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We study an extreme active matter system, which is essentially a dense assembly of athermal, soft and infinitely persistent active particles. Using extensive numerical simulations we obtain jammed configurations of this system in two…

软凝聚态物质 · 物理学 2026-02-25 M. C. Gandikota , Rituparno Mandal , Pinaki Chaudhuri , Bulbul Chakraborty , Chandan Dasgupta

Motivated by rolling adhesion of white blood cells in the vasculature, we study how cells move in linear shear flow above a wall to which they can adhere via specific receptor-ligand bonds. Our computer simulations are based on a Langevin…

细胞行为 · 定量生物学 2008-04-30 C. B. Korn , U. S. Schwarz

We theoretically explore fluidization of epithelial tissues by active T1 neighbor exchanges. We show that the geometry of cell-cell junctions encodes important information about the local features of the energy landscape, which we support…

软凝聚态物质 · 物理学 2018-08-31 Matej Krajnc , Sabyasachi Dasgupta , Primož Ziherl , Jacques Prost

Experimental evidence shows that there is a feedback between cell shape and cell motion. How this feedback impacts the collective behavior of dense cell monolayers remains an open question. We investigate the effect of a feedback that tends…

The morphogenesis of cells and tissues involves an interplay between chemical signals and active forces on their surrounding surface layers. The complex interaction of hydrodynamics and material flows on such active surfaces leads to…

细胞行为 · 定量生物学 2023-06-30 Sebastian Aland , Claudia Wohlgemuth

Biological cells can exchange messages through soluble molecules or membrane-bound receptors. In particular in the latter case, the interaction is usually located in specific regions of the interacting cells and may depend on or induce…

定量方法 · 定量生物学 2023-12-12 Thorsten Prüstel , Martin Meier-Schellersheim

We establish a quantitative rigidity estimate for two-well frame-indifferent nonlinear energies, in the case in which the two wells have exactly one rank-one connection. Building upon this novel rigidity result, we then analyze solid-solid…

偏微分方程分析 · 数学 2019-12-24 Elisa Davoli , Manuel Friedrich

We present a single, unified, multi-scale model to study the attachment\detachment dynamics of two deforming, near spherical cells, coated with binding ligands and subject to a slow, homogeneous shear flow in a viscous fluid medium. The…

细胞行为 · 定量生物学 2015-04-23 Sarthok Sircar , Anthony J. Roberts

We present a large-scale molecular dynamics study of nematic-paranematic interfaces under shear. We use a model of soft repulsive ellipsoidal particles with well-known equilibrium properties, and consider interfaces which are oriented…

软凝聚态物质 · 物理学 2013-03-19 Guido Germano , Friederike Schmid

The jamming transition of frictionless athermal particles is a paradigm to understand the mechanics of amorphous materials at the atomic scale. Concepts related to the jamming transition and the mechanical response of jammed packings have…

软凝聚态物质 · 物理学 2025-02-07 Alessio Zaccone

The dynamics of sharp interfaces separating two non-hydrostatically stressed solids is analyzed using the idea that the rate of mass transport across the interface is proportional to the thermodynamic potential difference across the…

材料科学 · 物理学 2009-11-13 Luiza Angheluta , Espen Jettestuen , Joachim Mathiesen

The Vertex Model for epithelia models the apical surface of the tissue by a tiling, with polygons representing cells and edges representing cell-cell junctions. The mechanics are described by an energy governed by deviations from a target…

生物物理 · 物理学 2024-10-10 Michael F. Staddon , Carl D. Modes

We study numerically the critical behavior and marginal stability of the shear jamming transition for frictionless soft spheres, observed to occur over a finite range of densities, associated with isotropic jamming for densities above the…

软凝聚态物质 · 物理学 2022-04-27 Varghese Babu , Srikanth Sastry

Athermal packings of soft repulsive spheres exhibit a sharp jamming transition in the thermodynamic limit. Upon further compression, various structural and mechanical properties display clean power-law behavior over many decades in…

We consider a slight modification of the frog model. For a given graph, each vertex has $\mathrm{Poisson}(\lambda)$ particles (or frogs). At time zero, only the particles at the origin are active, and all the other particles are sleeping.…

概率论 · 数学 2026-01-27 Omer Angel , Daniel de la Riva , Jonathan Hermon , Yuliang Shi

Biomolecular condensates help organize the cell cytoplasm and nucleoplasm into spatial compartments with different chemical compositions. A key feature of such compositional patterning is the local enrichment of enzymatically active…

生物物理 · 物理学 2024-08-06 Andriy Goychuk , Leonardo Demarchi , Ivan Maryshev , Erwin Frey

The flow near a moving contact line depends on the dynamic contact angle, viscosity ratio, and capillary number. We report experiments involving immersing a plate into a liquid bath, concurrently measuring the interface shape, interfacial…

流体动力学 · 物理学 2024-12-04 Charul Gupta , Anjishnu Choudhury , Lakshmana D Chandrala , Harish N Dixit

Geometrical properties of two-dimensional mixtures near the jamming transition point are numerically investigated using harmonic particles under mechanical training. The configurations generated by the quasi-static compression and…

We discuss the sharp interface limit of a diffuse interface model for a two-phase flow of two partly miscible viscous Newtonian fluids of different densities, when a certain parameter \epsilon>0 related to the interface thickness tends to…

偏微分方程分析 · 数学 2012-12-24 Helmut Abels , Daniel Lengeler

We consider sharp interface asymptotics for a phase field model of two phase near spherical biomembranes involving a coupling between the local mean curvature and the local composition proposed by the first and second authors. The model is…

偏微分方程分析 · 数学 2020-12-24 Charles M. Elliott , Luke Hatcher , Björn Stinner