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The interaction between actin filaments and microtubules is crucial for many eukaryotic cellular processes, such as, among others, cell polarization, cell motility and cellular wound healing. The importance of this interaction has long been…

亚细胞过程 · 定量生物学 2020-09-28 Marco Saltini , Bela M. Mulder

Reaction-diffusion equations describe various spatially extended processes that unfold as traveling fronts moving at constant velocity. We introduce and solve analytically a model that, besides such fronts, supports solutions advancing as…

生物物理 · 物理学 2026-02-13 Louis Brezin , Kyle J. Shaffer , Kirill S. Korolev

The actin cytoskeleton in living cells generates forces in conjunction with myosin motor proteins to directly and indirectly drive essential cellular processes. The semiflexible filaments of the cytoskeleton can respond nonlinearly to the…

软凝聚态物质 · 物理学 2019-12-19 D. Mizuno , C. Tardin , C. F. Schmidt

Microtubules, major elements of the cell skeleton are, most of the time, well organized in vivo, but they can also show self-organizing behaviors in time and/or space in purified solutions in vitro. Theoretical studies and models based on…

生物物理 · 物理学 2012-09-03 Nicolas Glade

We consider processes that coincide with a given diffusion process except on the boundaries of a finite collection of domains. The behavior on each of the boundaries is asymmetric: the process is much more likely to enter the interior of…

概率论 · 数学 2020-03-18 Mark Freidlin , Leonid Koralov

We study a discrete-time interacting particle system with continuous state space which is motivated by a mathematical model for turnover through branching in actin filament networks. It gives rise to transient clusters reminiscent of actin…

概率论 · 数学 2024-10-01 Cecilia González-Tokman , Dietmar B. Oelz

Active fluids have applications in micromixing, but little is known about the mixing kinematics of systems with spatiotemporally-varying activity. To investigate, UV-activated caged ATP was used to activate controlled regions of…

软凝聚态物质 · 物理学 2022-11-07 Teagan E Bate , Megan E Varney , Ezra H Taylor , Joshua H Dickie , Chih-Che Chueh , Michael M Norton , Kun-Ta Wu

The self-diffusion process in a dense liquid is influenced by collective particle movements. Extensive molecular dynamics simulations for liquid aluminium and rubidium evidence a crossover in the diffusion coefficient at about $1.4$ times…

无序系统与神经网络 · 物理学 2024-12-03 Franz Demmel , Noel Jakse

A broad range of membrane proteins display anomalous diffusion on the cell surface. Different methods provide evidence for obstructed subdiffusion and diffusion on a fractal space, but the underlying structure inducing anomalous diffusion…

生物物理 · 物理学 2017-03-15 Sanaz Sadegh , Jenny L. Higgins , Patrick C. Mannion , Michael M. Tamkun , Diego Krapf

The source term in a reaction-diffusion system, in general, does not involve explicit time dependence. A class of self-limiting growth models dealing with animal and tumor growth and bacterial population in a culture, on the other hand are…

生物物理 · 物理学 2009-11-07 Sandip Kar , Suman Kumar Banik , Deb Shankar Ray

Motivated by recent experiments showing the buckling of microtubules in cells, we study theoretically the mechanical response of, and force propagation along elastic filaments embedded in a non-linear elastic medium. We find that, although…

软凝聚态物质 · 物理学 2009-11-13 Moumita Das , Alex J. Levine , F. C. MacKintosh

Many mathematical models for biological phenomena, such as the spread of diseases, are based on reaction-diffusion equations for densities of interacting cell populations. We present a consistent derivation of reaction-diffusion equations…

偏微分方程分析 · 数学 2026-02-23 Marzia Bisi , Davide Cusseddu , Ana Jacinta Soares , Romina Travaglini

Cell shape changes are largely controlled by the actin cytoskeleton, a dynamic filament network beneath the plasma membrane. Several cell types can form extended free-standing protrusions not supported by an extracellular substrate or…

软凝聚态物质 · 物理学 2025-10-21 Kristiana Mihali , Dennis Wörthmüller , Pierre Sens

In cell membranes, proteins and lipids diffuse in a highly crowded and heterogeneous landscape, where aggregates and dense domains of proteins or lipids obstruct the path of diffusing molecules. In general, hindered motion gives rise to…

软凝聚态物质 · 物理学 2010-06-16 Margaret R. Horton , Felix Höfling , Joachim O. Rädler , Thomas Franosch

The actin cytoskeleton is a key component in the machinery of eukaryotic cells, and it selfassembles out of equilibrium into a wide variety of biologically crucial structures. While the molecular mechanisms involved are well characterized,…

软凝聚态物质 · 物理学 2017-01-04 Giulia Foffano , Nicolas Levernier , Martin Lenz

Evolution of a system of diffusing and proliferating mortal reactants is analyzed in the presence of randomly moving catalysts. While the continuum description of the problem predicts reactant extinction as the average growth rate becomes…

软凝聚态物质 · 物理学 2009-10-31 N. M. Shnerb , E. Bettelheim , Y. Louzoun , O. Agam , S. Solomon

With exquisite precision and reproducibility, cells orchestrate the cooperative action of thousands of nanometer-sized molecular motors to carry out mechanical tasks at much larger length scales, such as cell motility, division and…

软凝聚态物质 · 物理学 2013-01-08 Tim Sanchez , Daniel T. N. Chen , Stephen J. DeCamp , Michael Heymann , Zvonimir Dogic

A packed community of exponentially proliferating microbes will spread in size exponentially. However, due to nutrient depletion, mechanical constraints, or other limitations, exponential proliferation is not indefinite, and the spreading…

生物物理 · 物理学 2026-02-02 Meiyi Yao , Joshua M. Jones , Joseph W. Larkin , Andrew Mugler

We discuss the diffusion phenomenon in the parabolic and hyperbolic regimes. New effects related to the finite velocity of the diffusion process are predicted, that can partially explain the strange behavior associated to adsorption…

数学物理 · 物理学 2014-02-13 A. Sapora , M. Codegone , G. Barbero

Many cells exhibit large-scale active circulation of their entire fluid contents, a process termed cytoplasmic streaming. This phenomenon is particularly prevalent in plant cells, often presenting strikingly regimented flow patterns. The…

软凝聚态物质 · 物理学 2013-08-30 Francis G. Woodhouse , Raymond E. Goldstein
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