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Natural cilia are hair-like microtubule-based structures that are able to move fluid at low Reynolds number through asymmetric motion. In this paper we follow a biomimetic approach to design artificial cilia lining the inner surface of…

流体动力学 · 物理学 2009-09-30 S. N. Khaderi , M. G. H. M. Baltussen , P. D. Anderson , D. Ioan , J. M. J. den Toonder , P. R. Onck

Organisms use hair-like cilia that beat in a metachronal fashion to actively transport fluid and suspended particles. Metachronal motion emerges due to a phase difference between beating cycles of neighboring cilia and appears as traveling…

流体动力学 · 物理学 2018-06-13 Srinivas Hanasoge , Peter J. Hesketh , Alexander Alexeev

By numerical modeling we investigate fluid transport in low-Reynolds-number flow achieved with a special elastic filament or artifical cilium attached to a planar surface. The filament is made of superparamagnetic particles linked together…

软凝聚态物质 · 物理学 2008-11-25 Erik M. Gauger , Matthew Downton , Holger Stark

One of the vital functions of naturally occurring cilia is fluid transport. Biological cilia use spatially asymmetric strokes to generate a net fluid flow that can be utilized for feeding, swimming, and other functions. Biomimetic synthetic…

流体动力学 · 物理学 2018-07-19 Srinivas Hanasoge , Peter J. Hesketh , Alexander Alexeev

In this work we study the effect of metachronal waves on the flow created by magnetically-driven plate-like artificial cilia in microchannels using numerical simulations. The simulations are performed using a coupled magneto-mechanical…

流体动力学 · 物理学 2015-05-30 Syed Khaderi , Jaap den Toonder , Patrick Onck

Tiny cilia drive the flow of surrounding fluids through asymmetric jumping, which is one of the main ways for biological organisms to control fluid transport at the micro-scale. Due to its huge application prospects in medical and…

最优化与控制 · 数学 2024-01-08 Shuangshuang Yu , Zheng Ning , Ge Chen

Despite recent advances in artificial cilia technologies, the application of metachrony, which is the collective wavelike motion by cilia moving out-of-phase, has been severely hampered by difficulties in controlling densely packed…

In this work we mimic the efficient propulsion mechanism of natural cilia by magnetically actuating thin films in a cyclic but non-reciprocating manner. By simultaneously solving the elasto-dynamic, magnetostatic and fluid mechanics…

流体动力学 · 物理学 2009-11-13 S. N. Khaderi , M. G. H. M. Baltussen , P. D. Anderson , D. Ioan , J. M. J. den Toonder , P. R. Onck

Bio-inspired materials are commonly used in the development of functional devices. The fabrication of artificial cilia mimicking the biological functions has emerged as a promising strategy for fluid manipulation in miniaturized systems. In…

软凝聚态物质 · 物理学 2021-09-21 Aline Grein-Iankovski , Alain Graillot , Milad Radiom , Watson Loh , Jean-François Berret

Clockwise rotational movement of isolated single cilia in mice embryo was investigated in vivo. The movement generates leftward fluid flow in the node cavity and plays an important role in left-right determination. The leftward…

组织与器官 · 定量生物学 2013-05-22 Atsuko Takamatsu , Takuji Ishikawa , Kyosuke Shinohara , Hiroshi Hamada

We combine technical, experimental and theoretical efforts to investigate the collective dynamics of artificial microcilia in a viscous fluid. We take advantage of soft-lithography and colloidal self-assembly to devise microcapets made of…

Propelling microorganisms through fluids and moving fluids along cellular surfaces are essential biological functions accomplished by long, thin structures called motile cilia and flagella, whose regular, oscillatory beating breaks the…

Coordinated cilia are used throughout the natural world for micronscale fluid transport. They are often modelled with regular filament arrays on fixed, planar surfaces. Here, we simulate hundreds of interacting active filaments on spherical…

流体动力学 · 物理学 2021-12-01 Timothy A Westwood , Eric E Keaveny

One of the major challenges in modern robotics is controlling micromanipulation by active and adaptive materials. In the respiratory system, such actuation enables pathogen clearance by means of motile cilia. While various types of…

Motile cilia beat in an asymmetric fashion in order to propel the surrounding fluid. When many cilia are located on a surface, their beating can synchronise such that their phases form metachronal waves. Here, we computationally study a…

软凝聚态物质 · 物理学 2023-09-29 David J. Hickey , Ramin Golestanian , Andrej Vilfan

In a variety of biological processes, eukaryotic cells use cilia to transport flow. Although cilia have a remarkably conserved internal molecular structure, experimental observations report very diverse kinematics. To address this…

生物物理 · 物理学 2012-07-19 Christophe Eloy , Eric Lauga

Cells or bacteria carrying cilia on their surface show many striking features : alignment of cilia in an array, two-phase asymmetric beating for each cilium, coordination between cilia and existence of metachronal waves with a constant…

生物物理 · 物理学 2009-11-11 Boris Guirao , Jean-François Joanny

Motile cilia are a striking example of functional cellular organelle, conserved across all the eukaryotic species. Motile cilia allow swimming of cells and small organisms and transport of liquids across epithelial tissues. Whilst the…

组织与器官 · 定量生物学 2020-01-13 Pietro Cicuta

A variety of swimming microorganisms, called ciliates, exploit the bending of a large number of small and densely-packed organelles, termed cilia, in order to propel themselves in a viscous fluid. We consider a spherical envelope model for…

流体动力学 · 物理学 2011-08-30 Sebastien Michelin , Eric Lauga

We study a slender filament beating in a viscous fluid with novel curvature-dependent bending stiffness. Our numerical and experimental investigations reveal that such differential stiffness can sustain planar bending waves far along…

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