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We propose a semiparametric framework for causal inference with right-censored survival outcomes and many weak invalid instruments, motivated by Mendelian randomization in biobank studies where classical methods may fail. We adopt an…

统计方法学 · 统计学 2025-10-06 Qiushi Bu , Wen Su , Xingqiu Zhao , Zhonghua Liu

In this paper, we introduce new parametric and semiparametric regression techniques for a recurrent event process subject to random right censoring. We develop models for the cumula- tive mean function and provide asymptotically normal…

统计理论 · 数学 2015-03-17 Olivier Bouaziz , Ségolen Geffray , Olivier Lopez

Accurate and precise estimates of the under-5 mortality rate (U5MR) are an important health summary for countries. However, full survival curves allow us to better understand the pattern of mortality in children under five. Modern…

统计方法学 · 统计学 2024-08-19 Taylor Okonek , Katherine Wilson , Jon Wakefield

Causal inference across multiple data sources offers a promising avenue to enhance the generalizability and replicability of scientific findings. However, data integration methods for time-to-event outcomes, common in biomedical research,…

统计方法学 · 统计学 2025-05-16 Yi Liu , Alexander W. Levis , Ke Zhu , Shu Yang , Peter B. Gilbert , Larry Han

This paper explores the effects of simulated moments on the performance of inference methods based on moment inequalities. Commonly used confidence sets for parameters are level sets of criterion functions whose boundary points may depend…

计量经济学 · 经济学 2018-04-12 Hiroaki Kaido , Jiaxuan Li , Marc Rysman

Many epidemiological and clinical studies aim at analyzing a time-to-event endpoint. A common complication is right censoring. In some cases, it arises because subjects are still surviving after the study terminates or move out of the study…

统计方法学 · 统计学 2024-01-10 Andrew Ying

Stochastic epidemic models can estimate infection and removal rates, and derived quantities such as the basic reproductive number ($R_0$), when both infection and removal times are observed. In practice, however, removal times are often…

统计方法学 · 统计学 2026-03-24 Seth D. Temple , Jonathan Terhorst

While non-invasive sampling is more and more commonly used in capture-recapture (CR) experiments, it carries a higher risk of misidentifications than direct observations. As a consequence, one must screen the data to retain only the…

定量方法 · 定量生物学 2023-04-04 Rémi Fraysse , Rémi Choquet , Carlo Costantini , Roger Pradel

We consider the problem of estimating the joint distribution function of the event time and a continuous mark variable based on censored data. More specifically, the event time is subject to current status censoring and the continuous mark…

统计理论 · 数学 2011-09-07 Piet Groeneboom , Geurt Jongbloed , Birgit Witte

Most work in neural networks focuses on estimating the conditional mean of a continuous response variable given a set of covariates.In this article, we consider estimating the conditional distribution function using neural networks for both…

统计方法学 · 统计学 2022-07-07 Bingqing Hu , Bin Nan

Interval censored data commonly arise in medical studies when the event time of interest is only known to lie within an interval. In the presence of a cure subgroup, conventional mixture cure models typically assume a logistic model for the…

统计方法学 · 统计学 2026-01-21 Xiaoru Huang , Tonghui Yu , Xiaoyu Liu

Numerous statistical methods have been developed to explore genomic imprinting and maternal effects, which are causes of parent-of-origin patterns in complex human diseases. However, most of them either only model one of these two…

统计方法学 · 统计学 2024-01-02 Pooya Aavani , Alexandre Trindade , Fangyuan Zhang

A linear mixed-effects (LME) model is proposed for modelling and forecasting single and multi-population age-specific death rates (ASDRs). The innovative approach that we take in this study treats age, the interaction between gender and…

应用统计 · 统计学 2025-11-18 Reza Dastranj , Martin Kolar

Recurrent events are common in clinical, healthcare, social and behavioral studies. A recent analysis framework for potentially censored recurrent event data is to construct a censored longitudinal data set consisting of times to the first…

应用统计 · 统计学 2025-02-11 Abigail Loe , Susan Murray , Zhenke Wu

Assessing the causal effect of time-varying exposures on recurrent event processes is challenging in the presence of a terminating event. Our objective is to estimate both the short-term and delayed marginal causal effects of exposures on…

统计方法学 · 统计学 2025-06-10 Daniel Mork , Robert L. Strawderman , Michelle Audirac , Francesca Dominici , Ashkan Ertefaie

We introduce a self-censoring model for multivariate nonignorable nonmonotone missing data, where the missingness process of each outcome is affected by its own value and is associated with missingness indicators of other outcomes, while…

统计方法学 · 统计学 2022-10-03 Yilin Li , Wang Miao , Ilya Shpitser , Eric J. Tchetgen Tchetgen

Accurate time-to-event prediction is integral to decision-making, informing medical guidelines, hiring decisions, and resource allocation. Survival analysis, the quantitative framework used to model time-to-event data, accounts for patients…

机器学习 · 计算机科学 2025-08-08 Vincent Jeanselme , Brian Tom , Jessica Barrett

Stochastic processes often exhibit sudden systematic changes in pattern a short time before certain failure events. Examples include increase in medical costs before death and decrease in CD4 counts before AIDS diagnosis. To study such…

应用统计 · 统计学 2010-11-17 Kwun Chuen Gary Chan , Mei-Cheng Wang

Objective: Many low-severity crashes are not reported due to sampling criteria, introducing missing not at random (MNAR) bias. If not addressed, MNAR bias can lead to inaccurate safety analyses. This paper illustrates a statistical method…

应用统计 · 统计学 2025-03-10 Alberto Morando

We propose a censored quantile regression estimator motivated by unbiased estimating equations. Under the usual conditional independence assumption of the survival time and the censoring time given the covariates, we show that the proposed…

统计理论 · 数学 2013-02-04 Chenlei Leng , Xingwei Tong