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Medical tasks such as diagnosis and treatment planning require precise and complex reasoning, particularly in life-critical domains. Unlike mathematical reasoning, medical reasoning demands meticulous, verifiable thought processes to ensure…

Large language models (LLMs) have recently emerged as powerful tools, finding many medical applications. LLMs' ability to coalesce vast amounts of information from many sources to generate a response-a process similar to that of a human…

Large language models (LLMs) are increasingly used in the mental health domain, yet it remains unclear how well they capture related biomedical knowledge and how reliably they apply it to clinically salient structured judgments. Here, we…

To improve the reliability of Large Language Models (LLMs) in clinical applications, retrieval-augmented generation (RAG) is extensively applied to provide factual medical knowledge. However, beyond general medical knowledge from open-ended…

计算与语言 · 计算机科学 2025-05-29 Justice Ou , Tinglin Huang , Yilun Zhao , Ziyang Yu , Peiqing Lu , Rex Ying

In recent years, we have witnessed the proliferation of knowledge graphs (KG) in various domains, aiming to support applications like question answering, recommendations, etc. A frequent task when integrating knowledge from different KGs is…

数据库 · 计算机科学 2023-06-08 Nikolaos Fanourakis , Vasilis Efthymiou , Dimitris Kotzinos , Vassilis Christophides

Knowledge graph (KG) embedding has been used to benefit the diagnosis of animal diseases by analyzing electronic medical records (EMRs), such as notes and veterinary records. However, learning representations to capture entities and…

人工智能 · 计算机科学 2023-09-08 Van Thuy Hoang , Sang Thanh Nguyen , Sangmyeong Lee , Jooho Lee , Luong Vuong Nguyen , O-Joun Lee

Increasingly large electronic health records (EHRs) provide an opportunity to algorithmically learn medical knowledge. In one prominent example, a causal health knowledge graph could learn relationships between diseases and symptoms and…

应用统计 · 统计学 2019-10-04 Irene Y. Chen , Monica Agrawal , Steven Horng , David Sontag

Electronic health records (EHRs) enable strong clinical prediction, but explanations are often coarse and hard to use for patient-level decisions. We propose a knowledge graph (KG)-guided chain-of-thought (CoT) framework for visit-level…

人工智能 · 计算机科学 2026-03-03 Ruiyu Wang , Tuan Vinh , Ran Xu , Yuyin Zhou , Jiaying Lu , Carl Yang , Francisco Pasquel

Drug discovery and development is a complex and costly process. Machine learning approaches are being investigated to help improve the effectiveness and speed of multiple stages of the drug discovery pipeline. Of these, those that use…

Due to the increasing adoption of electronic health records (EHR), large scale EHRs have become another rich data source for translational clinical research. Despite its potential, deriving generalizable knowledge from EHR data remains…

机器学习 · 统计学 2023-06-01 Junwei Lu , Jin Yin , Tianxi Cai

Background Knowledge graphs (KGs), especially medical knowledge graphs, are often significantly incomplete, so it necessitating a demand for medical knowledge graph completion (MedKGC). MedKGC can find new facts based on the exited…

人工智能 · 计算机科学 2021-05-31 Yinyu Lan , Shizhu He , Xiangrong Zeng , Shengping Liu , Kang Liu , Jun Zhao

Large language models (LLMs) have demonstrated impressive generative capabilities with the potential to innovate in medicine. However, the application of LLMs in real clinical settings remains challenging due to the lack of factual…

The data available in Electronic Health Records (EHRs) provides the opportunity to transform care, and the best way to provide better care for one patient is through learning from the data available on all other patients. Temporal modelling…

计算与语言 · 计算机科学 2021-07-08 Zeljko Kraljevic , Anthony Shek , Daniel Bean , Rebecca Bendayan , James Teo , Richard Dobson

In electronic health record (EHR) mining, learning high-quality representations of medical concepts (e.g., standardized diagnosis, medication, and procedure codes) is fundamental for downstream clinical prediction. However, ro bust concept…

机器学习 · 计算机科学 2026-05-05 Mohsen Nayebi Kerdabadi , Arya Hadizadeh Moghaddam , Chen Chen , Dongjie Wang , Zijun Yao

Clinical documentation can be transformed by Electronic Health Records, yet the documentation process is still a tedious, time-consuming, and error-prone process. Clinicians are faced with multi-faceted requirements and fragmented…

人机交互 · 计算机科学 2021-09-24 Luke Murray , Divya Gopinath , Monica Agrawal , Steven Horng , David Sontag , David R. Karger

Knowledge Graph Completion (KGC) aims to infer missing information in Knowledge Graphs (KGs) to address their inherent incompleteness. Traditional structure-based KGC methods, while effective, face significant computational demands and…

计算与语言 · 计算机科学 2025-04-01 Jianfang Chen , Kai Zhang , Aoran Gan , Shiwei Tong , Shuanghong Shen , Qi Liu

The increasing reliance on Large Language Models (LLMs) for health information seeking can pose severe risks due to the potential for misinformation and the complexity of these topics. This paper introduces KNOWNET a visualization system…

人机交互 · 计算机科学 2024-09-27 Youfu Yan , Yu Hou , Yongkang Xiao , Rui Zhang , Qianwen Wang

Recent years have witnessed the significant damage caused by various types of fake news. Although considerable effort has been applied to address this issue and much progress has been made on detecting fake news, most existing approaches…

社会与信息网络 · 计算机科学 2021-08-11 Yi Han , Amila Silva , Ling Luo , Shanika Karunasekera , Christopher Leckie

In the modern era, abundant information is easily accessible from various sources, however only a few of these sources are reliable as they mostly contain unverified contents. We develop a system to validate the truthfulness of a given…

人工智能 · 计算机科学 2018-02-19 Papis Wongchaisuwat , Diego Klabjan

The incorporation of data analytics in the healthcare industry has made significant progress, driven by the demand for efficient and effective big data analytics solutions. Knowledge graphs (KGs) have proven utility in this arena and are…