相关论文: Simultaneous elastic shape optimization for a doma…
We consider the problem of optimally insulating a given domain $\Omega$ of ${\mathbb{R}}^d$; this amounts to solve a nonlinear variational problem, where the optimal thickness of the insulator is obtained as the boundary trace of the…
This research considers the ranking and selection (R&S) problem of selecting the optimal subset from a finite set of alternative designs. Given the total simulation budget constraint, we aim to maximize the probability of correctly…
A topology optimization method is presented for the design of periodic microstructured materials with prescribed homogenized nonlinear constitutive properties over finite strain ranges. The mechanical model assumes linear elastic isotropic…
We propose a two-level structural optimization method for obtaining an approximate optimal shape of piecewise developable surface without specifying internal boundaries between surface patches. The condition for developability of a…
We propose a novel approach to optimize the design of heterogeneous materials, with the goal of enhancing their effective fracture toughness under mode-I loading. The method employs a Gaussian processes-based Bayesian optimization framework…
In this paper, we aim to solve the system of equations governing linear elasticity in parallel using domain decomposition. Through a non-overlapping decomposition of the domain, our approach aims to target the resulting interface problem,…
Bone remodeling involves the coordinated removal of bone by osteoclasts and addition of bone by osteoblasts, a process that is modulated by the prevailing mechanical environment. In this paper a fully coupled model of bone remodeling is…
We developed a novel reduced-order multi-scale method for solving large time-domain wavefield simulation problems. Our algorithm consists of two main stages. During the first "off-line" stage the fine-grid operator (of the graph Laplacian…
This paper provides a method for the simultaneous topology optimization of parts and their corresponding joint locations in an assembly. Therein, the joint locations are not discrete and predefined, but continuously movable. The underlying…
An optimization method for the design of multi-lattice structures satisfying local buckling constraints is proposed in this paper. First, the concept of free material optimization is introduced to find an optimal elastic tensor distribution…
A simulation strategy based in the finite element model was developed to model the corrosion and mechanical properties of biodegradable Mg scaffolds manufactured by laser power bed fusion after immersion in simulated body fluid. Corrosion…
Rational design strategies for self-assembly require a detailed understanding of both the equilibrium state and the assembly kinetics. While the former is starting to be well understood, the latter remains a major theoretical challenge,…
Unlike other tissue types, the nervous tissue extends to a wide and complex environment that provides a plurality of different biochemical and topological stimuli which in turn define the functions of that tissue. As a consequence of such…
Two-stage stochastic optimization is a framework for modeling uncertainty, where we have a probability distribution over possible realizations of the data, called scenarios, and decisions are taken in two stages: we make first-stage…
This study presents a computational optimisation framework of a hip implant through the development of a functionally graded biomimetic lattice structure, whose design was structurally optimised to limit stress shielding. The optimisation…
Pharmaceutical treatments can slow bone degradation, thus reducing the fracture risk inherent in osteoporosis. Antiresorptive treatments block the over-activation of osteoclasts vs osteoblasts, but the resulting decrease in bone remodeling…
In the pursuit of designing safer and more efficient energy-absorbing structures, engineers must tackle the challenge of improving crush performance while balancing multiple conflicting objectives, such as maximising energy absorption and…
In this paper, we present a framework for multiscale topology optimization of fluid-flow devices. The objective is to minimize dissipated power, subject to a desired contact-area. The proposed strategy is to design optimal microstructures…
Computational modelling offers a cost-effective and time-efficient alternative to experimental studies in biomedical engineering. In cardiac electro-mechanics, finite element method (FEM)-based simulations provide valuable insights into…
In this paper we study the asymptotic behavior of some optimal design problems related to nonlinear Steklov eigenvalues, under irregular (but diffeomorphic) perturbations of the domain.