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In the genomic era, the identification of gene signatures associated with disease is of significant interest. Such signatures are often used to predict clinical outcomes in new patients and aid clinical decision-making. However, recent…

统计方法学 · 统计学 2019-03-27 Naim U. Rashid , Quefeng Li , Jen Jen Yeh , Joseph G. Ibrahim

AI-generated text detectors have recently gained adoption in educational and professional contexts. Prior research has uncovered isolated cases of bias, particularly against English Language Learners (ELLs) however, there is a lack of…

人工智能 · 计算机科学 2025-12-15 Priyam Basu , Yunfeng Zhang , Vipul Raheja

Large, annotated datasets are not widely available in medical image analysis due to the prohibitive time, costs, and challenges associated with labelling large datasets. Unlabelled datasets are easier to obtain, and in many contexts, it…

计算机视觉与模式识别 · 计算机科学 2022-08-02 Raghav Mehta , Changjian Shui , Brennan Nichyporuk , Tal Arbel

Identifying heterogeneity in a population's response to a health or policy intervention is crucial for evaluating and informing policy decisions. We propose a novel heterogeneous treatment effect estimator in the difference-in-differences…

统计方法学 · 统计学 2021-08-24 Xinkun Nie , Chen Lu , Stefan Wager

In recent years new cancer treatments improved survival in multiple histologies. Some of these therapeutics, and in particular treatment combinations, are often associated with severe treatment-related adverse events (AEs). It is therefore…

应用统计 · 统计学 2022-03-10 Steffen Ventz , Lorenzo Trippa

This research introduces the Theory of Partial Symmetry Enforced Attention Decomposition (PSEAD), a new and rigorous group-theoretic framework designed to seamlessly integrate local symmetry awareness into the core architecture of…

其他计算机科学 · 计算机科学 2026-02-19 Daniel Ayomide Olanrewaju

Genetic risk prediction is an important component of individualized medicine, but prediction accuracies remain low for many complex diseases. A fundamental limitation is the sample sizes of the studies on which the prediction algorithms are…

统计方法学 · 统计学 2017-06-20 Sihai Dave Zhao

EEG based multi-dimension emotion recognition has attracted substantial research interest in human computer interfaces. However, the high dimensionality of EEG features, coupled with limited sample sizes, frequently leads to classifier…

人机交互 · 计算机科学 2025-08-08 Tianze Yu , Junming Zhang , Wenjia Dong , Xueyuan Xu , Li Zhuo

Individualized treatment rules (ITR) can improve health outcomes by recognizing that patients may respond differently to treatment and assigning therapy with the most desirable predicted outcome for each individual. Flexible and efficient…

统计方法学 · 统计学 2017-09-25 Brent R. Logan , Rodney Sparapani , Robert E. McCulloch , Purushottam W. Laud

Subgroup selection in clinical trials is essential for identifying patient groups that react differently to a treatment, thereby enabling personalised medicine. In particular, subgroup selection can identify patient groups that respond…

In contrast to fully-supervised models, self-supervised representation learning only needs a fraction of data to be labeled and often achieves the same or even higher downstream performance. The goal is to pre-train deep neural networks on…

机器学习 · 计算机科学 2025-04-09 Friederike Baier , Sebastian Mair , Samuel G. Fadel

Despite the massive costs and widespread harms of substance use, most individuals with substance use disorders (SUDs) receive no treatment at all. Digital therapeutics platforms are an emerging low-cost and low-barrier means of extending…

系统与控制 · 电气工程与系统科学 2025-04-03 Eric Pulick , Yonatan Mintz

Patient triage at emergency departments (EDs) is necessary to prioritize care for patients with critical and time-sensitive conditions. Different tools are used for patient triage and one of the most common ones is the emergency severity…

人工智能 · 计算机科学 2025-07-08 Abdulaziz Ahmed , Mohammed Al-Maamari , Mohammad Firouz , Dursun Delen

We introduce a new task called Adaptable Error Detection (AED), which aims to identify behavior errors in few-shot imitation (FSI) policies based on visual observations in novel environments. The potential to cause serious damage to…

机器人学 · 计算机科学 2024-10-23 Jia-Fong Yeh , Kuo-Han Hung , Pang-Chi Lo , Chi-Ming Chung , Tsung-Han Wu , Hung-Ting Su , Yi-Ting Chen , Winston H. Hsu

Precision medicine tailors treatments to individual patient characteristics, which is especially valuable for conditions like obstructive sleep apnea (OSA), where treatment responses vary widely. Traditional trials often overlook subgroup…

应用统计 · 统计学 2025-03-20 Lara Maleyeff , Shirin Golchi , Erica E. M. Moodie , R. John Kimoff

We consider the problem of selecting the optimal subgroup to treat when data on covariates is available from a randomized trial or observational study. We distinguish between four different settings including (i) treatment selection when…

统计方法学 · 统计学 2018-02-28 Tyler J. VanderWeele , Alex R. Luedtke , Mark J. van der Laan , Ronald C. Kessler

We propose an experience-guided cascaded multi-agent framework for Breast Ultrasound Screening and Diagnosis, called BUSD-Agent, that aims to reduce diagnostic escalation and unnecessary biopsy referrals. Our framework models screening and…

计算机视觉与模式识别 · 计算机科学 2026-03-02 Pramit Saha , Mohammad Alsharid , Joshua Strong , J. Alison Noble

This study designs an adaptive experiment for efficiently estimating average treatment effects (ATEs). In each round of our adaptive experiment, an experimenter sequentially samples an experimental unit, assigns a treatment, and observes…

统计方法学 · 统计学 2024-06-21 Masahiro Kato , Akihiro Oga , Wataru Komatsubara , Ryo Inokuchi

Adaptive experiments automatically optimize their design throughout the data collection process, which can bring substantial benefits compared to conventional experimental settings. Potential applications include, among others: computerized…

统计方法学 · 统计学 2026-04-01 Lucas Gautheron , Nori Jacoby , Peter Harrison

Recently, there has been great interest in estimating the conditional average treatment effect using flexible machine learning methods. However, in practice, investigators often have working hypotheses about effect heterogeneity across…

统计方法学 · 统计学 2023-09-13 Chan Park , Hyunseung Kang
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