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Which factors govern the evolution of mutation rates and emergence of species? Here, we address this question using a first principles model of life where population dynamics of asexual organisms is coupled to molecular properties and…

种群与进化 · 定量生物学 2009-11-13 Muyoung Heo , Louis Kang , Eugene I. Shakhnovich

Consider a branching process with a homogeneous reproduction law. Sampling a single cell uniformly from the population at a time $T > 0$ and looking along the sampled cell's ancestral lineage, we find that the reproduction law is…

种群与进化 · 定量生物学 2022-05-30 David Cheek , Samuel G. G. Johnston

Signal transduction networks can form highly interconnected systems within cells due to network crosstalk, the sharing of input signals between multiple downstream responses. To better understand the evolutionary design principles…

生物物理 · 物理学 2018-02-14 Ammar Tareen , Ned S. Wingreen , Ranjan Mukhopadhyay

We study the role of recombination, as practiced by genetically-competent bacteria, in speeding up Darwinian evolution. This is done by adding a new process to a previously-studied Markov model of evolution on a smooth fitness landscape;…

种群与进化 · 定量生物学 2009-11-10 Elisheva Cohen , David A. Kessler , Herbert Levine

Starting with Darwin, biologists have asked how populations evolve from a low fitness state that is evolutionarily stable to a high fitness state that is not. Specifically of interest is the emergence of cooperation and multicellularity…

种群与进化 · 定量生物学 2015-11-10 Dervis Can Vural , Alexander Isakov , L. Mahadevan

Evolution is a fundamental process that shapes the biological world we inhabit, and reinforcement learning is a powerful tool used in artificial intelligence to develop intelligent agents that learn from their environment. In recent years,…

神经与进化计算 · 计算机科学 2023-06-19 Taboubi Ahmed

For asexual organisms point mutations correspond to local displacements in the genotypic space, while other genotypic rearrangements represent long-range jumps. We investigate the spreading properties of an initially homogeneous population…

统计力学 · 物理学 2007-05-23 Franco Bagnoli , Michele Bezzi

A major aim of evolutionary biology is to explain the respective roles of adaptive versus non-adaptive changes in the evolution of complexity. While selection is certainly responsible for the spread and maintenance of complex phenotypes,…

种群与进化 · 定量生物学 2017-01-17 Thomas LaBar , Christoph Adami

The theory of evolution by natural selection cannot be used to evaluate the truth value of the following proposition: Through evolution, there exists at least one species that can adapt to any one given environment. To address this issue,…

生物物理 · 物理学 2022-08-17 Kai Xu

We study a stochastic model proposed recently in the genetic literature to explain the heterogeneity of cell populations or of gene products. Cells are located in two colonies, whose sizes fluctuate as birth and migration processes in…

种群与进化 · 定量生物学 2007-05-23 Martin Gander , Christian Mazza , Hansklaus Rummler

The evolution in coding DNA sequences brings new flexibility and freedom to the codon words, even as the underlying nucleotides get significantly ordered. These curious contra-rules of gene organisation are observed from the distribution of…

生物物理 · 物理学 2007-05-23 Sujay Chattopadhyay , William A. Kanner , Jayprokas Chakrabarti

Biological organisms adapt to changes by processing informations from different sources, most notably from their ancestors and from their environment. We review an approach to quantify these informations by analyzing mathematical models of…

种群与进化 · 定量生物学 2016-03-23 Olivier Rivoire

Evolution of genetic code is studied as the change in the choice of enzymes that are used to synthesize amino acids from the genetic information of nucleic acids. We propose the following theory: the differentiation of physiological states…

适应与自组织系统 · 物理学 2007-05-23 H. Takagi , K. Kaneko , T. Yomo

Phenotypic variation is a hallmark of cellular physiology. Metabolic heterogeneity, in particular, underpins single-cell phenomena such as microbial drug tolerance and growth variability. Much research has focussed on transcriptomic and…

分子网络 · 定量生物学 2019-01-31 Mona K. Tonn , Philipp Thomas , Mauricio Barahona , Diego A Oyarzún

The scheme of a unified Darwinian evolutionary theory for physical and biological systems is described. Every physical system is methodologically endowed with a classical information processor what turns every system into an agent being…

综合物理 · 物理学 2019-11-26 Carlos Baladron , Andrei Khrennikov

How fast does a population evolve from one fitness peak to another? We study the dynamics of evolving, asexually reproducing populations in which a certain number of mutations jointly confer a fitness advantage. We consider the time until a…

种群与进化 · 定量生物学 2010-03-31 Chaitanya S. Gokhale , Yoh Iwasa , Martin A. Nowak , Arne Traulsen

We construct a descriptive toy model that considers quantum effects on biological evolution starting from Chaitin's classical framework. There are smart evolution scenarios in which a quantum world is as favorable as classical worlds for…

量子物理 · 物理学 2012-03-26 M. A. Martin-Delgado

Since steep declines in a population's size also typically alter its composition, population bottlenecks are considered highly important for evolution. However, despite such significance, the mechanisms governing the impact of a given…

种群与进化 · 定量生物学 2022-06-28 Emanuele Crosato , Jeffrey N. Philippson , Shashi Thutupalli , Richard G. Morris

Given a large population of players, each player has three possible choices between option 1 or 2 or no option. The two options are equally favorable and the population has to reach consensus on one of the two options quickly and in a…

系统与控制 · 计算机科学 2017-06-06 Leonardo Stella , Dario Bauso

We consider an evolution algebra which corresponds to a bisexual population with a set of females partitioned into finitely many different types and the males having only one type. We study basic properties of the algebra. This algebra is…

交换代数 · 数学 2013-07-19 M. Ladra , U. A. Rozikov
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