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Mammalian spatial navigation relies on specialized neurons, such as place and grid cells, which encode position based on self-motion and environmental cues. While extensive research has explored the computational role of grid cells, the…

神经元与认知 · 定量生物学 2026-03-02 Jared Deighton , Wyatt Mackey , Ioannis Schizas , David L. Boothe , Vasileios Maroulas

We study a rate-model neural network composed of excitatory and inhibitory neurons in which neuronal input-output functions are power laws with a power greater than 1, as observed in primary visual cortex. This supralinear input-output…

神经元与认知 · 定量生物学 2015-03-20 Yashar Ahmadian , Daniel B. Rubin , Kenneth D. Miller

We investigate spontaneous critical dynamics of excitatory and inhibitory (EI) sparsely connected populations of spiking leaky integrate-and-fire neurons with conductance-based synapses. We use a bottom-up approach to derive a single neuron…

生物物理 · 物理学 2022-04-05 Masud Ehsani , Jürgen Jost

In natural scenes, objects generally appear together with other objects. Yet, theoretical studies of neural population coding typically focus on the encoding of single objects in isolation. Experimental studies suggest that neural responses…

神经元与认知 · 定量生物学 2015-01-05 A. Emin Orhan , Wei Ji Ma

Neurons in many brain areas can develop pronounced depolarized state of membrane potential (up state) in addition to the normal hyperpolarized down state near the resting potential. The influence of the up state on signal encoding, however,…

神经元与认知 · 定量生物学 2015-09-30 Wei Wei , Fred Wolf , Xiao-Jing Wang

Fluctuations in the abundance of molecules in the living cell may affect its growth and well being. For regulatory molecules (e.g., signaling proteins or transcription factors), fluctuations in their expression can affect the levels of…

分子网络 · 定量生物学 2009-11-13 Erel Levine , Terence Hwa

The brain constructs population codes to represent stimuli through widely distributed patterns of activity across neurons. An important figure of merit of population codes is how much information about the original stimulus can be decoded…

神经元与认知 · 定量生物学 2020-08-04 Jimmy H. J. Kim , Ila Fiete , David J. Schwab

During development, the mammalian brain differentiates into specialized regions with distinct functional abilities. While many factors contribute to functional specialization, we explore the effect of neuronal density on the development of…

Increasing experimental evidence suggests that axonal action potential conduction velocity is a highly adaptive parameter in the adult central nervous system. Yet, the effects of this newfound plasticity on global brain dynamics is poorly…

神经元与认知 · 定量生物学 2019-03-26 Vladimir A. Ivanov , Ioannis E. Polykretis , Konstantinos P. Michmizos

Evolutionary dynamics and patterns of molecular evolution are strongly influenced by selection on linked regions of the genome, but our quantitative understanding of these effects remains incomplete. Recent work has focused on predicting…

种群与进化 · 定量生物学 2013-05-29 Benjamin H. Good , Michael M. Desai

We are interested in characterization of population synchronization of bursting neurons which exhibit both the slow bursting and the fast spiking timescales, in contrast to spiking neurons. Population synchronization may be well visualized…

神经元与认知 · 定量生物学 2014-10-07 Sang-Yoon Kim , Woochang Lim

We study the statistical physics of a surprising phenomenon arising in large networks of excitable elements in response to noise: while at low noise, solutions remain in the vicinity of the resting state and large-noise solutions show…

适应与自组织系统 · 物理学 2020-04-01 Jonathan D. Touboul , Charlotte Piette , Laurent Venance , G. Bard Ermentrout

We examine how the prior probability distribution of a sensory variable in the environment influences the optimal allocation of neurons and spikes in a population that represents that variable. We start with a conventional response model,…

神经元与认知 · 定量生物学 2012-09-25 Deep Ganguli , Eero Simoncelli

Focal seizures are episodes of pathological brain activity that appear to arise from a localised area of the brain. The onset patterns of focal seizure activity have been studied intensively, and they have largely been distinguished into…

神经元与认知 · 定量生物学 2017-05-08 Yujiang Wang , Andrew J Trevelyan , Antonio Valentin , Gonzalo Alarcon , Peter N Taylor , Marcus Kaiser

We report a study on the ultrafast coherent population oscillations (UCPO) in two level atoms induced by the frequency modulated few-cycle optical pulse train. The phenomenon of UCPO is investigated by numerically solving the optical Bloch…

光学 · 物理学 2013-05-30 Parvendra Kumar , Amarendra K. Sarma

Recent methods have been developed to map single-cell lineage statistics to population growth. Because population growth selects for exponentially rare phenotypes, these methods inherently depend on sampling large deviations from finite…

统计力学 · 物理学 2025-01-16 Trevor GrandPre , Ethan Levien , Ariel Amir

Neural systems process information across a broad range of intrinsic timescales, both within and across cortical areas. While such diversity is a hallmark of biological networks, its computational role in nonlinear information processing…

神经元与认知 · 定量生物学 2025-06-10 Tomoki Kurikawa

Background: Spike trains of multiple neurons can be analyzed following the summed population (SP) or the labeled line (LL) hypothesis. Responses to external stimuli are generated by a neuronal population as a whole or the individual neurons…

神经元与认知 · 定量生物学 2018-09-17 Eero Satuvuori , Mario Mulansky , Andreas Daffertshofer , Thomas Kreuz

The population model of Wilson-Cowan is perhaps the most popular in the history of computational neuroscience. It embraces the nonlinear mean field dynamics of excitatory and inhibitory neuronal populations provided via a temporal…

神经元与认知 · 定量生物学 2023-09-13 Maryam Saadati , Saba Sadat Khodaei , Yousef Jamali

Coherent population trapping is shown to occur in a driven symmetric double-well potential in the strong-field regime. The system parameters have been chosen to reproduce the $0^{-}\leftrightarrow 3^{+}$ transition of the inversion mode of…

量子物理 · 物理学 2010-07-01 V. Delgado , J. M. Gomez Llorente