相关论文: Can diffusion alone explain brain-wide distributio…
A novel approach is adopted to model cerebrospinal fluid (CSF) flow in human perivascular spaces (PVSs) surrounding brain-penetrating arteries. It is proposed that the outer PVS boundary oscillates due to brain pulsations and the arterial…
Purpose: Oscillating gradient spin-echo (OGSE) diffusion MRI provides information about the microstructure of biological tissues via the frequency dependence of the apparent diffusion coefficient (ADC). ADC dependence on OGSE frequency has…
Previous work indicates evidence that cerebrospinal fluid (CSF) plays a crucial role in brain waste clearance processes, and that altered flow patterns are associated with various diseases of the central nervous system. In this study, we…
The glymphatic system (GS) is a transit passage that facilitates brain metabolic waste removal and its dysfunction has been associated with neurodegenerative diseases such as Alzheimer's disease. The GS has been studied by acquiring…
Despite extensive progress in characterizing the emergent behavior of active matter, the microscopic origins of self-diffusion in interacting active systems remain poorly understood. Here, we develop a framework that quantitatively links…
It has been shown that light speckle fluctuations provide a means for noninvasive measurements of cerebral blood flow index (CBFi). While conventional Diffuse Correlation Spectroscopy (DCS) provides marginal brain sensitivity for CBFi in…
The coupling of sediment transport with the flow that drives it allows rivers to shape their own bed. Cross-stream fluxes of sediment play a crucial, yet poorly understood, role in this process. Here, we track particles in a laboratory…
The different active roles of neurons and astrocytes during neuronal activation are associated with the metabolic processes necessary to supply the energy needed for their respective tasks at rest and during neuronal activation. Metabolism,…
MRI measurements from a decade-old study of the physical properties of brain tissue observed a dynamic, pulsating fluid flow in the interstitial spaces of the brain attributed to the cardiac cycle. The effects of this cyclic flow pattern on…
The transport equation of active motion is generalised to consider time-fractional dynamics for describing the anomalous diffusion of self-propelled particles observed in many different systems. In the present study, we consider an…
We consider the diffusion-advection problem in two simple cellular flow models (often invoked as examples for subdiffusive tracer's motion) and concentrate on the intermediate time range, in which the tracer's motion indeed may show…
Brain network analysis is essential for diagnosing and intervention for Alzheimer's disease (AD). However, previous research relied primarily on specific time-consuming and subjective toolkits. Only few tools can obtain the structural brain…
Alzheimer's Disease (AD) is a neurodegenerative condition characterized by diverse progression rates among individuals, with changes in cortical thickness (CTh) closely linked to its progression. Accurately forecasting CTh trajectories can…
Cerebral perfusion plays a crucial role in maintaining brain function and is tightly coupled with neuronal activity. While previous studies have examined cerebral perfusion trajectories across development and aging, precise characterization…
Perfusion MRI is an important modality in many brain imaging protocols, since it probes cerebrovascular changes in aging and many diseases; however, it may not be always available. Here we introduce a method that seeks to estimate regional…
Brain is one of the most energy demanding organs in mammals, and its total metabolic rate scales with brain volume raised to a power of around 5/6. This value is significantly higher than the more common exponent 3/4 relating whole body…
The analysis and design of advection-diffusion based molecular communication (MC) systems in cylindrical environments is of particular interest for applications such as micro-fluidics and targeted drug delivery in blood vessels. Therefore,…
Alzheimer's disease is the most common cause of dementia, yet difficult to accurately diagnose without the use of invasive techniques, particularly at the beginning of the disease. This work addresses the classification and analysis of…
A theoretical analysis of the anomalous diffusion transport mechanism suggests a possible connection between wall current drain and magnetic flux through the orbital trajectories of charged particles in a plasma submitted to a strong…
A ubiquitous observation in cell biology is that diffusion of macromolecules and organelles is anomalous, and a description simply based on the conventional diffusion equation with diffusion constants measured in dilute solution fails. This…