相关论文: Network models for characterization of trabecular …
Osteoporosis causes progressive loss of bone density and strength, causing a more elevated risk of fracture than in normal healthy bones. It is estimated that some 1 in 3 women and 1 in 5 men over the age of 50 will experience osteoporotic…
We present a fiber-distributed model of the reinforcing collagen of the human cornea. The model describes the basic connections between the components of the tissue by defining an elementary block (cell) and upscaling it to the physical…
Vertebral body compression fractures are early signs of osteoporosis. Though these fractures are visible on Computed Tomography (CT) images, they are frequently missed by radiologists in clinical settings. Prior research on automatic…
The organization in brain networks shows highly modular features with weak inter-modular interaction. The topology of the networks involves emergence of modules and sub-modules at different levels of constitution governed by fractal laws.…
Disordered soft materials, such as fibrous networks in biological contexts exhibit a nonlinear elastic response. We study such nonlinear behavior with a minimal model for networks on lattice geometries with simple Hookian elements with…
Bone adapts in response to its mechanical environment. This evolution of bone density is one of the most important mechanisms for developing fracture resistance. A finite element framework for simulating bone adaptation, commonly called…
We employ a mathematical model to analyze stress chains in thermoplastic elastomers (TPEs) with a microphase-separated spherical structure composed of triblock copolymers. The model represents stress chains during uniaxial and biaxial…
Disordered fibrous networks are ubiquitous in nature as major structural components of living cells and tissues. The mechanical stability of networks generally depends on the degree of connectivity: only when the average number of…
3D ultrasound imaging shows great promise for scoliosis diagnosis thanks to its low-costing, radiation-free and real-time characteristics. The key to accessing scoliosis by ultrasound imaging is to accurately segment the bone area and…
A trust network is a social network in which edges represent the trust relationship between two nodes in the network. In a trust network, a fundamental question is how to assess and compute the bias and prestige of the nodes, where the bias…
Convexity in a network (graph) has been recently defined as a property of each of its subgraphs to include all shortest paths between the nodes of that subgraph. It can be measured on the scale [0, 1] with 1 being assigned to fully convex…
The mineralized collagen fibril is the main building block of hard tissues and it directly affects the macroscopic mechanics of biological tissues such as bone. The mechanical behavior of the fibril itself is determined by its structure:…
This article discusses how the individual morphological properties of basic objects (e.g. neurons, molecules and aggregates), jointly with their particular spatial distribution, can determine the connectivity and dynamics of systems…
MRI-based modeling of brain networks has been widely used to understand functional and structural interactions and connections among brain regions, and factors that affect them, such as brain development and disease. Graph mining on brain…
The mechanical properties of vertebrate bone are largely determined by a process which involves the complex interplay of three different cell types. This process is called {\it bone remodeling}, and occurs asynchronously at multiple sites…
The network topology can be described by the number of nodes and the interconnections among them. The degree of a node in a network is the number of connections it has to other nodes and the degree distribution is the probability…
Purpose: Diffusion weighted MRI (dMRI) and its models of neural structure provide insight into human brain organization and variations in white matter. A recent study by McMaster, et al. showed that complex graph measures of the connectome,…
We develop an agent-based model of vasculogenesis, the de novo formation of blood vessels. Endothelial cells in the vessel network are viewed as linearly elastic spheres and are of two types: vessel elements are contained within the…
Networks of elastic fibers are ubiquitous in biological systems and often provide mechanical stability to cells and tissues. Fiber reinforced materials are also common in technology. An important characteristic of such materials is their…
As an intuitive description of complex physical, social, or brain systems, complex networks have fascinated scientists for decades. Recently, to abstract a network's structural and dynamical attributes for utilization, network…