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Robustness and evolvability are essential properties to the evolution of biological networks. To determine if a biological network is robust and/or evolvable, it is required to compare its functions before and after mutations. However, this…

适应与自组织系统 · 物理学 2025-12-22 Hyobin Kim , Stalin Muñoz , Pamela Osuna , Carlos Gershenson

Antifragility is a property from which systems are able to resist stress and furthermore benefit from it. Even though antifragile dynamics is found in various real-world complex systems where multiple subsystems interact with each other,…

适应与自组织系统 · 物理学 2026-02-04 Hyobin Kim , Omar K. Pineda , Carlos Gershenson

Antifragility characterizes the benefit of a dynamical system derived from the variability in environmental perturbations. Antifragility carries a precise definition that quantifies a system's output response to input variability. Systems…

Most models of complex systems have been homogeneous, i.e., all elements have the same properties (spatial, temporal, structural, functional). However, most natural systems are heterogeneous: few elements are more relevant, larger,…

适应与自组织系统 · 物理学 2025-12-22 Amahury Jafet López-Díaz , Fernanda Sánchez-Puig , Carlos Gershenson

The area of Smart Power Grids needs to constantly improve its efficiency and resilience, to pro-vide high quality electrical power, in a resistant grid, managing faults and avoiding failures. Achieving this requires high component…

机器学习 · 计算机科学 2021-02-03 Pedro J. Rivera Torres , Carlos Gershenson García , Samir Kanaan Izquierdo

A system is called antifragile when damage acts as a constructive element improving the performance of a global function. In this paper, we analyze the emergence of antifragility in the movement of random walkers on networks with modular…

统计力学 · 物理学 2024-10-22 L. K. Eraso-Hernandez , A. P. Riascos

Regulatory networks (RNs) are a well-accepted modelling formalism in computational systems biology. The control of RNs is currently receiving a lot of attention because it provides a computational basis for cell reprogramming -- an…

系统与控制 · 电气工程与系统科学 2022-03-01 Luboš Brim , Samuel Pastva , David Šafránek , Eva Šmijáková

In this work, several random Boolean networks (RBN) are generated and analyzed from two characteristics: their time evolution diagram and their transition diagram. For this purpose, its randomness is estimated using three measures, of which…

信息论 · 计算机科学 2024-09-04 Manuel de J. Luevano , Alejandro Puga

This chapter introduces evolutionary antifragility as the time-scale interaction characteristics of a natural dynamic system. It describes the benefit derived from input distribution unevenness, based on the emergent system dynamics and its…

种群与进化 · 定量生物学 2025-04-25 Cristian Axenie , Roman Bauer , Oliver Lopez Corona , Elvia Ramirez-Carrillo , Ari Barnett , Jeffrey West

The optimal operation of transportation systems is often susceptible to unexpected disruptions. Many established control strategies reliant on mathematical models can struggle with real-world disruptions, leading to significant divergence…

系统与控制 · 电气工程与系统科学 2026-03-24 Linghang Sun , Michail A. Makridis , Alexander Genser , Cristian Axenie , Margherita Grossi , Anastasios Kouvelas

The complex dynamics of gene expression in living cells can be well-approximated using Boolean networks. The average sensitivity is a natural measure of stability in these systems: values below one indicate typically stable dynamics…

Emergence of robustness in biological networks is a paramount feature of evolving organisms, but a study of this property in vivo, for any level of representation such as Genetic, Metabolic, or Neuronal Networks, is a very hard challenge.…

分子网络 · 定量生物学 2012-10-18 Vitor H. P. Louzada , Fabrício M. Lopes , Ronaldo F. Hashimoto

When is it safe to approximate a complicated random Boolean network (RBN) as a simplified, easier to model RBN? When can static measures of network structure be reliably used to infer the network's dynamics? This simple experiment tests the…

适应与自组织系统 · 物理学 2010-05-20 Shaun Deaton , Seth Frey

The enhanced Bayesian network (eBN) methodology described in the companion paper facilitates the assessment of reliability and risk of engineering systems when information about the system evolves in time. We present the application of the…

应用统计 · 统计学 2012-03-28 Daniel Straub , Armen Der Kiureghian

This paper introduces a novel approach to quantifying ecological resilience in biological systems, particularly focusing on noisy systems responding to episodic disturbances with sudden adaptations. Incorporating concepts from…

定量方法 · 定量生物学 2024-12-24 Jorge M. Ramirez , Juan M. Restrepo , Valerio Lucarini , David Weston

We study two measures of the complexity of heterogeneous extended systems, taking random Boolean networks as prototypical cases. A measure defined by Shalizi et al. for cellular automata, based on a criterion for optimal statistical…

元胞自动机与格子气 · 物理学 2012-06-12 Xinwei Gong , Joshua E. S. Socolar

Random boolean networks are a model of genetic regulatory networks that has proven able to describe experimental data in biology. They not only reproduce important phenomena in cell dynamics, but they are also extremely interesting from a…

Reasonably large perturbations may push a power grid from its stable synchronous state into an undesirable state. Identifying vulnerabilities in power grids by studying power grid stability against such perturbations can aid in preventing…

适应与自组织系统 · 物理学 2025-08-26 Calvin Alvares , Soumitro Banerjee

We construct and investigate Boolean networks that follow a given reliable trajectory in state space, which is insensitive to fluctuations in the updating schedule, and which is also robust against noise. Robustness is quantified as the…

生物物理 · 物理学 2010-12-02 Christoph Schmal , Tiago P. Peixoto , Barbara Drossel

Now that Bayesian Networks (BNs) have become widely used, an appreciation is developing of just how critical an awareness of the sensitivity and robustness of certain target variables are to changes in the model. When time resources are…

统计方法学 · 统计学 2018-11-20 Sophia K. Wright , Jim Q. Smith
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