相关论文: Network models for characterization of trabecular …

Designing strong and robust bio-inspired structures requires an understanding of how function arises from the architecture and geometry of materials found in nature. We draw from trabecular bone, a lightweight bone tissue that exhibits a…

Purpose: We present a new morphometric measure of trabecular bone microarchitecture, called mean node strength (NdStr), which is part of a newly developed approach called long range node-strut analysis. Our general aim is to describe and…

As global population aging intensifies, there is growing interest in the study of biological age. Bones have long been used to evaluate biological age, and the decline in bone density with age is a well-recognized phenomenon in adults.…

Bone adaptation models are often solved in the forward direction, meaning that the response of bone to a given set of loads is determined by running a bone tissue adaptation model. The model is generally solved using a numerical technique…

In this chapter we explore and evaluate methods for trabecular bone characterization and osteoporosis diagnosis with increased interest in sparse approximations. We first describe texture representation and classification techniques,…

Natural hard composites like human bone possess a combination of strength and toughness that exceeds that of their constituents and of many engineered composites. This augmentation is attributed to their complex hierarchical structure,…

Inner porous regions play a critical role in the load bearing capability of large bones.We show that an extension of disordered elastic networks [Chung et. al., Phys. Rev. B, {\bf 54}, 15094 (1996)] exhibits analogs of several known…

This article describes the application of recently introduced complex networks concepts and methods to the characterization and analysis of cortical bone structure. Three-dimensional reconstructions of the system of channels underlying bone…

Exploring the structural topology of genome-based large-scale metabolic network is essential for investigating possible relations between structure and functionality. Visualization would be helpful for obtaining immediate information about…

Plain radiography is the most common modality to assess the stage of osteoarthritis. Our aims were to assess the relationship of radiography-based bone density and texture between radiographs with minimal and clinical post-processing, and…

Disordered networks of fragile elastic elements have been proposed as a model of inner porous regions of large bones [Gunaratne et.al., cond-mat/0009221, http://xyz.lanl.gov]. It is shown that the ratio $\Gamma$ of responses of such a…

Diffusion Magnetic Resonance Imaging (MRI) exploits the anisotropic diffusion of water molecules in the brain to enable the estimation of the brain's anatomical fiber tracts at a relatively high resolution. In particular, tractographic…

Cortical bone is a tough biological material composed of tube-like osteons embedded in the organic matrix surrounded by weak interfaces known as cement lines. The cement lines provide a microstructurally preferable crack path, hence…

Vascular networks play a crucial role in understanding brain functionalities. Brain integrity and function, neuronal activity and plasticity, which are crucial for learning, are actively modulated by their local environments, specifically…

We propose a 3D neural network with specific loss functions for quantitative computed tomography (QCT) noise reduction to compute micro-structural parameters such as tissue mineral density (TMD) and bone volume ratio (BV/TV) with…

Purpose: The purpose is to design a novelty automatic diagnostic method for osteoporosis screening by using the potential capability of convolutional neural network (CNN) in feature representation and extraction, which can be incorporated…

We introduce a continuous modeling approach which combines elastic responds of the trabecular bone structure, the concentration of signaling molecules within the bone and a mechanism how this concentration at the bone surface is used for…

Disordered networks of fragile elastic elements have been proposed as a model for inner porous regions of large bones [Gunaratne et.al., cond-mat/0009221]. In numerical studies, weakening of such networks is seen to be accompanied by…

Bone fragility and fracture caused by osteoporosis or injury are prevalent in adults over the age of 50 and can reduce their quality of life. Hence, predicting the biomechanical bone strength, specifically of the proximal femur, through…

Networks of elastic beams can deform either by stretching or bending of their members. The primary mode of deformation (bending or stretching) crucially depends on the specific details of the network architecture. In order to shed light on…