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The spatial responses of many of the cells recorded in all layers of rodent medial entorhinal cortex (mEC) show a triangular grid pattern, and once established might be based in part on path-integration mechanisms. Grid axes are tightly…

神经元与认知 · 定量生物学 2012-03-20 Bailu Si , Emilio Kropff , Alessandro Treves

The grid cells (GCs) of the medial entorhinal cortex (MEC) and place cells (PCs) of the hippocampus are key elements of the brain network for the metric representation of space. Currently, any of the existing theoretical models can explain…

神经元与认知 · 定量生物学 2015-07-01 Andrey Stepanyuk

Grid cells in the entorhinal cortex are believed to establish their regular, spatially correlated firing patterns by path integration of the animal's motion. Mechanisms for path integration, e.g. in attractor network models, predict…

神经元与认知 · 定量生物学 2018-08-07 Eli Pollock , Niral Desai , Xue-Xin Wei , Vijay Balasubramanian

Grid cells in the entorhinal cortex fire when animals that are exploring a certain region of space occupy the vertices of a triangular grid that spans the environment. Different neurons feature triangular grids that differ in their…

神经元与认知 · 定量生物学 2017-01-04 Alessandro Sanzeni , Vijay Balasubramanian , Guido Tiana , Massimo Vergassola

Grid cells in the brain respond when an animal occupies a periodic lattice of "grid fields" during spatial navigation. The grid scale varies along the dorso-ventral axis of the entorhinal cortex. We propose that the grid system minimizes…

神经元与认知 · 定量生物学 2018-05-14 Xue-Xin Wei , Jason Prentice , Vijay Balasubramanian

Grid cells in the medial entorhinal cortex (MEC) of the mammalian brain exhibit a strikingly regular hexagonal firing field over space. These cells are learned after birth and are thought to support spatial navigation but also more abstract…

神经元与认知 · 定量生物学 2024-10-07 Mufeng Tang , Helen Barron , Rafal Bogacz

About a decade ago grid cells were discovered in the medial entorhinal cortex of rat. Their peculiar firing patterns, which correlate with periodic locations in the environment, led to early hypothesis that grid cells may provide some form…

神经元与认知 · 定量生物学 2018-10-18 Jochen Kerdels , Gabriele Peters

Grid cells in the rodent entorhinal cortex display strikingly regular firing responses to the animal's position in 2-D space, and have been hypothesized to form the neural substrate for dead-reckoning. However, in previous models suggested…

神经元与认知 · 定量生物学 2009-02-20 Yoram Burak , Ila R. Fiete

Grid cells in the entorhinal cortex, together with head direction, place, speed and border cells, are major contributors to the organization of spatial representations in the brain. In this work we introduce a novel theoretical and…

神经元与认知 · 定量生物学 2019-07-25 Fabio Anselmi , Micah M. Murray , Benedetta Franceschiello

Grid cells in the medial entorhinal cortex (MEC) and place cells in the hippocampus (HC) both form spatial representations. Grid cells fire in triangular grid patterns, while place cells fire at specific locations and respond to contextual…

神经元与认知 · 定量生物学 2026-03-24 Zhaoze Wang , Genela Morris , Dori Derdikman , Pratik Chaudhari , Vijay Balasubramanian

Modular organization characterizes many complex networks occurring in nature, including the brain. In this paper we show that modular structure may be responsible for increasing the robustness of certain dynamical states of such systems. In…

无序系统与神经网络 · 物理学 2015-05-27 Neeraj Pradhan , Subinay Dasgupta , Sitabhra Sinha

Place cells in the hippocampus are active when an animal visits a certain location (referred to as a place field) within an environment. Grid cells in the medial entorhinal cortex (MEC) respond at multiple locations, with firing fields that…

神经元与认知 · 定量生物学 2018-05-17 David M. Schwartz , O. Ozan Koyluoglu

The activity of the grid cell population in the medial entorhinal cortex (MEC) of the mammalian brain forms a vector representation of the self-position of the animal. Recurrent neural networks have been proposed to explain the properties…

神经元与认知 · 定量生物学 2022-11-08 Dehong Xu , Ruiqi Gao , Wen-Hao Zhang , Xue-Xin Wei , Ying Nian Wu

In this paper we explain the strikingly regular activity of the 'grid' cells in rodent dorsal medial entorhinal cortex (dMEC) and the spatially localized activity of the hippocampal place cells in CA3 and CA1 by assuming that the…

神经元与认知 · 定量生物学 2008-04-22 Andras Lorincz , Melinda Kiszlinger , Gabor Szirtes

Grid cells in the medial entorhinal cortex and place cells in the hippocampus together support spatial navigation. The two regions are reciprocally connected, and there is a chicken-and-egg problem for how both arise and reinforce each…

神经元与认知 · 定量生物学 2026-05-21 Zhaoze Wang , Genela Morris , Dori Derdikman , Pratik Chaudhari , Vijay Balasubramanian

The hippocampus encodes space through a striking gradient of place field sizes along its dorsal-ventral axis, yet the principles generating this continuous gradient from discrete grid cell inputs remain debated. We propose a unified…

神经元与认知 · 定量生物学 2025-06-06 Shujun Zhou , Guozhang Chen

We present a systematic study of the influence of cell geometry on the orientational distribution of microtubules (MTs) nucleated from a single microtubule organizing center (MTOC). For simplicity we consider an elliptical cell geometry, a…

生物大分子 · 定量生物学 2022-11-30 Panayiotis Foteinopoulos , Bela M. Mulder

Kernel-based learning methods can dramatically increase the storage capacity of Hopfield networks, yet the dynamical mechanisms behind this enhancement remain poorly understood. We address this gap by combining a geometric characterization…

机器学习 · 计算机科学 2026-04-13 Akira Tamamori

Emergence of regular spatial patterns is a hallmark in living matter ranging from subcellular organelles to developing embryos and to ecosystems. Mechanisms for the formation of ordered spatial patterns in biology often require chemical…

生物物理 · 物理学 2024-03-15 Haoran Xu , Yilin Wu

Modeling and understanding the environment is an essential task for autonomous driving. In addition to the detection of objects, in complex traffic scenarios the motion of other road participants is of special interest. Therefore, we…

机器人学 · 计算机科学 2022-05-06 Marcel Schreiber , Vasileios Belagiannis , Claudius Gläser , Klaus Dietmayer
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