相关论文: Functional change in children with cerebral palsy
Clinical assessments for neuromuscular disorders, such as Spinal Muscular Atrophy (SMA) and Duchenne Muscular Dystrophy (DMD), continue to rely on subjective measures to monitor treatment response and disease progression. We introduce a…
Children and adults with cerebral palsy (CP) can have involuntary upper limb movements as a consequence of the symptoms that characterize their motor disability, leading to difficulties in communicating with caretakers and peers. We…
Compared to in-clinic balance training, in-home training is not as effective. This is, in part, due to the lack of feedback from physical therapists (PTs). Here, we analyze the feasibility of using trunk sway data and machine learning (ML)…
As our population ages, neurological impairments and degeneration of the musculoskeletal system yield gait abnormalities, which can significantly reduce quality of life. Gait rehabilitative therapy has been widely adopted to help patients…
Attention Deficit/Hyperactivity Disorder (ADHD) is one of the most common neurodevelopmental disorders in children and is characterised by inattention, impulsiveness and hyperactivity. While several studies have analysed the static…
Human brain function dynamically adjusts to ever-changing stimuli from the external environment. Studies characterizing brain functional reconfiguration are nevertheless scarce. Here we present a principled mathematical framework to…
The goal of the present study is to identify autism using machine learning techniques and resting-state brain imaging data, leveraging the temporal variability of the functional connections (FC) as the only information. We estimated and…
In early years of life, the cranium rapidly changes in size and shape to accommodate brain growth, primarily driven by mechanical stress from brain expansion. Developmental disorders such as premature fusion of sutures in craniosynostosis,…
Currently available musculoskeletal inverse-dynamics thoracolumbar spine models are entirely based on data from adults and might therefore not be applicable for simulations in children and adolescents. In addition, these models lack lower…
Autism spectrum disorder is a neuro-developmental disorder characterized by abnormalities of neural synchronization. In this study, functional near infrared spectroscopy (fNIRS) is used to study the difference in functional connectivity in…
Fundamental knowledge in activity recognition of individuals with motor disorders such as Parkinson's disease (PD) has been primarily limited to detection of steady-state/static tasks (sitting, standing, walking). To date, identification of…
This paper has been withdrawn by the authors due to insufficient or definition error(s) in the ethics approval protocol. Autism spectrum disorders (ASD) impact the cognitive, social, communicative and behavioral abilities of an individual.…
This research addressed whether interactions with social robots could facilitate joint attention of the autism spectrum disorder (ASD). Two conditions of initiators, namely 'Human' vs. 'Robot' were measured with 15 children with ASD and 15…
Early prediction of cerebral palsy is essential as it leads to early treatment and monitoring. Deep learning has shown promising results in biomedical engineering thanks to its capacity of modelling complicated data with its non-linear…
Children with unilateral cerebral palsy have movement impairments that are predominant to one of their upper extremities (UE) and are prone to a phenomenon named "developmental disregard", which is characterized by the neglect of their most…
A large database of brain imaging data from healthy, normal controls is useful to describe physiologic and pathologic structural changes at a population scale. In particular, these data can provide information about structural changes…
Musculoskeletal diseases and cognitive impairments in patients lead to difficulties in movement as well as negative effects on their psychological health. Clinical gait analysis, a vital tool for early diagnosis and treatment, traditionally…
Perinatal stroke (PS) is a serious condition that, if undetected and thus untreated, often leads to life-long disability, in particular Cerebral Palsy (CP). In clinical settings, Prechtl's General Movement Assessment (GMA) can be used to…
This study investigates the speech articulatory coordination in schizophrenia subjects exhibiting strong positive symptoms (e.g.hallucinations and delusions), using a time delay embedded correlation analysis. We show that the schizophrenia…
Physical growth traits can be naturally represented by continuous functions. In a large dataset of infancy growth patterns, we develop a practical approach to infer statistical associations between growth-trajectories and IQ performance in…