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Recent research has extended methods from the fields of thermodynamics and statistical mechanics into other disciplines. Most notably, one recent work creates a unified theoretical framework to understand evolutionary biology, machine…

种群与进化 · 定量生物学 2024-05-22 Daniel Sadasivan , Cole Cantu , Cecilia Marsh , Andrew Graham

A natural phenomenon occurring in a living system is an outcome of the dynamics of the specific biological network underlying the phenomenon. The collective dynamics have both deterministic and stochastic components. The stochastic nature…

统计力学 · 物理学 2023-09-01 Indrani Bose

We investigate the $\Lambda$-Seed-Bank-Wright-Fisher process, a model describing allele frequency dynamics in populations exhibiting both skewed offspring distributions and dormancy. By performing a change of measure, we condition this…

The spread of synthetic gene drives is often discussed in the context of panmictic populations connected by gene flow and described with simple deterministic models. Under such assumptions, an entire species could be altered by releasing a…

种群与进化 · 定量生物学 2020-09-10 Sumit Dhole , Alun L Lloyd , Fred Gould

We study the nonequilibrium dynamics of a many-body bosonic system on a lattice, subject to driving and dissipation. The time-evolution is described by a master equation, which we treat within a generalized Gutzwiller mean field…

量子气体 · 物理学 2013-05-29 Andrea Tomadin , Sebastian Diehl , Peter Zoller

Density dependence is important in the ecology and evolution of microbial and cancer cells. Typically, we can only measure net growth rates, but the underlying density-dependent mechanisms that give rise to the observed dynamics can…

种群与进化 · 定量生物学 2025-06-04 Linh Huynh , Jacob G. Scott , Peter J. Thomas

Drying of biologically-relevant sessile droplets, including passive systems (like DNA and proteins), as well as active microbial systems comprising bacteria and algae, have garnered considerable attention over the last decades. Distinct…

软凝聚态物质 · 物理学 2023-11-07 Anusuya Pal , Amalesh Gope , Anupam Sengupta

The homeostasis of epithelial tissue relies on a balance between the self-renewal of stem cell populations, cellular differentiation, and loss. Although this balance needs to be tightly regulated to avoid pathologies, such as tumor growth,…

生物物理 · 物理学 2024-04-10 Johannes C. Krämer , Edouard Hannezo , Gerhard Gompper , Jens Elgeti

The anomalous dynamical evolution and the crossing of nonadiabatic energy levels are investigated for exactly solvable time-dependent quantum systems through a reverse-engineering scheme. By exploiting a typical driven model, we elucidate…

量子物理 · 物理学 2020-01-08 Hong Cao , Shao-Wu Yao , Li-Xiang Cen

We reconsider the deterministic haploid mutation-selection equation with two types. This is an ordinary differential equation that describes the type distribution (forward in time) in a population of infinite size. This paper establishes…

概率论 · 数学 2020-09-25 Ellen Baake , Fernando Cordero , Sebastian Hummel

Biological growth is often driven by mechanical cues, such as changes in external pressure or tensile loading. Moreover, it is well known that many living tissues actively maintain a preferred level of mechanical internal stress, called the…

生物物理 · 物理学 2018-04-24 Alexander Erlich , Derek E. Moulton , Alain Goriely

This article deals with invariant manifolds for infinite dimensional random dynamical systems with different time scales. Such a random system is generated by a coupled system of fast-slow stochastic evolutionary equations. Under suitable…

概率论 · 数学 2013-07-29 Hongbo Fu , Xianming Liu , Jinqiao Duan

We explain the principles of gene expression pattern stabilization in systems of interacting, diffusible morphogens, with dynamically established source regions. Using a reaction-diffusion model with step-function production term, we…

生物物理 · 物理学 2023-03-02 M. Majka , R. D. J. G. Ho , M. Zagorski

The regulation of a gene depends on the binding of transcription factors to specific sites located in the regulatory region of the gene. The generation of these binding sites and of cooperativity between them are essential building blocks…

统计力学 · 物理学 2007-05-23 Johannes Berg , Stana Willmann , Michael Lässig

In a standard bifurcation of a dynamical system, the stationary points (or more generally attractors) change qualitatively when varying a control parameter. Here we describe a novel unusual effect, when the change of a parameter, e.g. a…

种群与进化 · 定量生物学 2017-04-26 V. I. Yukalov , E. P. Yukalova , D. Sornette

We are interested in the dynamics of a population structured by a phenotypic trait. Individuals reproduce sexually, which is represented by a non-linear integral operator. This operator is combined to a multiplicative operator representing…

偏微分方程分析 · 数学 2021-04-14 Gaël Raoul

We present a statistical mechanics approach to the protein folding problem. We first review some of the basic properties of proteins, and introduce some physical models to describe their thermodynamics. These models rely on a random…

无序系统与神经网络 · 物理学 2008-02-03 T. Garel , H. Orland , E. Pitard

We study the collective behaviour of an ensemble of coupled motile elements whose interactions depend on time and are alternatively attractive or repulsive. The evolution of interactions is driven by individual internal variables with…

统计力学 · 物理学 2009-11-10 Damian H. Zanette , Alexander S. Mikhailov

In this article, the dynamics and complexity of a noise induced blood flow system have been investigated. Changes in the dynamics have been recognized by measuring the periodicity over significant parameters. Chaotic as well as non-chaotic…

适应与自组织系统 · 物理学 2020-01-08 Bo Yan , Sayan Mukherjee , Shaobo He

The co-evolution of network topology and dynamics is studied in an evolutionary Boolean network model that is a simple model of gene regulatory network. We find that a critical state emerges spontaneously resulting from interplay between…

统计力学 · 物理学 2007-05-23 Min Liu , Kevin E. Bassler
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