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Research on probabilistic models of networks now spans a wide variety of fields, including physics, sociology, biology, statistics, and machine learning. These efforts have produced a diverse ecology of models and methods. Despite this…

机器学习 · 统计学 2014-11-18 Abigail Z. Jacobs , Aaron Clauset

Reconciling a gene tree with a species tree is an important task that reveals much about the evolution of genes, genomes, and species, as well as about the molecular function of genes. A wide array of computational tools have been devised…

种群与进化 · 定量生物学 2012-12-11 Yun Yu , Luay Nakhleh

In physics we often use very simple models to describe systems with many degrees of freedom, but it is not clear why or how this success can be transferred to the more complex biological context. We consider models for the joint…

神经元与认知 · 定量生物学 2024-12-06 Luisa Ramirez , William Bialek , Stephanie E. Palmer , David J. Schwab

The development of high-resolution imaging methods such as electron and scanning probe microscopy and atomic probe tomography have provided a wealth of information on structure and functionalities of solids. The availability of this data in…

材料科学 · 物理学 2022-11-08 Sergei V. Kalinin , Ayana Ghosh , Rama Vasudevan , Maxim Ziatdinov

Machine learning has been increasingly applied in climate modeling on system emulation acceleration, data-driven parameter inference, forecasting, and knowledge discovery, addressing challenges such as physical consistency, multi-scale…

Historical linguistics aims at inferring the most likely language phylogenetic tree starting from information concerning the evolutionary relatedness of languages. The available information are typically lists of homologous (lexical,…

物理与社会 · 物理学 2015-05-27 Simone Pompei , Vittorio Loreto , Francesca Tria

A probabilistic reconstruction of genealogies in a polyploid population (from 2x to 4x) is investigated, by considering genetic data analyzed as the probability of allele presence in a given genotype. Based on the likelihood of all possible…

种群与进化 · 定量生物学 2018-11-29 Frédéric Proïa , Fabien Panloup , Chiraz Trabelsi , Jérémy Clotault

Phylogenetic networks are a special type of graph which generalize phylogenetic trees and that are used to model non-treelike evolutionary processes such as recombination and hybridization. In this paper, we consider {\em unrooted}…

组合数学 · 数学 2025-05-21 Katharina T. Huber , Simone Linz , Vincent Moulton

In this review, we discuss the applications of the theory of birth-and-death processes to problems in biology, primarily, those of evolutionary genomics. The mathematical principles of the theory of these processes are briefly described.…

定量方法 · 定量生物学 2007-05-23 Artem S. Novozhilov , Georgy P. Karev , Eugene V. Koonin

The parameters of many classes of birth-death processes cannot be inferred uniquely from phylogenetic trees: infinitely many parameter combinations yield the same distribution of phylogenetic trees. Here, we show that parameter…

种群与进化 · 定量生物学 2026-04-21 Tobias Dieselhorst , Tanja Stadler

Rooted phylogenetic networks are used to describe evolutionary histories that contain non-treelike evolutionary events such as hybridization and horizontal gene transfer. In some cases, such histories can be described by a phylogenetic…

种群与进化 · 定量生物学 2016-10-03 Laura Jetten , Leo van Iersel

Phylogenetic trees (i.e. evolutionary trees, additive trees or X-trees) play a key role in the processes of modeling and representing species evolution. Genome evolution of a given group of species is usually modeled by a species…

种群与进化 · 定量生物学 2023-01-03 Vladimir Makarenkov , Gayane S. Barseghyan , Nadia Tahiri

Recent advances in statistical inference have significantly expanded the toolbox of probabilistic modeling. Historically, probabilistic modeling has been constrained to (i) very restricted model classes where exact or approximate…

机器学习 · 计算机科学 2019-10-03 Andrés R. Masegosa , Rafael Cabañas , Helge Langseth , Thomas D. Nielsen , Antonio Salmerón

Treating neural network inputs and outputs as random variables, we characterize the structure of neural networks that can be used to model data that are invariant or equivariant under the action of a compact group. Much recent research has…

机器学习 · 统计学 2020-09-18 Benjamin Bloem-Reddy , Yee Whye Teh

Phylogenetic diversity is a measure for describing how much of an evolutionary tree is spanned by a subset of species. If one applies this to the (unknown) subset of current species that will still be present at some future time, then this…

亚细胞过程 · 定量生物学 2009-09-29 Beata Faller , Fabio Pardi , Mike Steel

Reconstructing evolutionary trees from molecular sequence data is a fundamental problem in computational biology. Stochastic models of sequence evolution are closely related to spin systems that have been extensively studied in statistical…

概率论 · 数学 2017-07-20 Sebastien Roch , Allan Sly

Phylogeny is the field of modelling the temporal discrete dynamics of speciation. Complex models can nowadays be studied using the Approximate Bayesian Computation approach which avoids likelihood calculations. The field's progression is…

种群与进化 · 定量生物学 2020-11-23 Krzysztof Bartoszek , Pietro Liò

In the last years, algebraic tools have been proven useful in phylogenetic reconstruction and model selection through the study of phylogenetic invariants. However, up to now, the models studied from an algebraic viewpoint are either too…

种群与进化 · 定量生物学 2024-04-16 Marta Casanellas , Roser Homs Pons , Angélica Torres

Generative models have fundamentally reshaped the landscape of decision-making, reframing the problem from pure scalar reward maximization to high-fidelity trajectory generation and distribution matching. This paradigm shift addresses…

Bayesian inference methods rely on numerical algorithms for both model selection and parameter inference. In general, these algorithms require a high computational effort to yield reliable estimates. One of the major challenges in…

定量方法 · 定量生物学 2018-08-09 Patricio Maturana , Brendon J. Brewer , Steffen Klaere , Remco Bouckaert
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