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We study overdamped stochastic dynamics confined by hard reflecting boundaries and show that the combination of boundary geometry and an anisotropic diffusion tensor generically generates directed motion. At the level of individual…

统计力学 · 物理学 2026-01-14 Meitar Goldfarb , Stanislav Burov

Computational modeling and simulation of fluid-structure interactions constitute a fundamental cornerstone for advancing aerospace engineering endeavors. This paper addresses the notion and implementation of the immersed boundary method for…

计算物理 · 物理学 2025-12-24 Longqing Ge , Qingdong Cai , Yonghao Zhang , Tianbai Xiao

Neural systems face the challenge of maintaining reliable representations amid variations from plasticity and spontaneous activity. In particular, the spontaneous dynamics in neuronal circuit is known to operate near a highly variable…

神经元与认知 · 定量生物学 2026-03-24 Zhuda Yang , Junhao Liang , Wing Ho Yung , Changsong Zhou

Interactions between neighboring cells are essential for generating or refining patterns in a number of biological systems. We propose a discrete filtering approach to predict how networks of cells modulate spatially varying input signals…

组织与器官 · 定量生物学 2019-02-14 Melinda Liu Perkins , Murat Arcak

A fundamental aspect of learning in biological neural networks is the plasticity property which allows them to modify their configurations during their lifetime. Hebbian learning is a biologically plausible mechanism for modeling the…

神经与进化计算 · 计算机科学 2021-03-16 Anil Yaman , Giovanni Iacca , Decebal Constantin Mocanu , Matt Coler , George Fletcher , Mykola Pechenizkiy

It has been proposed that adaptation in complex systems is optimized at the critical boundary between ordered and disordered dynamical regimes. Here, we review models of evolving dynamical networks that lead to self-organization of network…

适应与自组织系统 · 物理学 2008-11-07 Thimo Rohlf , Stefan Bornholdt

This paper proposes a solution to the problem of smooth path planning for mobile robots in dynamic and unknown environments. A novel concept of Time-Warped Grid is introduced to predict the pose of obstacles in the environment and avoid…

机器人学 · 计算机科学 2019-03-19 Siavash Farzan , Guilherme N. DeSouza

Cell migration in confining physiological environments relies on the concerted dynamics of several cellular components, including protrusions, adhesions with the environment, and the cell nucleus. However, it remains poorly understood how…

The proposed stochastic model for pedestrian dynamics is based on existing approaches using cellular automata, combined with substantial extensions, to compensate the deficiencies resulting of the discrete grid structure. This agent motion…

物理与社会 · 物理学 2021-04-01 Michael Schultz

Dynamical criticality has been shown to enhance information processing in dynamical systems, and there is evidence for self-organized criticality in neural networks. A plausible mechanism for such self-organization is activity dependent…

适应与自组织系统 · 物理学 2012-09-18 Felix Droste , Anne-Ly Do , Thilo Gross

The state space of a conventional Hopfield network typically exhibits many different attractors of which only a small subset satisfy constraints between neurons in a globally optimal fashion. It has recently been demonstrated that combining…

适应与自组织系统 · 物理学 2014-09-02 Alexander Woodward , Tom Froese , Takashi Ikegami

Representing and reasoning about physical space is fundamental to animal survival, and the mammalian lineage expresses a wealth of specialized neural representations that encode space. Grid cells, whose discovery earned a Nobel prize, are a…

神经元与认知 · 定量生物学 2023-11-29 Rylan Schaeffer , Mikail Khona , Adrian Bertagnoli , Sanmi Koyejo , Ila Rani Fiete

Humans and other organisms make decisions choosing between different options, with the aim to maximize the reward and minimize the cost. The main theoretical framework for modeling the decision-making process has been based on the highly…

神经元与认知 · 定量生物学 2024-11-19 Olga Tapinova , Tal Finkelman , Tamar Reitich-Stolero , Rony Paz , Assaf Tal , Nir S. Gov

When the motion of a motile cell is observed closely, it appears erratic, and yet the combination of nonequilibrium forces and surfaces can produce striking examples of organization in microbial systems. While most of our current…

In the absence of environmental cues, a migrating cell performs an isotropic random motion. Recently, the breaking of this isotropy has been observed when cells move in the presence of asymmetric adhesive patterns. However, up to now the…

软凝聚态物质 · 物理学 2015-06-17 M. Le Berre , Yan-Jun Liu , J. Hu , P. Maiuri , O. Bénichou , R. Voituriez , Y. Chen , M. Piel

Flexible cognition requires the ability to rapidly detect systematic functions of variables and guide future behavior based on predictions. The model described here proposes a potential framework for patterns of neural activity to detect…

神经元与认知 · 定量生物学 2018-10-17 Michael E. Hasselmo

A sufficiently large information flux in recurrent neural networks, quantified by the mutual information between successive network states, is considered a prerequisite for rich information processing capabilities. This raises the question…

神经元与认知 · 定量生物学 2026-05-15 Claus Metzner , Ali Ghebleh , Karin Prebeck , Achim Schilling , Andreas Maier , Thomas Kinfe , Patrick Krauss

Like ants, some microorganisms are known to leave trails on surfaces to communicate. We explore how trail-mediated self-interaction could affect the behavior of individual microorganisms when diffusive spreading of the trail is negligible…

生物物理 · 物理学 2016-07-15 W. Till Kranz , Anatolij Gelimson , Kun Zhao , Gerard C. L. Wong , Ramin Golestanian

Synaptic plasticity is widely accepted to be the mechanism behind learning in the brain's neural networks. A central question is how synapses, with access to only local information about the network, can still organize collectively and…

神经与进化计算 · 计算机科学 2019-12-06 Dina Obeid , Hugo Ramambason , Cengiz Pehlevan

We develop methods for investigating protein drift-diffusion dynamics in heterogeneous cell membranes and the roles played by geometry, diffusion, chemical kinetics, and phase separation. Our hybrid stochastic numerical methods combine…

生物物理 · 物理学 2023-02-28 Patrick D. Tran , Thomas A. Blanpied , Paul J. Atzberger