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相关论文: Causal isotonic regression

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Existing statistical methods in causal inference often assume the positivity condition, where every individual has some chance of receiving any treatment level regardless of covariates. This assumption could be violated in observational…

统计方法学 · 统计学 2025-01-22 Yikun Zhang , Yen-Chi Chen , Alexander Giessing

The causal dose response curve is commonly selected as the statistical parameter of interest in studies where the goal is to understand the effect of a continuous exposure on an outcome.Most of the available methodology for statistical…

Statistical methods for causal inference with continuous treatments mainly focus on estimating the mean potential outcome function, commonly known as the dose-response curve. However, it is often not the dose-response curve but its…

统计方法学 · 统计学 2025-04-21 Yikun Zhang , Yen-Chi Chen

We study nonparametric inference for the causal dose-response (or treatment effect) curve when the treatment variable is continuous rather than binary or discrete. We do this by developing doubly robust confidence intervals for the…

统计方法学 · 统计学 2025-08-13 Charles R. Doss

Univariate isotonic regression (IR) has been used for nonparametric estimation in dose-response and dose-finding studies. One undesirable property of IR is the prevalence of piecewise-constant stretches in its estimates, whereas the…

统计方法学 · 统计学 2017-01-24 Assaf P. Oron , Nancy Flournoy

We consider a general monotone regression estimation where we allow for independent and dependent regressors. We propose a modification of the classical isotonic least squares estimator and establish its rate of convergence for the…

统计理论 · 数学 2018-05-07 Konstantinos Fokianos , Anne Leucht , Michael H. Neumann

We consider the problem of estimating a dose-response curve. Continuous treatments arise often in practice, e.g. in the form of time spent on an operation, distance traveled to a location or dosage of a drug. Letting $A$ denote a continuous…

统计方法学 · 统计学 2026-04-14 Matteo Bonvini , Edward H. Kennedy

Existing causal methods for time-varying exposure and time-varying confounding focus on estimating the average causal effect of a time-varying binary treatment on an end-of-study outcome, offering limited tools for characterizing marginal…

统计方法学 · 统计学 2026-01-21 Yu Luo , Kuan Liu , Ramandeep Singh , Daniel J. Graham

In this article, we study nonparametric inference for a covariate-adjusted regression function. This parameter captures the average association between a continuous exposure and an outcome after adjusting for other covariates. In…

统计方法学 · 统计学 2023-12-18 Kenta Takatsu , Ted Westling

An accurate estimation of the dose-response relationship is important to determine the optimal dose. For this purpose, a dose finding trial in which subjects are randomized to a few fixed dose levels is the most commonly used design. Often,…

统计方法学 · 统计学 2025-08-07 Jixian Wang , Zhiwei Zhang , Ram Tiwari

We propose simple nonparametric estimators for mediated and time-varying dose response curves based on kernel ridge regression. By embedding Pearl's mediation formula and Robins' g-formula with kernels, we allow treatments, mediators, and…

统计方法学 · 统计学 2025-03-18 Rahul Singh , Liyuan Xu , Arthur Gretton

We propose causal isotonic calibration, a novel nonparametric method for calibrating predictors of heterogeneous treatment effects. Furthermore, we introduce cross-calibration, a data-efficient variant of calibration that eliminates the…

机器学习 · 统计学 2023-06-07 Lars van der Laan , Ernesto Ulloa-Pérez , Marco Carone , Alex Luedtke

The method of instrumental variables provides a fundamental and practical tool for causal inference in many empirical studies where unmeasured confounding between the treatments and the outcome is present. Modern data such as the genetical…

统计方法学 · 统计学 2022-10-28 Ziang Niu , Yuwen Gu , Wei Li

We propose a one-to-many matching estimator of the average treatment effect based on propensity scores estimated by isotonic regression. This approach is predicated on the assumption of monotonicity in the propensity score function, a…

计量经济学 · 经济学 2025-01-27 Mengshan Xu , Taisuke Otsu

We consider nonparametric estimation of a regression curve when the data are observed with multiplicative distortion which depends on an observed confounding variable. We suggest several estimators, ranging from a relatively simple one that…

统计理论 · 数学 2016-01-13 Aurore Delaigle , Peter Hall , Wen-Xin Zhou

Flexible estimation of the mean outcome under a treatment regimen (i.e., value function) is the key step toward personalized medicine. We define our target parameter as a conditional value function given a set of baseline covariates which…

统计理论 · 数学 2023-09-29 Ashkan Ertefaie , Luke Duttweiler , Brent A. Johnson , Mark J. van der Laan

Long-term causal inference has drawn increasing attention in many scientific domains. Existing methods mainly focus on estimating average long-term causal effects by combining long-term observational data and short-term experimental data.…

机器学习 · 计算机科学 2025-03-04 Weilin Chen , Ruichu Cai , Junjie Wan , Zeqin Yang , José Miguel Hernández-Lobato

This paper constructs a doubly robust estimator for continuous dose-response estimation. An outcome regression model is augmented with a set of inverse generalized propensity score covariates to correct for potential misspecification bias.…

统计理论 · 数学 2015-06-17 Daniel J. Graham , Emma J. McCoy , David A. Stephens

Estimating and obtaining reliable inference for the marginally adjusted causal dose-response curve for continuous treatments without relying on parametric assumptions is a well-known statistical challenge. Parametric models risk introducing…

统计方法学 · 统计学 2025-08-29 Junming Shi , Wenxin Zhang , Alan E. Hubbard , Mark van der Laan

Weighted estimators are commonly used for estimating exposure effects in observational settings to establish causal relations. These estimators have a long history of development when the exposure of interest is binary and where the weights…

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