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Histopathology images are crucial to the study of complex diseases such as cancer. The histologic characteristics of nuclei play a key role in disease diagnosis, prognosis and analysis. In this work, we propose a sparse Convolutional…

计算机视觉与模式识别 · 计算机科学 2017-04-11 Le Hou , Vu Nguyen , Dimitris Samaras , Tahsin M. Kurc , Yi Gao , Tianhao Zhao , Joel H. Saltz

Nuclei instance segmentation in hematoxylin and eosin (H&E)-stained images plays an important role in automated histological image analysis, with various applications in downstream tasks. While several machine learning and deep learning…

计算机视觉与模式识别 · 计算机科学 2026-01-29 Nima Torbati , Anastasia Meshcheryakova , Ramona Woitek , Sepideh Hatamikia , Diana Mechtcheriakova , Amirreza Mahbod

This study explores the application of supervised and unsupervised autoencoders (AEs) to automate nuclei classification in clear cell renal cell carcinoma (ccRCC) images, a diagnostic task traditionally reliant on subjective visual grading…

图像与视频处理 · 电气工程与系统科学 2025-04-07 Fatemeh Javadian , Zahra Aminparast , Johannes Stegmaier , Abin Jose

Nuclear segmentation and classification within Haematoxylin & Eosin stained histology images is a fundamental prerequisite in the digital pathology work-flow. The development of automated methods for nuclear segmentation and classification…

计算机视觉与模式识别 · 计算机科学 2019-11-14 Simon Graham , Quoc Dang Vu , Shan E Ahmed Raza , Ayesha Azam , Yee Wah Tsang , Jin Tae Kwak , Nasir Rajpoot

Breast Cancer is a major cause of death worldwide among women. Hematoxylin and Eosin (H&E) stained breast tissue samples from biopsies are observed under microscopes for the primary diagnosis of breast cancer. In this paper, we propose a…

计算机视觉与模式识别 · 计算机科学 2018-07-26 Aditya Golatkar , Deepak Anand , Amit Sethi

Skin cancer is a crucial health issue that requires timely detection for higher survival rates. Traditional computer vision techniques face challenges in addressing the advanced variability of skin lesion features, a gap partially bridged…

图像与视频处理 · 电气工程与系统科学 2024-03-22 Sibasish Dhibar

We propose an unsupervised method using self-clustering convolutional adversarial autoencoders to classify prostate tissue as tumor or non-tumor without any labeled training data. The clustering method is integrated into the training of the…

计算机视觉与模式识别 · 计算机科学 2018-04-20 Wouter Bulten , Geert Litjens

In this paper, we develop a complete pipeline for stain normalization, segmentation, and classification of nuclei in hematoxylin and eosin (H&E) stained breast cancer histopathology images. In the first step, we use a CNN-based stain…

计算机视觉与模式识别 · 计算机科学 2018-11-12 Edwin Yuan , Junkyo Suh

Deep learning has gained significant attention in medical image segmentation. However, the limited availability of annotated training data presents a challenge to achieving accurate results. In efforts to overcome this challenge, data…

图像与视频处理 · 电气工程与系统科学 2024-08-16 Aghiles Kebaili , Jérôme Lapuyade-Lahorgue , Pierre Vera , Su Ruan

Histopathological diagnoses of tumors in tissue biopsy after Hematoxylin and Eosin (H&E) staining is the gold standard for oncology care. H&E staining is slow and uses dyes, reagents and precious tissue samples that cannot be reused.…

Unsupervised learning is becoming more and more important recently. As one of its key components, the autoencoder (AE) aims to learn a latent feature representation of data which is more robust and discriminative. However, most AE based…

机器学习 · 计算机科学 2019-04-02 Jingcai Guo , Song Guo

Autoencoders are fundamental tools in classical computing for unsupervised feature extraction, dimensionality reduction, and generative learning. The Quantum Autoencoder (QAE), introduced by Romero J.[2017 Quantum Sci. Technol. 2 045001],…

量子物理 · 物理学 2025-02-12 Li-An Lo , Li-Yi Hsu , En-Jui Kuo

Early detection and prognosis of breast cancer are feasible by utilizing histopathological grading of biopsy specimens. This research is focused on detection and grading of nuclear pleomorphism in histopathological images of breast cancer.…

计算机视觉与模式识别 · 计算机科学 2016-12-06 Pegah Faridi , Habibollah Danyali , Mohammad Sadegh Helfroush , Mojgan Akbarzadeh Jahromi

Nuclei instance segmentation plays an important role in the analysis of Hematoxylin and Eosin (H&E)-stained images. While supervised deep learning (DL)-based approaches represent the state-of-the-art in automatic nuclei instance…

图像与视频处理 · 电气工程与系统科学 2021-03-25 Amirreza Mahbod , Gerald Schaefer , Benjamin Bancher , Christine Löw , Georg Dorffner , Rupert Ecker , Isabella Ellinger

Identification and quantification of nuclei in colorectal cancer haematoxylin \& eosin (H\&E) stained histology images is crucial to prognosis and patient management. In computational pathology these tasks are referred to as nuclear…

定量方法 · 定量生物学 2022-03-08 Muhammad Dawood , Raja Muhammad Saad Bashir , Srijay Deshpande , Manahil Raza , Adam Shephard

Masked image modelling (MIM) is a powerful self-supervised representation learning paradigm, whose potential has not been widely demonstrated in medical image analysis. In this work, we show the capacity of MIM to capture rich semantic…

计算机视觉与模式识别 · 计算机科学 2023-06-30 Piotr Wójcik , Hussein Naji , Adrian Simon , Reinhard Büttner , Katarzyna Bożek

Cancer is still one of the most devastating diseases of our time. One way of automatically classifying tumor samples is by analyzing its derived molecular information (i.e., its genes expression signatures). In this work, we aim to…

机器学习 · 计算机科学 2020-01-16 Mafalda Falcao Ferreira , Rui Camacho , Luis F. Teixeira

Automatic nuclei segmentation and classification play a vital role in digital pathology. However, previous works are mostly built on data with limited diversity and small sizes, making the results questionable or misleading in actual…

图像与视频处理 · 电气工程与系统科学 2023-05-31 Kai Yao , Kaizhu Huang , Jie Sun , Amir Hussain

In computational pathology, automatic nuclei instance segmentation plays an essential role in whole slide image analysis. While many computerized approaches have been proposed for this task, supervised deep learning (DL) methods have shown…

We present a self-supervised algorithm for several classification tasks within hematoxylin and eosin (H&E) stained images of breast cancer. Our method is robust to stain variations inherent to the histology images acquisition process, which…

计算机视觉与模式识别 · 计算机科学 2023-09-08 Alexandre Tiard , Alex Wong , David Joon Ho , Yangchao Wu , Eliram Nof , Alvin C. Goh , Stefano Soatto , Saad Nadeem
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