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Recent years have seen the development of many novel scoring tools for disease prognosis and prediction. To become accepted for use in clinical applications, these tools have to be validated on external data. In practice, validation is…

统计方法学 · 统计学 2022-12-06 Matthias Schmid , Tim Friede , Nadja Klein , Leonie Weinhold

This paper describes a compound Poisson-based random effects structure for modeling zero-inflated data. Data with large proportion of zeros are found in many fields of applied statistics, for example in ecology when trying to model and…

应用统计 · 统计学 2009-07-29 Marie-Pierre Etienne , Eric Parent , Benoit Hugues , Bernier Jacques

Estimators based on influence functions (IFs) have been shown to be effective in many settings, especially when combined with machine learning techniques. By focusing on estimating a specific target of interest (e.g., the average effect of…

统计方法学 · 统计学 2019-10-29 Aaron Fisher , Edward H. Kennedy

We study robust estimators of the mean of a probability measure $P$, called robust empirical mean estimators. This elementary construction is then used to revisit a problem of aggregation and a problem of estimator selection, extending…

统计理论 · 数学 2021-07-05 M. Lerasle , R. I. Oliveira

We consider a linear mixed-effects model with a clustered structure, where the parameters are estimated using maximum likelihood (ML) based on possibly unbalanced data. Inference with this model is typically done based on asymptotic theory,…

统计理论 · 数学 2021-03-30 Chih-Hao Chang , Hsin-Cheng Huang , Ching-Kang Ing

Doubly robust estimators of causal effects are a popular means of estimating causal effects. Such estimators combine an estimate of the conditional mean of the outcome given treatment and confounders (the so-called outcome regression) with…

统计方法学 · 统计学 2019-01-17 David Benkeser , Weixin Cai , Mark J van der Laan

Longitudinal studies are often subject to missing data. The ICH E9(R1) addendum addresses the importance of defining a treatment effect estimand with the consideration of intercurrent events. Jump-to-reference (J2R) is one classically…

统计方法学 · 统计学 2023-12-06 Siyi Liu , Shu Yang , Yilong Zhang , Guanghan , Liu

We describe a design-based framework for drawing causal inference in general randomized experiments. Causal effects are defined as linear functionals evaluated at unit-level potential outcome functions. Assumptions about the potential…

统计方法学 · 统计学 2025-08-15 Christopher Harshaw , Fredrik Sävje , Yitan Wang

Two-stage randomized experiments are becoming an increasingly popular experimental design for causal inference when the outcome of one unit may be affected by the treatment assignments of other units in the same cluster. In this paper, we…

统计方法学 · 统计学 2022-10-21 Zhichao Jiang , Kosuke Imai , Anup Malani

This paper presents uniform estimation and inference theory for a large class of nonparametric partitioning-based M-estimators. The main theoretical results include: (i) uniform consistency for convex and non-convex objective functions;…

统计理论 · 数学 2025-09-01 Matias D. Cattaneo , Yingjie Feng , Boris Shigida

Statisticians usually restrict regression to model relationships that are explicitly defined dependent and independent random variables; this paper outlines the newly developed method of non-response analysis and rotational analysis for…

统计方法学 · 统计学 2016-03-29 Rebecca D. Wooten

Measurement error is a pervasive challenge across many disciplines, yet its impact on sample size determination and the accuracy and precision of estimators regarding the association between an exposure and an outcome remains understudied…

统计方法学 · 统计学 2025-05-27 Honghyok Kim

A concentration index, a standardized covariance between a health variable and relative income ranks, is often used to quantify income-related health inequalities. There is a lack of formal approach to study the effect of an exposure, e.g.,…

统计方法学 · 统计学 2025-01-14 Mohammad Ghasempour , Xavier de Luna , Per E. Gustafsson

"Big data" gives markets access to previously unmeasured characteristics of individual agents. Policymakers must decide whether and how to regulate the use of this data. We study how new data affects incentives for agents to exert effort in…

理论经济学 · 经济学 2022-09-05 Annie Liang , Erik Madsen

A general random effects model is proposed that allows for continuous as well as discrete distributions of the responses. Responses can be unrestricted continuous, bounded continuous, binary, ordered categorical or given in the form of…

统计方法学 · 统计学 2024-04-30 Gerhard Tutz

Inspired by the complexity of certain real-world datasets, this article introduces a novel flexible linear spline index regression model. The model posits piecewise linear effects of an index on the response, with continuous changes…

统计方法学 · 统计学 2024-09-04 Lianqiang Qu , Long Lv , Meiling Hao , Liuquan Sun

Ordered response scales are ubiquitous in economics, but their interpretation rests on an untested assumption: that numerical labels reflect equal psychological intervals. The contribution of this paper is to provide a systematic assessment…

综合经济学 · 经济学 2025-09-03 Caspar Kaiser , Anthony Lepinteur

Robust M-estimation uses loss functions, such as least absolute deviation (LAD), quantile loss and Huber's loss, to construct its objective function, in order to for example eschew the impact of outliers, whereas the difficulty in analysing…

计量经济学 · 经济学 2023-01-18 Chaohua Dong , Jiti Gao , Yundong Tu , Bin Peng

One fundamental statistical question for research areas such as precision medicine and health disparity is about discovering effect modification of treatment or exposure by observed covariates. We propose a semiparametric framework for…

统计方法学 · 统计学 2020-08-04 Muxuan Liang , Menggang Yu

Standard measures of effect, including the risk ratio, the odds ratio, and the risk difference, are associated with a number of well-described shortcomings, and no consensus exists about the conditions under which investigators should…

统计方法学 · 统计学 2019-10-08 Anders Huitfeldt , Andrew Goldstein , Sonja A. Swanson