Axonal Conduction Velocity Impacts Neuronal Network Oscillations
Abstract
Increasing experimental evidence suggests that axonal action potential conduction velocity is a highly adaptive parameter in the adult central nervous system. Yet, the effects of this newfound plasticity on global brain dynamics is poorly understood. In this work, we analyzed oscillations in biologically plausible neuronal networks with different conduction velocity distributions. Changes of 1-2 (ms) in network mean signal transmission time resulted in substantial network oscillation frequency changes ranging in 0-120 (Hz). Our results suggest that changes in axonal conduction velocity may significantly affect both the frequency and synchrony of brain rhythms, which have well established connections to learning, memory, and other cognitive processes.
Cite
@article{arxiv.1903.09671,
title = {Axonal Conduction Velocity Impacts Neuronal Network Oscillations},
author = {Vladimir A. Ivanov and Ioannis E. Polykretis and Konstantinos P. Michmizos},
journal= {arXiv preprint arXiv:1903.09671},
year = {2019}
}
Comments
4 pages, 5 figures, IEEE-EMBS International Conference on Biomedical and Health Informatics (BHI '19)