , Jean-François Couchot , David Laiymani , Philippe Selles , Azzedine Rahmani

During development, highly ordered structures emerge as cells collectively coordinate with each other. While recent advances have clarified how individual cells process and respond to external signals, understanding collective cellular…

生物物理 · 物理学 2026-02-05 Ashutosh Tripathi , Jörn Dunkel , Dominic J. Skinner

In this article, we show how to transform a colored de Bruijn graph (dBG) into a practical index for processing massive sets of sequencing reads. Similar to previous works, we encode an instance of a colored dBG of the set using BOSS and a…

数据结构与算法 · 计算机科学 2019-12-02 Diego Diaz-Domínguez

To afford flexible behaviour, the brain must build internal representations that mirror the structure of variables in the external world. For example, 2D space obeys rules: the same set of actions combine in the same way everywhere (step…

神经元与认知 · 定量生物学 2025-03-04 William Dorrell , Peter E. Latham , Timothy E. J. Behrens , James C. R. Whittington

One of the fundamental and most-studied algorithmic problems in distributed computing on networks is graph coloring, both in bounded-degree and in general graphs. Recently, the study of this problem has been extended in two directions.…

分布式、并行与集群计算 · 计算机科学 2021-09-14 Nicolas Bousquet , Laurent Feuilloley , Marc Heinrich , Mikaël Rabie

Neural Cellular Automata (NCAs) are bio-inspired dynamical systems in which identical cells iteratively apply a learned local update rule to self-organize into complex patterns, exhibiting regeneration, robustness, and spontaneous dynamics.…

计算机视觉与模式识别 · 计算机科学 2026-05-05 Ehsan Pajouheshgar , Yitao Xu , Ali Abbasi , Alexander Mordvintsev , Wenzel Jakob , Sabine Süsstrunk

We analyse the performance of simple distributed colouring algorithms under the assumption that the input graph is a hyperbolic random graph (HRG), a generative model capturing key properties of real-world networks such as power-law degree…

数据结构与算法 · 计算机科学 2025-07-23 Yannic Maus , Janosch Ruff

An extension of coupled maps is given which allows for the growth of the number of elements, and is inspired by the cell differentiation problem. The growth of elements is made possible first by clustering the phases, and then by…

adap-org · 物理学 2009-10-28 Kunihiko Kaneko

Probably the most fundamental processes for biological systems is their ability to create themselves through the use of cell division and cell differentiation. In this work a simple physical model is proposed for biological cell division.…

生物物理 · 物理学 2010-06-22 Eshel Faraggi

Many image-to-image translation problems are ambiguous, as a single input image may correspond to multiple possible outputs. In this work, we aim to model a \emph{distribution} of possible outputs in a conditional generative modeling…

计算机视觉与模式识别 · 计算机科学 2018-10-25 Jun-Yan Zhu , Richard Zhang , Deepak Pathak , Trevor Darrell , Alexei A. Efros , Oliver Wang , Eli Shechtman

Three-dimensional molecular generators based on diffusion models can now reach near-crystallographic accuracy, yet they remain fragmented across tasks. SMILES-only inputs, two-stage pretrain-finetune pipelines, and one-task-one-model…

生物大分子 · 定量生物学 2025-07-11 Dong Xu , Zhangfan Yang , Sisi Yuan , Jenna Xinyi Yao , Jiangqiang Li , Junkai Ji

Counting cells in fluorescent microscopy is a tedious, time-consuming task that researchers have to accomplish to assess the effects of different experimental conditions on biological structures of interest. Although such objects are…

计算机视觉与模式识别 · 计算机科学 2021-03-02 R. Morelli , L. Clissa , M. Dalla , M. Luppi , L. Rinaldi , A. Zoccoli

Grid cells, discovered more than a decade ago [5], are neurons in the brain of mammals that fire when the animal is located near certain specific points in its familiar terrain. Intriguingly, these points form, for a single cell, a…

神经元与认知 · 定量生物学 2016-06-16 Christos H. Papadimitriou